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Items: 1 to 20 of 80

1.
2.

Possible Biosynthetic Products and Metabolites of Kainic Acid from the Red Alga Digenea simplex and Their Biological Activity.

Maeno Y, Terada R, Kotaki Y, Cho Y, Konoki K, Yotsu-Yamashita M.

J Nat Prod. 2019 May 22. doi: 10.1021/acs.jnatprod.9b00128. [Epub ahead of print]

PMID:
31117523
3.

Metabolomic study of saxitoxin analogues and biosynthetic intermediates in dinoflagellates using 15N-labelled sodium nitrate as a nitrogen source.

Cho Y, Tsuchiya S, Omura T, Koike K, Oikawa H, Konoki K, Oshima Y, Yotsu-Yamashita M.

Sci Rep. 2019 Mar 5;9(1):3460. doi: 10.1038/s41598-019-39708-y.

4.

Total Syntheses and Determination of Absolute Configurations of Cep-212 and Cep-210, Predicted Biosynthetic Intermediates of Tetrodotoxin Isolated from Toxic Newt.

Adachi M, Miyasaka T, Kudo Y, Sugimoto K, Yotsu-Yamashita M, Nishikawa T.

Org Lett. 2019 Feb 1;21(3):780-784. doi: 10.1021/acs.orglett.8b04043. Epub 2019 Jan 10.

PMID:
30628790
5.

Lack of alkaloids and tetrodotoxin in the neotropical frogs Allobates spp. (Aromobatidae) and Silverstoneia flotator (Dendrobatidae).

Mebs D, Yotsu-Yamashita M, Pogoda W, Vargas Alvarez J, Ernst R, Köhler G, Toennes SW.

Toxicon. 2018 Sep 15;152:103-105. doi: 10.1016/j.toxicon.2018.07.027. Epub 2018 Aug 4.

PMID:
30081062
6.

A Novel Compound, "FA-1" Isolated from Prunus mume, Protects Human Bronchial Epithelial Cells and Keratinocytes from Cigarette Smoke Extract-Induced Damage.

Jang AJ, Lee JH, Yotsu-Yamashita M, Park J, Kye S, Benza RL, Passineau MJ, Jeon YJ, Nyunoya T.

Sci Rep. 2018 Jul 31;8(1):11504. doi: 10.1038/s41598-018-29701-2.

7.
8.

Geographic range expansion of tetrodotoxin in amphibians - First record in Atelopus hoogmoedi from the Guiana Shield.

Mebs D, Lorentz M, Yotsu-Yamashita M, Rößler DC, Ernst R, Lötters S.

Toxicon. 2018 Aug;150:175-179. doi: 10.1016/j.toxicon.2018.05.011. Epub 2018 May 19.

PMID:
29782950
9.

Spiro Bicyclic Guanidino Compounds from Pufferfish: Possible Biosynthetic Intermediates of Tetrodotoxin in Marine Environments.

Ueyama N, Sugimoto K, Kudo Y, Onodera KI, Cho Y, Konoki K, Nishikawa T, Yotsu-Yamashita M.

Chemistry. 2018 May 17;24(28):7250-7258. doi: 10.1002/chem.201801006. Epub 2018 Apr 30.

PMID:
29504641
10.

Effects of 4,9-anhydrotetrodotoxin on voltage-gated Na+ channels of mouse vas deferens myocytes and recombinant NaV1.6 channels.

Takahara K, Yamamoto T, Uchida K, Zhu HL, Shibata A, Inai T, Noguchi M, Yotsu-Yamashita M, Teramoto N.

Naunyn Schmiedebergs Arch Pharmacol. 2018 May;391(5):489-499. doi: 10.1007/s00210-018-1476-6. Epub 2018 Feb 16.

PMID:
29453527
11.

Six domoic acid related compounds from the red alga, Chondria armata, and domoic acid biosynthesis by the diatom, Pseudo-nitzschia multiseries.

Maeno Y, Kotaki Y, Terada R, Cho Y, Konoki K, Yotsu-Yamashita M.

Sci Rep. 2018 Jan 10;8(1):356. doi: 10.1038/s41598-017-18651-w.

12.

Total Synthesis of Polycavernosides A and B, Two Lethal Toxins from Red Alga.

Iwasaki K, Sasaki S, Kasai Y, Kawashima Y, Sasaki S, Ito T, Yotsu-Yamashita M, Sasaki M.

J Org Chem. 2017 Dec 15;82(24):13204-13219. doi: 10.1021/acs.joc.7b02293. Epub 2017 Nov 27.

PMID:
29124933
13.

Differential binding of tetrodotoxin and its derivatives to voltage-sensitive sodium channel subtypes (Nav 1.1 to Nav 1.7).

Tsukamoto T, Chiba Y, Wakamori M, Yamada T, Tsunogae S, Cho Y, Sakakibara R, Imazu T, Tokoro S, Satake Y, Adachi M, Nishikawa T, Yotsu-Yamashita M, Konoki K.

Br J Pharmacol. 2017 Nov;174(21):3881-3892. doi: 10.1111/bph.13985. Epub 2017 Sep 20.

14.

Dietary administration of tetrodotoxin and its putative biosynthetic intermediates to the captive-reared non-toxic Japanese fire-bellied newt, Cynops pyrrhogaster.

Kudo Y, Chiba C, Konoki K, Cho Y, Yotsu-Yamashita M.

Toxicon. 2017 Oct;137:78-82. doi: 10.1016/j.toxicon.2017.07.016. Epub 2017 Jul 20.

PMID:
28734983
15.

Tetrodotoxin in Asian newts (Salamandridae).

Yotsu-Yamashita M, Toennes SW, Mebs D.

Toxicon. 2017 Aug;134:14-17. doi: 10.1016/j.toxicon.2017.05.014. Epub 2017 May 17.

PMID:
28528177
16.

Synthesis and Identification of Key Biosynthetic Intermediates for the Formation of the Tricyclic Skeleton of Saxitoxin.

Tsuchiya S, Cho Y, Yoshioka R, Konoki K, Nagasawa K, Oshima Y, Yotsu-Yamashita M.

Angew Chem Int Ed Engl. 2017 May 2;56(19):5327-5331. doi: 10.1002/anie.201612461. Epub 2017 Mar 31.

PMID:
28370934
17.

Inhibition of veratridine-induced delayed inactivation of the voltage-sensitive sodium channel by synthetic analogs of crambescin B.

Tsukamoto T, Chiba Y, Nakazaki A, Ishikawa Y, Nakane Y, Cho Y, Yotsu-Yamashita M, Nishikawa T, Wakamori M, Konoki K.

Bioorg Med Chem Lett. 2017 Mar 1;27(5):1247-1251. doi: 10.1016/j.bmcl.2017.01.054. Epub 2017 Jan 19.

PMID:
28143690
18.

Column switching combined with hydrophilic interaction chromatography-tandem mass spectrometry for the analysis of saxitoxin analogues, and their biosynthetic intermediates in dinoflagellates.

Cho Y, Tsuchiya S, Yoshioka R, Omura T, Konoki K, Oshima Y, Yotsu-Yamashita M.

J Chromatogr A. 2016 Nov 25;1474:109-120. doi: 10.1016/j.chroma.2016.10.065. Epub 2016 Oct 29.

PMID:
27817832
19.

A new sarasinoside congener, sarasinoside M2, from a marine sponge collected in the Solomon Islands.

Puilingi CG, Kudo Y, Cho Y, Konoki K, Yotsu-Yamashita M.

Biosci Biotechnol Biochem. 2017 Feb;81(2):222-225. doi: 10.1080/09168451.2016.1246172. Epub 2016 Oct 20.

PMID:
27760495
20.

Diastereoselective Ring-Closing Metathesis as a Means to Construct Medium-Sized Cyclic Ethers: Application to the Synthesis of a Photoactivatable Gambierol Derivative.

Onodera Y, Hirota K, Suga Y, Konoki K, Yotsu-Yamashita M, Sasaki M, Fuwa H.

J Org Chem. 2016 Sep 16;81(18):8234-52. doi: 10.1021/acs.joc.6b01302. Epub 2016 Sep 2.

PMID:
27529493

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