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Items: 1 to 20 of 24

1.

Inhibition of Bromodomain and Extraterminal Domain (BET) Proteins by JQ1 Unravels a Novel Epigenetic Modulation to Control Lipid Homeostasis.

Tonini C, Colardo M, Colella B, Di Bartolomeo S, Berardinelli F, Caretti G, Pallottini V, Segatto M.

Int J Mol Sci. 2020 Feb 14;21(4). pii: E1297. doi: 10.3390/ijms21041297.

2.

Long-lasting impact of perinatal dietary supplementation of omega 3 fatty acids on mevalonate pathway: potential role on neuron trophism in male offspring hippocampal formation.

Tonini C, Schiavi S, Macca F, Segatto M, Trezza V, Pallottini V.

Nutr Neurosci. 2020 Feb 9:1-12. doi: 10.1080/1028415X.2020.1724452. [Epub ahead of print]

PMID:
32037984
3.

Evaluation of IL8 pathway on the ocular surface: new insights in patients with ocular mucous membrane pemphigoid.

Bruscolini A, Lambiase A, Segatto M, La Cava M, Nebbioso M, Sacchetti M.

Acta Ophthalmol. 2020 Mar;98(2):e173-e177. doi: 10.1111/aos.14240. Epub 2019 Sep 5.

PMID:
31486595
4.

Loss of Mevalonate/Cholesterol Homeostasis in the Brain: A Focus on Autism Spectrum Disorder and Rett Syndrome.

Segatto M, Tonini C, Pfrieger FW, Trezza V, Pallottini V.

Int J Mol Sci. 2019 Jul 5;20(13). pii: E3317. doi: 10.3390/ijms20133317. Review.

5.

Unidirectional opioid-cannabinoid cross-tolerance in the modulation of social play behavior in rats.

Schiavi S, Manduca A, Segatto M, Campolongo P, Pallottini V, Vanderschuren LJMJ, Trezza V.

Psychopharmacology (Berl). 2019 Sep;236(9):2557-2568. doi: 10.1007/s00213-019-05226-y. Epub 2019 Mar 22.

PMID:
30903212
6.

VEGF inhibition alters neurotrophin signalling pathways and induces caspase-3 activation and autophagy in rabbit retina.

Segatto M, Fico E, Gharbiya M, Rosso P, Carito V, Tirassa P, Plateroti R, Lambiase A.

J Cell Physiol. 2019 Aug;234(10):18297-18307. doi: 10.1002/jcp.28462. Epub 2019 Mar 19.

PMID:
30891770
7.

Changes of NGF pathway in allergic rhinoconjunctivitis: A conjunctival allergen challenge study.

Sacchetti M, Segatto M, Bruscolini A, Abicca I, Cavaliere C, Lambiase A.

Allergy. 2019 Mar;74(3):605-607. doi: 10.1111/all.13641. Epub 2018 Nov 12. No abstract available.

PMID:
30353971
8.

In vivo antivascular endothelial growth factor treatment induces corneal endothelium apoptosis in rabbits through changes in p75NTR-proNGF pathway.

Gharbiya M, Bruscolini A, Sacchetti M, Rosso P, Carito V, Segatto M, Fico E, Tirassa P, Lambiase A.

J Cell Physiol. 2018 Nov;233(11):8874-8883. doi: 10.1002/jcp.26806. Epub 2018 Jun 1.

PMID:
29856479
9.

Altered Brain Cholesterol/Isoprenoid Metabolism in a Rat Model of Autism Spectrum Disorders.

Cartocci V, Catallo M, Tempestilli M, Segatto M, Pfrieger FW, Bronzuoli MR, Scuderi C, Servadio M, Trezza V, Pallottini V.

Neuroscience. 2018 Feb 21;372:27-37. doi: 10.1016/j.neuroscience.2017.12.053. Epub 2018 Jan 6.

PMID:
29309878
10.

Epigenetic targeting of bromodomain protein BRD4 counteracts cancer cachexia and prolongs survival.

Segatto M, Fittipaldi R, Pin F, Sartori R, Dae Ko K, Zare H, Fenizia C, Zanchettin G, Pierobon ES, Hatakeyama S, Sperti C, Merigliano S, Sandri M, Filippakopoulos P, Costelli P, Sartorelli V, Caretti G.

Nat Commun. 2017 Nov 22;8(1):1707. doi: 10.1038/s41467-017-01645-7.

11.

Statins and the Brain: More than Lipid Lowering Agents?

Fracassi A, Marangoni M, Rosso P, Pallottini V, Fioramonti M, Siteni S, Segatto M.

Curr Neuropharmacol. 2019;17(1):59-83. doi: 10.2174/1570159X15666170703101816. Review.

12.

Modulation of the Isoprenoid/Cholesterol Biosynthetic Pathway During Neuronal Differentiation In Vitro.

Cartocci V, Segatto M, Di Tunno I, Leone S, Pfrieger FW, Pallottini V.

J Cell Biochem. 2016 Sep;117(9):2036-44. doi: 10.1002/jcb.25500. Epub 2016 Feb 5.

PMID:
27392312
13.

Estrogen receptor α L429 and A430 regulate 17β-estradiol-induced cell proliferation via CREB1.

Pesiri V, Totta P, Segatto M, Bianchi F, Pallottini V, Marino M, Acconcia F.

Cell Signal. 2015 Dec;27(12):2380-8. doi: 10.1016/j.cellsig.2015.08.021. Epub 2015 Sep 5.

PMID:
26348925
14.

Cholesterol metabolism is altered in Rett syndrome: a study on plasma and primary cultured fibroblasts derived from patients.

Segatto M, Trapani L, Di Tunno I, Sticozzi C, Valacchi G, Hayek J, Pallottini V.

PLoS One. 2014 Aug 12;9(8):e104834. doi: 10.1371/journal.pone.0104834. eCollection 2014. Erratum in: PLoS One. 2014;9(11):e114654.

15.

Cholesterol homeostasis failure in the brain: implications for synaptic dysfunction and cognitive decline.

Segatto M, Leboffe L, Trapani L, Pallottini V.

Curr Med Chem. 2014;21(24):2788-802. Review.

PMID:
24606521
16.

New compounds able to control hepatic cholesterol metabolism: Is it possible to avoid statin treatment in aged people?

Trapani L, Segatto M, Pallottini V.

World J Hepatol. 2013 Dec 27;5(12):676-84. doi: 10.4254/wjh.v5.i12.676. Review.

17.

Simvastatin treatment highlights a new role for the isoprenoid/cholesterol biosynthetic pathway in the modulation of emotional reactivity and cognitive performance in rats.

Segatto M, Manduca A, Lecis C, Rosso P, Jozwiak A, Swiezewska E, Moreno S, Trezza V, Pallottini V.

Neuropsychopharmacology. 2014 Mar;39(4):841-54. doi: 10.1038/npp.2013.284. Epub 2013 Oct 10.

18.

Analysis of the protein network of cholesterol homeostasis in different brain regions: an age and sex dependent perspective.

Segatto M, Di Giovanni A, Marino M, Pallottini V.

J Cell Physiol. 2013 Jul;228(7):1561-7. doi: 10.1002/jcp.24315.

PMID:
23280554
19.

Regulation and deregulation of cholesterol homeostasis: The liver as a metabolic "power station".

Trapani L, Segatto M, Pallottini V.

World J Hepatol. 2012 Jun 27;4(6):184-90. doi: 10.4254/wjh.v4.i6.184.

20.

3-hydroxy 3-methylglutaryl coenzyme A reductase inhibition impairs muscle regeneration.

Trapani L, Segatto M, La Rosa P, Fanelli F, Moreno S, Marino M, Pallottini V.

J Cell Biochem. 2012 Jun;113(6):2057-63. doi: 10.1002/jcb.24077.

PMID:
22274883

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