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Items: 11


Hosts for Hostile Protein Production: The Challenge of Recombinant Immunotoxin Expression.

Zuppone S, Fabbrini MS, Vago R.

Biomedicines. 2019 May 17;7(2). pii: E38. doi: 10.3390/biomedicines7020038. Review.


Strategies to Improve the Clinical Utility of Saporin-Based Targeted Toxins.

Giansanti F, Flavell DJ, Angelucci F, Fabbrini MS, Ippoliti R.

Toxins (Basel). 2018 Feb 13;10(2). pii: E82. doi: 10.3390/toxins10020082. Review.


Plant Ribosome-Inactivating Proteins: Progesses, Challenges and Biotechnological Applications (and a Few Digressions).

Fabbrini MS, Katayama M, Nakase I, Vago R.

Toxins (Basel). 2017 Oct 12;9(10). pii: E314. doi: 10.3390/toxins9100314. Review.


Optimization of construct design and fermentation strategy for the production of bioactive ATF-SAP, a saporin based anti-tumoral uPAR-targeted chimera.

Errico Provenzano A, Posteri R, Giansanti F, Angelucci F, Flavell SU, Flavell DJ, Fabbrini MS, Porro D, Ippoliti R, Ceriotti A, Branduardi P, Vago R.

Microb Cell Fact. 2016 Nov 14;15(1):194.


Systematic comparison of single-chain Fv antibody-fusion toxin constructs containing Pseudomonas Exotoxin A or saporin produced in different microbial expression systems.

Della Cristina P, Castagna M, Lombardi A, Barison E, Tagliabue G, Ceriotti A, Koutris I, Di Leandro L, Giansanti F, Vago R, Ippoliti R, Flavell SU, Flavell DJ, Colombatti M, Fabbrini MS.

Microb Cell Fact. 2015 Feb 13;14:19. doi: 10.1186/s12934-015-0202-z.


Ribosome-inactivating proteins: from plant defense to tumor attack.

de Virgilio M, Lombardi A, Caliandro R, Fabbrini MS.

Toxins (Basel). 2010 Nov;2(11):2699-737. doi: 10.3390/toxins2112699. Epub 2010 Nov 10. Review.


Signal peptide-regulated toxicity of a plant ribosome-inactivating protein during cell stress.

Marshall RS, D'Avila F, Di Cola A, Traini R, Spanò L, Fabbrini MS, Ceriotti A.

Plant J. 2011 Jan;65(2):218-29. doi: 10.1111/j.1365-313X.2010.04413.x. Epub 2010 Nov 29.


Engineering a switchable toxin: the potential use of PDZ domains in the expression, targeting and activation of modified saporin variants.

Giansanti F, Di Leandro L, Koutris I, Pitari G, Fabbrini MS, Lombardi A, Flavell DJ, Flavell SU, Gianni S, Ippoliti R.

Protein Eng Des Sel. 2010 Feb;23(2):61-8. doi: 10.1093/protein/gzp070. Epub 2009 Nov 23.


Pichia pastoris as a host for secretion of toxic saporin chimeras.

Lombardi A, Bursomanno S, Lopardo T, Traini R, Colombatti M, Ippoliti R, Flavell DJ, Flavell SU, Ceriotti A, Fabbrini MS.

FASEB J. 2010 Jan;24(1):253-65. doi: 10.1096/fj.08-118042. Epub 2009 Sep 28.


Saporin suicide gene therapy.

Zarovni N, Vago R, Fabbrini MS.

Methods Mol Biol. 2009;542:261-83. doi: 10.1007/978-1-59745-561-9_14.


Exogenous protein expression in Xenopus oocytes: basic procedures.

Bossi E, Fabbrini MS, Ceriotti A.

Methods Mol Biol. 2007;375:107-31. Review.


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