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Items: 1 to 20 of 62


Identification of Potential Virulence Factors in the Model Strain Acinetobacter baumannii A118.

Ramirez MS, Penwell WF, Traglia GM, Zimbler DL, Gaddy JA, Nikolaidis N, Arivett BA, Adams MD, Bonomo RA, Actis LA, Tolmasky ME.

Front Microbiol. 2019 Jul 23;10:1599. doi: 10.3389/fmicb.2019.01599. eCollection 2019.


Bridged Nucleic Acids Reloaded.

Soler-Bistué A, Zorreguieta A, Tolmasky ME.

Molecules. 2019 Jun 21;24(12). pii: E2297. doi: 10.3390/molecules24122297. Review.


Restoration of susceptibility to amikacin by 8-hydroxyquinoline analogs complexed to zinc.

Magallon J, Chiem K, Tran T, Ramirez MS, Jimenez V, Tolmasky ME.

PLoS One. 2019 May 29;14(5):e0217602. doi: 10.1371/journal.pone.0217602. eCollection 2019.


Interspecies DNA acquisition by a naturally competent Acinetobacter baumannii strain.

Traglia GM, Place K, Dotto C, Fernandez JS, Montaña S, Bahiense CDS, Soler-Bistue A, Iriarte A, Perez F, Tolmasky ME, Bonomo RA, Melano RG, Ramírez MS.

Int J Antimicrob Agents. 2019 Apr;53(4):483-490. doi: 10.1016/j.ijantimicag.2018.12.013. Epub 2019 Jan 3.


Genome sequence analysis of an extensively drug-resistant Acinetobacter baumannii indigo-pigmented strain depicts evidence of increase genome plasticity.

Traglia G, Chiem K, Quinn B, Fernandez JS, Montaña S, Almuzara M, Mussi MA, Tolmasky ME, Iriarte A, Centrón D, Ramírez MS.

Sci Rep. 2018 Nov 16;8(1):16961. doi: 10.1038/s41598-018-35377-5.


Identification of the Acinetobacter baumannii Ribonuclease P Catalytic Subunit: Cleavage of a Target mRNA in the Presence of an External Guide Sequence.

Davies-Sala C, Jani S, Zorreguieta A, Tolmasky ME.

Front Microbiol. 2018 Oct 8;9:2408. doi: 10.3389/fmicb.2018.02408. eCollection 2018.


Assessment of External Guide Sequences' (EGS) Efficiency as Inducers of RNase P-Mediated Cleavage of mRNA Target Molecules.

Jani S, Jackson A, Davies-Sala C, Chiem K, Soler-Bistué A, Zorreguieta A, Tolmasky ME.

Methods Mol Biol. 2018;1737:89-98. doi: 10.1007/978-1-4939-7634-8_6.


Identification of a small molecule inhibitor of the aminoglycoside 6'-N-acetyltransferase type Ib [AAC(6')-Ib] using mixture-based combinatorial libraries.

Tran T, Chiem K, Jani S, Arivett BA, Lin DL, Lad R, Jimenez V, Farone MB, Debevec G, Santos R, Giulianotti M, Pinilla C, Tolmasky ME.

Int J Antimicrob Agents. 2018 May;51(5):752-761. doi: 10.1016/j.ijantimicag.2018.01.019. Epub 2018 Feb 2.


Amikacin: Uses, Resistance, and Prospects for Inhibition.

Ramirez MS, Tolmasky ME.

Molecules. 2017 Dec 19;22(12). pii: E2267. doi: 10.3390/molecules22122267. Review.


Evaluation of the electron transfer flavoprotein as an antibacterial target in Burkholderia cenocepacia.

Stietz MS, Lopez C, Osifo O, Tolmasky ME, Cardona ST.

Can J Microbiol. 2017 Oct;63(10):857-863. doi: 10.1139/cjm-2017-0350. Epub 2017 Aug 17.


Inhibition of aminoglycoside 6'-N-acetyltransferase type Ib-mediated amikacin resistance by zinc complexed with clioquinol, an ionophore active against tumors and neurodegenerative diseases.

Chiem K, Hue F, Magallon J, Tolmasky ME.

Int J Antimicrob Agents. 2018 Feb;51(2):271-273. doi: 10.1016/j.ijantimicag.2017.08.002. Epub 2017 Aug 3. No abstract available.


Assessment of configurations and chemistries of bridged nucleic acids-containing oligomers as external guide sequences: a methodology for inhibition of expression of antibiotic resistance genes.

Jackson A, Jani S, Sala CD, Soler-Bistué AJ, Zorreguieta A, Tolmasky ME.

Biol Methods Protoc. 2016 Mar;1(1). pii: bpw001. Epub 2016 Mar 1.


The Genetic Analysis of an Acinetobacter johnsonii Clinical Strain Evidenced the Presence of Horizontal Genetic Transfer.

Montaña S, Schramm ST, Traglia GM, Chiem K, Parmeciano Di Noto G, Almuzara M, Barberis C, Vay C, Quiroga C, Tolmasky ME, Iriarte A, Ramírez MS.

PLoS One. 2016 Aug 22;11(8):e0161528. doi: 10.1371/journal.pone.0161528. eCollection 2016.


Whole-Genome Comparative Analysis of Two Carbapenem-Resistant ST-258 Klebsiella pneumoniae Strains Isolated during a North-Eastern Ohio Outbreak: Differences within the High Heterogeneity Zones.

Ramirez MS, Xie G, Traglia GM, Johnson SL, Davenport KW, van Duin D, Ramazani A, Perez F, Jacobs MR, Sherratt DJ, Bonomo RA, Chain PS, Tolmasky ME.

Genome Biol Evol. 2016 Jul 3;8(6):2036-43. doi: 10.1093/gbe/evw135.


Identification of an Inhibitor of the Aminoglycoside 6'-N-Acetyltransferase type Ib [AAC(6')-Ib] by Glide Molecular Docking.

Chiem K, Jani S, Fuentes B, Lin DL, Rasche ME, Tolmasky ME.

Medchemcomm. 2016 Jan 1;7(1):184-189. Epub 2015 Nov 3.


Inhibition of AAC(6')-Ib-mediated resistance to amikacin in Acinetobacter baumannii by an antisense peptide-conjugated 2',4'-bridged nucleic acid-NC-DNA hybrid oligomer.

Lopez C, Arivett BA, Actis LA, Tolmasky ME.

Antimicrob Agents Chemother. 2015 Sep;59(9):5798-803. doi: 10.1128/AAC.01304-15. Epub 2015 Jul 13.


Inhibition of aminoglycoside 6'-N-acetyltransferase type Ib-mediated amikacin resistance in Klebsiella pneumoniae by zinc and copper pyrithione.

Chiem K, Fuentes BA, Lin DL, Tran T, Jackson A, Ramirez MS, Tolmasky ME.

Antimicrob Agents Chemother. 2015 Sep;59(9):5851-3. doi: 10.1128/AAC.01106-15. Epub 2015 Jul 13.


Plasmid-Mediated Antibiotic Resistance and Virulence in Gram-Negatives: the Klebsiella pneumoniae Paradigm.

Ramirez MS, Traglia GM, Lin DL, Tran T, Tolmasky ME.

Microbiol Spectr. 2014 Oct;2(5). doi: 10.1128/microbiolspec.PLAS-0016-2013. Review.


External guide sequence technology: a path to development of novel antimicrobial therapeutics.

Davies-Sala C, Soler-Bistué A, Bonomo RA, Zorreguieta A, Tolmasky ME.

Ann N Y Acad Sci. 2015 Sep;1354:98-110. doi: 10.1111/nyas.12755. Epub 2015 Apr 9. Review.


Draft Genome Sequence of Empedobacter (Formerly Wautersiella) falsenii comb. nov. Wf282, a Strain Isolated from a Cervical Neck Abscess.

Traglia GM, Dixon C, Chiem K, Almuzara M, Barberis C, Montaña S, Merino C, Mussi MA, Tolmasky ME, Iriarte A, Vay C, Ramírez MS.

Genome Announc. 2015 Apr 2;3(2). pii: e00235-15. doi: 10.1128/genomeA.00235-15.

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