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Items: 1 to 20 of 32


EXOSC10 is required for RPA assembly and controlled DNA end resection at DNA double-strand breaks.

Domingo-Prim J, Endara-Coll M, Bonath F, Jimeno S, Prados-Carvajal R, Friedländer MR, Huertas P, Visa N.

Nat Commun. 2019 May 13;10(1):2135. doi: 10.1038/s41467-019-10153-9.


Evolutionary Implications of the microRNA- and piRNA Complement of Lepidodermella squamata (Gastrotricha).

Fromm B, Tosar JP, Aguilera F, Friedländer MR, Bachmann L, Hejnol A.

Noncoding RNA. 2019 Feb 22;5(1). pii: E19. doi: 10.3390/ncrna5010019.


The Circulating Transcriptome as a Source of Biomarkers for Melanoma.

Solé C, Tramonti D, Schramm M, Goicoechea I, Armesto M, Hernandez LI, Manterola L, Fernandez-Mercado M, Mujika K, Tuneu A, Jaka A, Tellaetxe M, Friedländer MR, Estivill X, Piazza P, Ortiz-Romero PL, Middleton MR, Lawrie CH.

Cancers (Basel). 2019 Jan 10;11(1). pii: E70. doi: 10.3390/cancers11010070.


miRTrace reveals the organismal origins of microRNA sequencing data.

Kang W, Eldfjell Y, Fromm B, Estivill X, Biryukova I, Friedländer MR.

Genome Biol. 2018 Dec 4;19(1):213. doi: 10.1186/s13059-018-1588-9.


Next-generation sequencing reveals two populations of damage-induced small RNAs at endogenous DNA double-strand breaks.

Bonath F, Domingo-Prim J, Tarbier M, Friedländer MR, Visa N.

Nucleic Acids Res. 2018 Dec 14;46(22):11869-11882. doi: 10.1093/nar/gky1107.


Control of hepatic gluconeogenesis by Argonaute2.

Yan X, Wang Z, Bishop CA, Weitkunat K, Feng X, Tarbier M, Luo J, Friedländer MR, Burkhardt R, Klaus S, Willnow TE, Poy MN.

Mol Metab. 2018 Dec;18:15-24. doi: 10.1016/j.molmet.2018.10.003. Epub 2018 Oct 9.


Plant microRNAs in human sera are likely contaminants.

Fromm B, Kang W, Rovira C, Cayota A, Witwer K, Friedländer MR, Tosar JP.

J Nutr Biochem. 2019 Mar;65:139-140. doi: 10.1016/j.jnutbio.2018.07.019. Epub 2018 Sep 5. No abstract available.


microRNA-205-5p is a modulator of insulin sensitivity that inhibits FOXO function.

Langlet F, Tarbier M, Haeusler RA, Camastra S, Ferrannini E, Friedländer MR, Accili D.

Mol Metab. 2018 Nov;17:49-60. doi: 10.1016/j.molmet.2018.08.003. Epub 2018 Aug 11.


Signatures of positive selection reveal a universal role of chromatin modifiers as cancer driver genes.

Zapata L, Susak H, Drechsel O, Friedländer MR, Estivill X, Ossowski S.

Sci Rep. 2017 Oct 13;7(1):13124. doi: 10.1038/s41598-017-12888-1.


Differential Impact of Glucose Administered Intravenously and Orally on Circulating miR-375 Levels in Human Subjects.

Yan X, Wang Z, Westberg-Rasmussen S, Tarbier M, Rathjen T, Tattikota SG, Peck BCE, Kanke M, Oxvig C, Frystyk J, Starup-Linde J, Sethupathy P, Friedländer MR, Gregersen S, Poy MN.

J Clin Endocrinol Metab. 2017 Oct 1;102(10):3749-3755. doi: 10.1210/jc.2017-01365.


The acute effects of ultraviolet radiation on the blood transcriptome are independent of plasma 25OHD3.

Bustamante M, Hernandez-Ferrer C, Sarria Y, Harrison GI, Nonell L, Kang W, Friedländer MR, Estivill X, González JR, Nieuwenhuijsen M, Young AR.

Environ Res. 2017 Nov;159:239-248. doi: 10.1016/j.envres.2017.07.045. Epub 2017 Sep 18.


A Fluorophore Fusion Construct of Human Profilin I with Non-Compromised Poly(L-Proline) Binding Capacity Suitable for Imaging.

Nejedla M, Li Z, Masser AE, Biancospino M, Spiess M, Mackowiak SD, Friedländer MR, Karlsson R.

J Mol Biol. 2017 Apr 7;429(7):964-976. doi: 10.1016/j.jmb.2017.01.004. Epub 2017 Jan 8.


Survey of 800+ data sets from human tissue and body fluid reveals xenomiRs are likely artifacts.

Kang W, Bang-Berthelsen CH, Holm A, Houben AJ, Müller AH, Thymann T, Pociot F, Estivill X, Friedländer MR.

RNA. 2017 Apr;23(4):433-445. doi: 10.1261/rna.059725.116. Epub 2017 Jan 6.


Sequence variation between 462 human individuals fine-tunes functional sites of RNA processing.

Ferreira PG, Oti M, Barann M, Wieland T, Ezquina S, Friedländer MR, Rivas MA, Esteve-Codina A; GEUVADIS Consortium, Rosenstiel P, Strom TM, Lappalainen T, Guigó R, Sammeth M.

Sci Rep. 2016 Sep 12;6:32406. doi: 10.1038/srep32406.


Cytosolic splice isoform of Hsp70 nucleotide exchange factor Fes1 is required for the degradation of misfolded proteins in yeast.

Gowda NK, Kaimal JM, Masser AE, Kang W, Friedländer MR, Andréasson C.

Mol Biol Cell. 2016 Apr 15;27(8):1210-9. doi: 10.1091/mbc.E15-10-0697. Epub 2016 Feb 24.


Specific small-RNA signatures in the amygdala at premotor and motor stages of Parkinson's disease revealed by deep sequencing analysis.

Pantano L, Friedländer MR, Escaramís G, Lizano E, Pallarès-Albanell J, Ferrer I, Estivill X, Martí E.

Bioinformatics. 2016 Mar 1;32(5):673-81. doi: 10.1093/bioinformatics/btv632. Epub 2015 Nov 2.


miR-184 Regulates Pancreatic β-Cell Function According to Glucose Metabolism.

Tattikota SG, Rathjen T, Hausser J, Khedkar A, Kabra UD, Pandey V, Sury M, Wessels HH, Mollet IG, Eliasson L, Selbach M, Zinzen RP, Zavolan M, Kadener S, Tschöp MH, Jastroch M, Friedländer MR, Poy MN.

J Biol Chem. 2015 Aug 14;290(33):20284-94. doi: 10.1074/jbc.M115.658625. Epub 2015 Jul 7.


Human genomics. Effect of predicted protein-truncating genetic variants on the human transcriptome.

Rivas MA, Pirinen M, Conrad DF, Lek M, Tsang EK, Karczewski KJ, Maller JB, Kukurba KR, DeLuca DS, Fromer M, Ferreira PG, Smith KS, Zhang R, Zhao F, Banks E, Poplin R, Ruderfer DM, Purcell SM, Tukiainen T, Minikel EV, Stenson PD, Cooper DN, Huang KH, Sullivan TJ, Nedzel J; GTEx Consortium; Geuvadis Consortium, Bustamante CD, Li JB, Daly MJ, Guigo R, Donnelly P, Ardlie K, Sammeth M, Dermitzakis ET, McCarthy MI, Montgomery SB, Lappalainen T, MacArthur DG.

Science. 2015 May 8;348(6235):666-9. doi: 10.1126/science.1261877.


Computational Prediction of miRNA Genes from Small RNA Sequencing Data.

Kang W, Friedländer MR.

Front Bioeng Biotechnol. 2015 Jan 26;3:7. doi: 10.3389/fbioe.2015.00007. eCollection 2015. Review.


Tandem RNA chimeras contribute to transcriptome diversity in human population and are associated with intronic genetic variants.

Greger L, Su J, Rung J, Ferreira PG; Geuvadis consortium, Lappalainen T, Dermitzakis ET, Brazma A.

PLoS One. 2014 Aug 18;9(8):e104567. doi: 10.1371/journal.pone.0104567. eCollection 2014.

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