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Items: 1 to 20 of 59

1.

Protective Effects of BACE1 Inhibitory Ligand Molecules Against Amyloid Beta-Induced Synaptic and Mitochondrial Toxicities in Alzheimer's Disease.

Pradeepkiran JA, Reddy AP, Yin X, Manczak M, Reddy PH.

Hum Mol Genet. 2019 Oct 9. pii: ddz227. doi: 10.1093/hmg/ddz227. [Epub ahead of print]

PMID:
31595293
2.

Current Status of Healthy Aging and Dementia Research: A Symposium Summary.

Reddy PH, Swerdlow RH, Culberson J, Kang D, Mitchell TL, Smith Q, Suneja S, Ory MG, Kumar S, Vijayan M, Morsy A, Arandia G, Lawrence JJ, George E, Oliver D, Pradeepkiran JA, Yin X, Reddy AP, Manczak M, Cengiz P, Karamyan VT, Kandimalla R, Kuruva CS, Willms J, Ramasubramanian B, Sawant N, Burugu D, Boles AN, Lopez V, Carrasco R, Aguirre C, Thompson S, Blackmon J, Ament C, Wang R, Stephens ER, Hoang B, Bass K, Trippier PC, Hornback C, Kottapalli P, Kottapalli KR; Center Biotechnology and Genetics Core Facility, Oddo S.

J Alzheimers Dis. 2019;72(s1):S11-S35. doi: 10.3233/JAD-190252.

PMID:
31104030
3.

Corrigendum: Mitochondrial division inhibitor 1 reduces dynamin-related protein 1 and mitochondrial fission activity.

Manczak M, Kandimalla R, Yin X, Hemachandra Reddy P.

Hum Mol Genet. 2019 Mar 1;28(5):875-876. doi: 10.1093/hmg/ddy399. No abstract available.

4.

Mitochondrial division inhibitor 1 reduces dynamin-related protein 1 and mitochondrial fission activity.

Manczak M, Kandimalla R, Yin X, Reddy PH.

Hum Mol Genet. 2019 Jan 15;28(2):177-199. doi: 10.1093/hmg/ddy335. Erratum in: Hum Mol Genet. 2019 Mar 1;28(5):875-876.

5.

Mutant APP and amyloid beta-induced defective autophagy, mitophagy, mitochondrial structural and functional changes and synaptic damage in hippocampal neurons from Alzheimer's disease.

Reddy PH, Yin X, Manczak M, Kumar S, Pradeepkiran JA, Vijayan M, Reddy AP.

Hum Mol Genet. 2018 Jul 15;27(14):2502-2516. doi: 10.1093/hmg/ddy154.

7.

Synergistic Protective Effects of Mitochondrial Division Inhibitor 1 and Mitochondria-Targeted Small Peptide SS31 in Alzheimer's Disease.

Reddy PH, Manczak M, Yin X, Reddy AP.

J Alzheimers Dis. 2018;62(4):1549-1565. doi: 10.3233/JAD-170988.

8.

Protective Effects of Indian Spice Curcumin Against Amyloid-β in Alzheimer's Disease.

Reddy PH, Manczak M, Yin X, Grady MC, Mitchell A, Tonk S, Kuruva CS, Bhatti JS, Kandimalla R, Vijayan M, Kumar S, Wang R, Pradeepkiran JA, Ogunmokun G, Thamarai K, Quesada K, Boles A, Reddy AP.

J Alzheimers Dis. 2018;61(3):843-866. doi: 10.3233/JAD-170512. Review.

9.

Hippocampal phosphorylated tau induced cognitive decline, dendritic spine loss and mitochondrial abnormalities in a mouse model of Alzheimer's disease.

Kandimalla R, Manczak M, Yin X, Wang R, Reddy PH.

Hum Mol Genet. 2018 Jan 1;27(1):30-40. doi: 10.1093/hmg/ddx381.

10.
11.

Mitochondria-targeted small molecule SS31: a potential candidate for the treatment of Alzheimer's disease.

Reddy PH, Manczak M, Kandimalla R.

Hum Mol Genet. 2017 Apr 15;26(8):1597. doi: 10.1093/hmg/ddx129. No abstract available.

12.
13.

Maternal exercise upregulates mitochondrial gene expression and increases enzyme activity of fetal mouse hearts.

Chung E, Joiner HE, Skelton T, Looten KD, Manczak M, Reddy PH.

Physiol Rep. 2017 Mar;5(5). pii: e13184. doi: 10.14814/phy2.13184.

14.

Mitochondria-targeted small molecule SS31: a potential candidate for the treatment of Alzheimer's disease.

Reddy PH, Manczak M, Kandimalla R.

Hum Mol Genet. 2017 Apr 15;26(8):1483-1496. doi: 10.1093/hmg/ddx052. Erratum in: Hum Mol Genet. 2017 Apr 15;26(8):1597.

15.

Reduced dynamin-related protein 1 protects against phosphorylated Tau-induced mitochondrial dysfunction and synaptic damage in Alzheimer's disease.

Kandimalla R, Manczak M, Fry D, Suneetha Y, Sesaki H, Reddy PH.

Hum Mol Genet. 2016 Nov 15;25(22):4881-4897. doi: 10.1093/hmg/ddw312.

16.

Protective effects of reduced dynamin-related protein 1 against amyloid beta-induced mitochondrial dysfunction and synaptic damage in Alzheimer's disease.

Manczak M, Kandimalla R, Fry D, Sesaki H, Reddy PH.

Hum Mol Genet. 2016 Dec 1;25(23):5148-5166. doi: 10.1093/hmg/ddw330.

17.

Protective effects of a natural product, curcumin, against amyloid β induced mitochondrial and synaptic toxicities in Alzheimer's disease.

Reddy PH, Manczak M, Yin X, Grady MC, Mitchell A, Kandimalla R, Kuruva CS.

J Investig Med. 2016 Dec;64(8):1220-1234. Epub 2016 Aug 12.

18.

Mitochondria-targeted molecules MitoQ and SS31 reduce mutant huntingtin-induced mitochondrial toxicity and synaptic damage in Huntington's disease.

Yin X, Manczak M, Reddy PH.

Hum Mol Genet. 2016 May 1;25(9):1739-53. doi: 10.1093/hmg/ddw045. Epub 2016 Feb 16.

19.
20.

Garrison Institute on Aging: A New Hope for Elderly Individuals and Patients with Alzheimer's Disease.

Reddy PH, Blackmon J, Molinar-Lopez V, Ament C, Manczak M, Kandimalla R, Yin X, Pandey A, Kuruva CS, Wang R, Fry D, Osborn C, Stonum K, Quesada K, Gonzales R, Boles A.

J Alzheimers Dis. 2015;48(2):547-55. doi: 10.3233/JAD-150490.

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