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Items: 1 to 20 of 44

1.

Experimental and Theoretical Approaches in the Study of Phenanthroline-Tetrahydroquinolines for Alzheimer's Disease.

Duarte Y, Gutierrez M, Álvarez R, Alzate-Morales JH, Soto-Delgado J.

ChemistryOpen. 2019 May 21;8(5):627-636. doi: 10.1002/open.201900073. eCollection 2019 May.

2.

Bennett acceptance ratio method to calculate the binding free energy of BACE1 inhibitors: Theoretical model and design of new ligands of the enzyme.

Gutiérrez M, Vallejos GA, Cortés MP, Bustos C.

Chem Biol Drug Des. 2019 Jan 29. doi: 10.1111/cbdd.13456. [Epub ahead of print]

PMID:
30693676
3.

Synthesis of diN-Substituted Glycyl-Phenylalanine Derivatives by Using Ugi Four Component Reaction and Their Potential as Acetylcholinesterase Inhibitors.

Prent-Peñaloza L, de la Torre AF, Velázquez-Libera JL, Gutiérrez M, Caballero J.

Molecules. 2019 Jan 6;24(1). pii: E189. doi: 10.3390/molecules24010189.

4.

Personality and Emotional Intelligence in Older Adults: A Predictive Model Based on Structural Equations Modeling.

Delhom I, Gutierrez M, Lucas-Molina B, Satorres E, Meléndez JC.

J Psychol. 2019;153(2):237-246. doi: 10.1080/00223980.2018.1511516. Epub 2018 Sep 27.

PMID:
30260763
5.

Novel Alkylimidazolium Ionic Liquids as an Antibacterial Alternative to Pathogens of the Skin and Soft Tissue Infections.

Forero Doria O, Castro R, Gutierrez M, Gonzalez Valenzuela D, Santos L, Ramirez D, Guzman L.

Molecules. 2018 Sep 14;23(9). pii: E2354. doi: 10.3390/molecules23092354.

6.

Adenosine: Synthetic Methods of Its Derivatives and Antitumor Activity.

Valdés FZ, Luna VZ, Arévalo BR, Brown NV, Gutiérrez MC.

Mini Rev Med Chem. 2018;18(20):1684-1701. doi: 10.2174/1389557518666180516163539. Review.

7.

Design, facile synthesis, and evaluation of novel spiro- and pyrazolo[1,5-c]quinazolines as cholinesterase inhibitors: Molecular docking and MM/GBSA studies.

Gálvez J, Polo S, Insuasty B, Gutiérrez M, Cáceres D, Alzate-Morales JH, De-la-Torre P, Quiroga J.

Comput Biol Chem. 2018 Jun;74:218-229. doi: 10.1016/j.compbiolchem.2018.03.001. Epub 2018 Mar 7.

PMID:
29655025
8.

Synthesis of novel 7-aryl and 7-spiropyrazolo[4',3':5,6]pyrido[2,3-d]pyrimidine derivatives and their study as AChE inhibitors.

Acosta P, Insuasty B, Abonia R, Gutierrez M, Quiroga J.

Mol Divers. 2017 Nov;21(4):943-955. doi: 10.1007/s11030-017-9774-3. Epub 2017 Aug 7.

PMID:
28785929
9.

Efficient MW-Assisted Synthesis, Spectroscopic Characterization, X-ray and Antioxidant Properties of Indazole Derivatives.

Polo E, Trilleras J, Ramos J, Galdámez A, Quiroga J, Gutierrez M.

Molecules. 2016 Jul 9;21(7). pii: E903. doi: 10.3390/molecules21070903.

10.

Novel N-allyl/propargyl tetrahydroquinolines: Synthesis via Three-component Cationic Imino Diels-Alder Reaction, Binding Prediction, and Evaluation as Cholinesterase Inhibitors.

Rodríguez YA, Gutiérrez M, Ramírez D, Alzate-Morales J, Bernal CC, Güiza FM, Romero Bohórquez AR.

Chem Biol Drug Des. 2016 Oct;88(4):498-510. doi: 10.1111/cbdd.12773. Epub 2016 Jun 6.

11.

Dihydroagarofuranoid Sesquiterpenes as Acetylcholinesterase Inhibitors from Celastraceae Plants: Maytenus disticha and Euonymus japonicus.

Alarcón J, Cespedes CL, Muñoz E, Balbontin C, Valdes F, Gutierrez M, Astudillo L, Seigler DS.

J Agric Food Chem. 2015 Dec 2;63(47):10250-6. doi: 10.1021/acs.jafc.5b04168. Epub 2015 Nov 19.

PMID:
26545100
12.

Molecular Docking Studies of the Antitumoral Activity and Characterization of New Chalcone.

San-Martin A, Donoso V, Leiva S, Bacho M, Nunez S, Gutierrez M, Rovirosa J, Bailon-Moscoso N, Camacho SC, Aviles OM, Cazar ME.

Curr Top Med Chem. 2015;15(17):1743-9.

PMID:
25915607
13.

A new isoxazolic compound acts as alpha7 nicotinic receptor agonist in human umbilical vein endothelial cells.

Cortés MP, Alvarez R, Sepúlveda E, Jiménez-Aspee F, Astudillo L, Vallejos G, Gutiérrez M.

Z Naturforsch C. 2014 Jul-Aug;69(7-8):291-9.

PMID:
25265849
14.

New diterpenes from Azorella spinosa.

Astudillo L, Gutiérrez M, Quesada L, San-Martín A, Espinoza L, Peñailillo P.

Nat Prod Commun. 2014 Jan;9(1):9-12.

PMID:
24660449
15.

Ultrasound-assisted phase-transfer catalysis method in an aqueous medium to promote the Knoevenagel reaction: advantages over the conventional and microwave-assisted solvent-free/catalyst-free method.

De-la-Torre P, Osorio E, Alzate-Morales JH, Caballero J, Trilleras J, Astudillo-Saavedra L, Brito I, Cárdenas A, Quiroga J, Gutiérrez M.

Ultrason Sonochem. 2014 Sep;21(5):1666-74. doi: 10.1016/j.ultsonch.2014.02.021. Epub 2014 Mar 1.

PMID:
24650611
16.

Effect of tomato industrial processing (different hybrids, paste, and pomace) on inhibition of platelet function in vitro, ex vivo, and in vivo.

Rodríguez-Azúa R, Treuer A, Moore-Carrasco R, Cortacáns D, Gutiérrez M, Astudillo L, Fuentes E, Palomo I.

J Med Food. 2014 Apr;17(4):505-11. doi: 10.1089/jmf.2012.0243. Epub 2013 Dec 10.

17.

Isoxazoles: synthesis, evaluation and bioinformatic design as acetylcholinesterase inhibitors.

Gutiérrez M, Matus MF, Poblete T, Amigo J, Vallejos G, Astudillo L.

J Pharm Pharmacol. 2013 Dec;65(12):1796-804. doi: 10.1111/jphp.12180. Epub 2013 Nov 4.

PMID:
24180424
18.

Synthesis of bistetrahydroquinolines as potential anticholinesterasic agents by double Diels-Alder reactions.

Duarte Y, Gutiérrez M, Astudillo L, Alzate-Morales J, Valdés N.

Molecules. 2013 Oct 17;18(10):12951-65. doi: 10.3390/molecules181012951.

19.

Protective mechanisms of guanosine from Solanum lycopersicum on agonist-induced platelet activation: role of sCD40L.

Fuentes E, Alarcón M, Astudillo L, Valenzuela C, Gutiérrez M, Palomo I.

Molecules. 2013 Jul 10;18(7):8120-35. doi: 10.3390/molecules18078120.

20.

Synthetic isoxazole as antiplatelet agent.

Gutiérrez M, Amigo J, Fuentes E, Palomo I, Astudillo L.

Platelets. 2014;25(4):234-8. doi: 10.3109/09537104.2013.807335. Epub 2013 Jul 10.

PMID:
23841686

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