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Items: 1 to 20 of 22


The Role of IL-33/ST2 Pathway in Tumorigenesis.

Larsen KM, Minaya MK, Vaish V, Peña MMO.

Int J Mol Sci. 2018 Sep 9;19(9). pii: E2676. doi: 10.3390/ijms19092676. Review.


Elevated interleukin-27 levels in human neonatal macrophages regulate indoleamine dioxygenase in a STAT-1 and STAT-3-dependent manner.

Jung JY, Gleave Parson M, Kraft JD, Lyda L, Kobe B, Davis C, Robinson J, Peña MM, Robinson CM.

Immunology. 2016 Sep;149(1):35-47. doi: 10.1111/imm.12625.


IL-33 promotes growth and liver metastasis of colorectal cancer in mice by remodeling the tumor microenvironment and inducing angiogenesis.

Zhang Y, Davis C, Shah S, Hughes D, Ryan JC, Altomare D, Peña MM.

Mol Carcinog. 2017 Jan;56(1):272-287. doi: 10.1002/mc.22491. Epub 2016 Apr 27.


Redox potential ultrasensitive nanoparticle for the targeted delivery of camptothecin to HER2-positive cancer cells.

Remant BK, Chandrashekaran V, Cheng B, Chen H, Peña MM, Zhang J, Montgomery J, Xu P.

Mol Pharm. 2014 Jun 2;11(6):1897-905. doi: 10.1021/mp5000482. Epub 2014 May 9.


Development and characterization of a reliable mouse model of colorectal cancer metastasis to the liver.

Zhang Y, Davis C, Ryan J, Janney C, Peña MM.

Clin Exp Metastasis. 2013 Oct;30(7):903-18. doi: 10.1007/s10585-013-9591-8. Epub 2013 Jun 9.


Neonatal macrophages express elevated levels of interleukin-27 that oppose immune responses.

Kraft JD, Horzempa J, Davis C, Jung JY, Peña MM, Robinson CM.

Immunology. 2013 Aug;139(4):484-93. doi: 10.1111/imm.12095.


Hematopoietic derived cell infiltration of the intestinal tumor microenvironment in Apc Min/+ mice.

Davis C, Price R, Acharya G, Baudino T, Borg T, Berger FG, Peña MM.

Microsc Microanal. 2011 Aug;17(4):528-39. doi: 10.1017/S1431927611000043. Epub 2011 Apr 8.


Distinguishing between cancer driver and passenger gene alteration candidates via cross-species comparison: a pilot study.

Ji X, Tang J, Halberg R, Busam D, Ferriera S, Peña MM, Venkataramu C, Yeatman TJ, Zhao S.

BMC Cancer. 2010 Aug 13;10:426. doi: 10.1186/1471-2407-10-426.


Activity level, apoptosis, and development of cachexia in Apc(Min/+) mice.

Baltgalvis KA, Berger FG, Peña MM, Mark Davis J, White JP, Carson JA.

J Appl Physiol (1985). 2010 Oct;109(4):1155-61. doi: 10.1152/japplphysiol.00442.2010. Epub 2010 Jul 22.


Replacement of Val3 in human thymidylate synthase affects its kinetic properties and intracellular stability .

Huang X, Gibson LM, Bell BJ, Lovelace LL, Peña MM, Berger FG, Berger SH, Lebioda L.

Biochemistry. 2010 Mar 23;49(11):2475-82. doi: 10.1021/bi901457e.


The intrinsically disordered N-terminal domain of thymidylate synthase targets the enzyme to the ubiquitin-independent proteasomal degradation pathway.

Peña MM, Melo SP, Xing YY, White K, Barbour KW, Berger FG.

J Biol Chem. 2009 Nov 13;284(46):31597-607. doi: 10.1074/jbc.M109.038455. Epub 2009 Sep 21.


The interaction of a high-fat diet and regular moderate intensity exercise on intestinal polyp development in Apc Min/+ mice.

Baltgalvis KA, Berger FG, Peña MM, Davis JM, Carson JA.

Cancer Prev Res (Phila). 2009 Jul;2(7):641-9. doi: 10.1158/1940-6207.CAPR-09-0017. Epub 2009 Jun 23.


Beta-catenin induces beta-TrCP-mediated PER2 degradation altering circadian clock gene expression in intestinal mucosa of ApcMin/+ mice.

Yang X, Wood PA, Ansell CM, Ohmori M, Oh EY, Xiong Y, Berger FG, Peña MM, Hrushesky WJ.

J Biochem. 2009 Mar;145(3):289-97. doi: 10.1093/jb/mvn167. Epub 2008 Dec 23.


Period 2 mutation accelerates ApcMin/+ tumorigenesis.

Wood PA, Yang X, Taber A, Oh EY, Ansell C, Ayers SE, Al-Assaad Z, Carnevale K, Berger FG, Peña MM, Hrushesky WJ.

Mol Cancer Res. 2008 Nov;6(11):1786-93. doi: 10.1158/1541-7786.MCR-08-0196.


Muscle wasting and interleukin-6-induced atrogin-I expression in the cachectic Apc ( Min/+ ) mouse.

Baltgalvis KA, Berger FG, Peña MM, Davis JM, White JP, Carson JA.

Pflugers Arch. 2009 Mar;457(5):989-1001. doi: 10.1007/s00424-008-0574-6. Epub 2008 Aug 19.


Effect of exercise on biological pathways in ApcMin/+ mouse intestinal polyps.

Baltgalvis KA, Berger FG, Peña MM, Davis JM, Carson JA.

J Appl Physiol (1985). 2008 Apr;104(4):1137-43. doi: 10.1152/japplphysiol.00955.2007. Epub 2008 Jan 31.


Interleukin-6 and cachexia in ApcMin/+ mice.

Baltgalvis KA, Berger FG, Pena MM, Davis JM, Muga SJ, Carson JA.

Am J Physiol Regul Integr Comp Physiol. 2008 Feb;294(2):R393-401. Epub 2007 Dec 5.


Developmental abnormalities in multiple proliferative tissues of Apc(Min/+) mice.

You S, Ohmori M, Peña MM, Nassri B, Quiton J, Al-Assad ZA, Liu L, Wood PA, Berger SH, Liu Z, Wyatt MD, Price RL, Berger FG, Hrushesky WJ.

Int J Exp Pathol. 2006 Jun;87(3):227-36.


Role of N-terminal residues in the ubiquitin-independent degradation of human thymidylate synthase.

Peña MM, Xing YY, Koli S, Berger FG.

Biochem J. 2006 Feb 15;394(Pt 1):355-63.


Structural determinants for the intracellular degradation of human thymidylate synthase.

Forsthoefel AM, Peña MM, Xing YY, Rafique Z, Berger FG.

Biochemistry. 2004 Feb 24;43(7):1972-9.


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