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Items: 19


Methylamine Activates Glucose Uptake in Human Adipocytes Without Overpassing Action of Insulin or Stimulating its Secretion in Pancreatic Islets.

Carpéné C, Mauriège P, Boulet N, Biron S, Grolleau JL, Garcia-Barrado MJ, Iglesias-Osma MC.

Medicines (Basel). 2019 Aug 12;6(3). pii: E89. doi: 10.3390/medicines6030089.


The influence of the lack of insulin receptor substrate 2 (IRS2) on the thyroid gland.

Iglesias-Osma MC, Blanco EJ, Carretero-Hernandez M, Catalano-Iniesta L, Sanchez-Robledo V, Garcia-Barrado MJ, Vicente-Garcia T, Burks DJ, Carretero J.

Sci Rep. 2019 Apr 5;9(1):5673. doi: 10.1038/s41598-019-42198-7.


Sequential testicular atrophy involves changes in cellular proliferation and apoptosis associated with variations in aromatase P450 expression levels in Irs-2-deficient mice.

Catalano-Iniesta L, Sánchez-Robledo V, Iglesias-Osma MC, García-Barrado MJ, Carretero-Hernández M, Blanco EJ, Vicente-García T, Burks DJ, Carretero J.

J Anat. 2019 Feb;234(2):227-243. doi: 10.1111/joa.12917. Epub 2018 Nov 25.


Variations in adrenal gland medulla and dopamine effects induced by the lack of Irs2.

Catalano-Iniesta L, Iglesias-Osma MC, Sánchez-Robledo V, Carretero-Hernández M, Blanco EJ, Carretero J, García-Barrado MJ.

J Physiol Biochem. 2018 Nov;74(4):667-677. doi: 10.1007/s13105-018-0655-8. Epub 2018 Oct 26.


Prolactin system in the hippocampus.

Carretero J, Sánchez-Robledo V, Carretero-Hernández M, Catalano-Iniesta L, García-Barrado MJ, Iglesias-Osma MC, Blanco EJ.

Cell Tissue Res. 2019 Jan;375(1):193-199. doi: 10.1007/s00441-018-2858-2. Epub 2018 May 28. Review.


Relation among Aromatase P450 and Tumoral Growth in Human Prolactinomas.

García-Barrado MJ, Blanco EJ, Iglesias-Osma MC, Carretero-Hernández M, Catalano-Iniesta L, Sanchez-Robledo V, Carretero M, Herrero JJ, Carrero S, Carretero J.

Int J Mol Sci. 2017 Nov 1;18(11). pii: E2299. doi: 10.3390/ijms18112299. Review.


Endothelial immunocytochemical expression of pituitary IL-1β and its relation to ACTH-positive cells is regulated by corticosterone in the male rat.

Iglesias-Osma MC, Blanco EJ, Carretero-Hernández M, García-Barrado MJ, Catalano-Iniesta L, Carretero M, Sánchez-Robledo V, Carretero J.

Cytokine. 2017 Nov;99:9-17. doi: 10.1016/j.cyto.2017.06.020. Epub 2017 Jul 1.


Pituitary Aromatase P450 May Be Involved in Maintenance of the Population of Luteinizing Hormone-Positive Pituitary Cells in Mice.

Carretero J, López F, Catalano-Iniesta L, Sanchez-Robledo V, Garcia-Barrado MJ, Iglesias-Osma MC, Carretero-Hernandez M, Blanco EJ, Burks DJ.

Cells Tissues Organs. 2016;201(5):390-8. doi: 10.1159/000445478. Epub 2016 May 5.


Relevance of pituitary aromatase and estradiol on the maintenance of the population of prolactin-positive cells in male mice.

García-Barrado MJ, Blanco EJ, Catalano-Iniesta L, Sanchez-Robledo V, Iglesias-Osma MC, Carretero-Hernández M, Rodríguez-Cobos J, Burks DJ, Carretero J.

Steroids. 2016 Jul;111:121-126. doi: 10.1016/j.steroids.2016.03.020. Epub 2016 Apr 1.


Dopamine modulates insulin release and is involved in the survival of rat pancreatic beta cells.

Garcia Barrado MJ, Iglesias Osma MC, Blanco EJ, Carretero Hernández M, Sánchez Robledo V, Catalano Iniesta L, Carrero S, Carretero J.

PLoS One. 2015 Apr 17;10(4):e0123197. doi: 10.1371/journal.pone.0123197. eCollection 2015.


Local transformations of androgens into estradiol by aromatase P450 is involved in the regulation of prolactin and the proliferation of pituitary prolactin-positive cells.

García Barrado MJ, Blanco EJ, Carretero Hernández M, Iglesias Osma MC, Carretero M, Herrero JJ, Burks DJ, Carretero J.

PLoS One. 2014 Jun 30;9(6):e101403. doi: 10.1371/journal.pone.0101403. eCollection 2014.


Is there an optimal dose for dietary linoleic acid? Lessons from essential fatty acid deficiency supplementation and adipocyte functions in rats.

Harant-Farrugia I, Garcia J, Iglesias-Osma MC, Garcia-Barrado MJ, Carpéné C.

J Physiol Biochem. 2014 Jun;70(2):615-27. doi: 10.1007/s13105-014-0315-6. Epub 2014 Feb 1.


Differential sensitivity to adrenergic stimulation underlies the sexual dimorphism in the development of diabetes caused by Irs-2 deficiency.

Garcia-Barrado MJ, Iglesias-Osma MC, Moreno-Viedma V, Pastor Mansilla MF, Gonzalez SS, Carretero J, Moratinos J, Burks DJ.

Biochem Pharmacol. 2011 Jan 15;81(2):279-88. doi: 10.1016/j.bcp.2010.10.008. Epub 2010 Oct 17.


Oral insulin-mimetic compounds that act independently of insulin.

García-Vicente S, Yraola F, Marti L, González-Muñoz E, García-Barrado MJ, Cantó C, Abella A, Bour S, Artuch R, Sierra C, Brandi N, Carpéné C, Moratinos J, Camps M, Palacín M, Testar X, Gumà A, Albericio F, Royo M, Mian A, Zorzano A.

Diabetes. 2007 Feb;56(2):486-93.


The imidazoline I2-site ligands BU 224 and 2-BFI inhibit MAO-A and MAO-B activities, hydrogen peroxide production, and lipolysis in rodent and human adipocytes.

Bour S, Iglesias-Osma MC, Marti L, Duro P, Garcia-Barrado MJ, Pastor MF, Prévot D, Visentin V, Valet P, Moratinos J, Carpéné C.

Eur J Pharmacol. 2006 Dec 15;552(1-3):20-30. Epub 2006 Sep 23.


Methylamine but not mafenide mimics insulin-like activity of the semicarbazide-sensitive amine oxidase-substrate benzylamine on glucose tolerance and on human adipocyte metabolism.

Iglesias-Osma MC, Bour S, Garcia-Barrado MJ, Visentin V, Pastor MF, Testar X, Marti L, Enrique-Tarancon G, Valet P, Moratinos J, Carpéné C.

Pharmacol Res. 2005 Dec;52(6):475-84. Epub 2005 Aug 30.


Benzylamine exhibits insulin-like effects on glucose disposal, glucose transport, and fat cell lipolysis in rabbits and diabetic mice.

Iglesias-Osma MC, Garcia-Barrado MJ, Visentin V, Pastor-Mansilla MF, Bour S, Prévot D, Valet P, Moratinos J, Carpéné C.

J Pharmacol Exp Ther. 2004 Jun;309(3):1020-8. Epub 2004 Feb 20.


Ras-GRF1 signaling is required for normal beta-cell development and glucose homeostasis.

Font de Mora J, Esteban LM, Burks DJ, Núñez A, Garcés C, García-Barrado MJ, Iglesias-Osma MC, Moratinos J, Ward JM, Santos E.

EMBO J. 2003 Jun 16;22(12):3039-49.


Role of mu-opioid receptors in insulin release in the presence of inhibitory and excitatory secretagogues.

García-Barrado MJ, Iglesias-Osma MC, Rodríguez R, Martín M, Moratinos J.

Eur J Pharmacol. 2002 Jul 12;448(1):95-104.


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