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Cytotoxic activity of copper(ii), nickel(ii) and platinum(ii) thiosemicarbazone derivatives: interaction with DNA and the H2A histone peptide.

Bisceglie F, Orsoni N, Pioli M, Bonati B, Tarasconi P, Rivetti C, Amidani D, Montalbano S, Buschini A, Pelosi G.

Metallomics. 2019 Sep 10. doi: 10.1039/c9mt00166b. [Epub ahead of print]


Sabotage at the Powerhouse? Unraveling the Molecular Target of 2-Isopropylbenzaldehyde Thiosemicarbazone, a Specific Inhibitor of Aflatoxin Biosynthesis and Sclerotia Development in Aspergillus flavus, Using Yeast as a Model System.

Dallabona C, Pioli M, Spadola G, Orsoni N, Bisceglie F, Lodi T, Pelosi G, Restivo FM, Degola F.

Molecules. 2019 Aug 16;24(16). pii: E2971. doi: 10.3390/molecules24162971.


Structural modification of cuminaldehyde thiosemicarbazone increases inhibition specificity toward aflatoxin biosynthesis and sclerotia development in Aspergillus flavus.

Degola F, Bisceglie F, Pioli M, Palmano S, Elviri L, Pelosi G, Lodi T, Restivo FM.

Appl Microbiol Biotechnol. 2017 Sep;101(17):6683-6696. doi: 10.1007/s00253-017-8426-y. Epub 2017 Jul 19.


A battery of assays as an integrated approach to evaluate fungal and mycotoxin inhibition properties and cytotoxic/genotoxic side-effects for the prioritization in the screening of thiosemicarbazone derivatives.

Zani C, Bisceglie F, Restivo FM, Feretti D, Pioli M, Degola F, Montalbano S, Galati S, Pelosi G, Viola GVC, Carcelli M, Rogolino D, Ceretti E, Buschini A.

Food Chem Toxicol. 2017 Jul;105:498-505. doi: 10.1016/j.fct.2017.05.008. Epub 2017 May 5.


Autophagy and apoptosis: studies on the effects of bisthiosemicarbazone copper(ii) complexes on p53 and p53-null tumour cell lines.

Bisceglie F, Alinovi R, Pinelli S, Galetti M, Pioli M, Tarasconi P, Mutti A, Goldoni M, Pelosi G.

Metallomics. 2016 Dec 7;8(12):1255-1265.


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