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Items: 1 to 20 of 117

1.

The Peptide ERα17p Is a GPER Inverse Agonist that Exerts Antiproliferative Effects in Breast Cancer Cells.

Lappano R, Mallet C, Rizzuti B, Grande F, Galli GR, Byrne C, Broutin I, Boudieu L, Eschalier A, Jacquot Y, Maggiolini M.

Cells. 2019 Jun 14;8(6). pii: E590. doi: 10.3390/cells8060590.

2.

Differential MicroRNA Landscape Triggered by Estrogens in Cancer Associated Fibroblasts (CAFs) of Primary and Metastatic Breast Tumors.

Vivacqua A, Muoio MG, Miglietta AM, Maggiolini M.

Cancers (Basel). 2019 Mar 23;11(3). pii: E412. doi: 10.3390/cancers11030412.

3.

GPER Mediates a Feedforward FGF2/FGFR1 Paracrine Activation Coupling CAFs to Cancer Cells toward Breast Tumor Progression.

Santolla MF, Vivacqua A, Lappano R, Rigiracciolo DC, Cirillo F, Galli GR, Talia M, Brunetti G, Miglietta AM, Belfiore A, Maggiolini M.

Cells. 2019 Mar 7;8(3). pii: E223. doi: 10.3390/cells8030223.

4.

A Platform of Synthetic Lethal Gene Interaction Networks Reveals that the GNAQ Uveal Melanoma Oncogene Controls the Hippo Pathway through FAK.

Feng X, Arang N, Rigiracciolo DC, Lee JS, Yeerna H, Wang Z, Lubrano S, Kishore A, Pachter JA, König GM, Maggiolini M, Kostenis E, Schlaepfer DD, Tamayo P, Chen Q, Ruppin E, Gutkind JS.

Cancer Cell. 2019 Mar 18;35(3):457-472.e5. doi: 10.1016/j.ccell.2019.01.009. Epub 2019 Feb 14.

PMID:
30773340
5.

Focal adhesion kinase (FAK) activation by estrogens involves GPER in triple-negative breast cancer cells.

Rigiracciolo DC, Santolla MF, Lappano R, Vivacqua A, Cirillo F, Galli GR, Talia M, Muglia L, Pellegrino M, Nohata N, Di Martino MT, Maggiolini M.

J Exp Clin Cancer Res. 2019 Feb 6;38(1):58. doi: 10.1186/s13046-019-1056-8.

6.

GPCR Modulation in Breast Cancer.

Lappano R, Jacquot Y, Maggiolini M.

Int J Mol Sci. 2018 Dec 2;19(12). pii: E3840. doi: 10.3390/ijms19123840. Review.

7.

miR-338-3p Is Regulated by Estrogens through GPER in Breast Cancer Cells and Cancer-Associated Fibroblasts (CAFs).

Vivacqua A, Sebastiani A, Miglietta AM, Rigiracciolo DC, Cirillo F, Galli GR, Talia M, Santolla MF, Lappano R, Giordano F, Panno ML, Maggiolini M.

Cells. 2018 Nov 9;7(11). pii: E203. doi: 10.3390/cells7110203.

8.

Crosstalk between Notch, HIF-1α and GPER in Breast Cancer EMT.

De Francesco EM, Maggiolini M, Musti AM.

Int J Mol Sci. 2018 Jul 10;19(7). pii: E2011. doi: 10.3390/ijms19072011. Review.

9.

Functional characterization of the partially purified Sac1p independent adenine nucleotide transport system (ANTS) from yeast endoplasmic reticulum.

Li Y, Cappello AR, Muto L, Martello E, Madeo M, Curcio R, Lunetti P, Raho S, Zaffino F, Frattaruolo L, Lappano R, Malivindi R, Maggiolini M, Aiello D, Piazzolla C, Capobianco L, Fiermonte G, Dolce V.

J Biochem. 2018 Oct 1;164(4):313-322. doi: 10.1093/jb/mvy054.

PMID:
29893873
10.

Notch1 Mediates Preconditioning Protection Induced by GPER in Normotensive and Hypertensive Female Rat Hearts.

Rocca C, Femminò S, Aquila G, Granieri MC, De Francesco EM, Pasqua T, Rigiracciolo DC, Fortini F, Cerra MC, Maggiolini M, Pagliaro P, Rizzo P, Angelone T, Penna C.

Front Physiol. 2018 May 15;9:521. doi: 10.3389/fphys.2018.00521. eCollection 2018.

11.

The Physiopathological Role of the Exchangers Belonging to the SLC37 Family.

Cappello AR, Curcio R, Lappano R, Maggiolini M, Dolce V.

Front Chem. 2018 Apr 17;6:122. doi: 10.3389/fchem.2018.00122. eCollection 2018. Review.

12.

miR-221 stimulates breast cancer cells and cancer-associated fibroblasts (CAFs) through selective interference with the A20/c-Rel/CTGF signaling.

Santolla MF, Lappano R, Cirillo F, Rigiracciolo DC, Sebastiani A, Abonante S, Tassone P, Tagliaferri P, Di Martino MT, Maggiolini M, Vivacqua A.

J Exp Clin Cancer Res. 2018 May 2;37(1):94. doi: 10.1186/s13046-018-0767-6.

13.

GPER is involved in the regulation of the estrogen-metabolizing CYP1B1 enzyme in breast cancer.

Cirillo F, Pellegrino M, Malivindi R, Rago V, Avino S, Muto L, Dolce V, Vivacqua A, Rigiracciolo DC, De Marco P, Sebastiani A, Abonante S, Nakajima M, Lappano R, Maggiolini M.

Oncotarget. 2017 Nov 20;8(63):106608-106624. doi: 10.18632/oncotarget.22541. eCollection 2017 Dec 5.

14.

G Protein-Coupled Receptors at the Crossroad between Physiologic and Pathologic Angiogenesis: Old Paradigms and Emerging Concepts.

De Francesco EM, Sotgia F, Clarke RB, Lisanti MP, Maggiolini M.

Int J Mol Sci. 2017 Dec 14;18(12). pii: E2713. doi: 10.3390/ijms18122713. Review.

15.

GPER mediates the angiocrine actions induced by IGF1 through the HIF-1α/VEGF pathway in the breast tumor microenvironment.

De Francesco EM, Sims AH, Maggiolini M, Sotgia F, Lisanti MP, Clarke RB.

Breast Cancer Res. 2017 Dec 6;19(1):129. doi: 10.1186/s13058-017-0923-5.

16.

Vitamin C and Doxycycline: A synthetic lethal combination therapy targeting metabolic flexibility in cancer stem cells (CSCs).

De Francesco EM, Bonuccelli G, Maggiolini M, Sotgia F, Lisanti MP.

Oncotarget. 2017 Jun 9;8(40):67269-67286. doi: 10.18632/oncotarget.18428. eCollection 2017 Sep 15.

17.

The lauric acid-activated signaling prompts apoptosis in cancer cells.

Lappano R, Sebastiani A, Cirillo F, Rigiracciolo DC, Galli GR, Curcio R, Malaguarnera R, Belfiore A, Cappello AR, Maggiolini M.

Cell Death Discov. 2017 Sep 18;3:17063. doi: 10.1038/cddiscovery.2017.63. eCollection 2017.

18.

Targeting hypoxic cancer stem cells (CSCs) with Doxycycline: Implications for optimizing anti-angiogenic therapy.

De Francesco EM, Maggiolini M, Tanowitz HB, Sotgia F, Lisanti MP.

Oncotarget. 2017 Jun 12;8(34):56126-56142. doi: 10.18632/oncotarget.18445. eCollection 2017 Aug 22.

19.

Recent Advances on the Role of microRNAs in both Insulin Resistance and Cancer.

Vivacqua A, De Marco P, Belfiore A, Maggiolini M.

Curr Pharm Des. 2017;23(25):3658-3666. doi: 10.2174/1381612823666170622105123. Review.

PMID:
28641547
20.

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