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Items: 3

1.

Discovery of potent nucleotide-mimicking competitive inhibitors of hepatitis C virus NS3 helicase.

Gemma S, Butini S, Campiani G, Brindisi M, Zanoli S, Romano MP, Tripaldi P, Savini L, Fiorini I, Borrelli G, Novellino E, Maga G.

Bioorg Med Chem Lett. 2011 May 1;21(9):2776-9. doi: 10.1016/j.bmcl.2010.09.002. Epub 2010 Sep 6.

PMID:
20880703
2.

Design, synthesis, and structure-activity relationship studies of 4-quinolinyl- and 9-acrydinylhydrazones as potent antimalarial agents.

Fattorusso C, Campiani G, Kukreja G, Persico M, Butini S, Romano MP, Altarelli M, Ros S, Brindisi M, Savini L, Novellino E, Nacci V, Fattorusso E, Parapini S, Basilico N, Taramelli D, Yardley V, Croft S, Borriello M, Gemma S.

J Med Chem. 2008 Mar 13;51(5):1333-43. doi: 10.1021/jm7012375. Epub 2008 Feb 16.

PMID:
18278859
3.

Specific targeting of hepatitis C virus NS3 RNA helicase. Discovery of the potent and selective competitive nucleotide-mimicking inhibitor QU663.

Maga G, Gemma S, Fattorusso C, Locatelli GA, Butini S, Persico M, Kukreja G, Romano MP, Chiasserini L, Savini L, Novellino E, Nacci V, Spadari S, Campiani G.

Biochemistry. 2005 Jul 19;44(28):9637-44.

PMID:
16008349

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