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Items: 1 to 20 of 41


Targeting the delivery of dietary plant bioactives to those who would benefit most: from science to practical applications.

de Roos B, Aura AM, Bronze M, Cassidy A, Conesa MG, Gibney ER, Greyling A, Kaput J, Kerem Z, Knežević N, Kroon P, Landberg R, Manach C, Milenkovic D, Rodriguez-Mateos A, Tomás-Barberán FA, van de Wiele T, Morand C.

Eur J Nutr. 2019 Nov;58(Suppl 2):65-73. doi: 10.1007/s00394-019-02075-5. Epub 2019 Oct 22. Review.


The inhibitory effect of flavonoids and their gut-derived metabolites on the replication of Chlamydia abortus in the AH-1 ovine trophoblast cell line.

Del Río L, Salinas J, Buendía AJ, García-Conesa MT.

Res Vet Sci. 2019 Oct;126:199-206. doi: 10.1016/j.rvsc.2019.09.006. Epub 2019 Sep 12.


Chokeberry Juice Containing Polyphenols Does Not Affect Cholesterol or Blood Pressure but Modifies the Composition of Plasma Phospholipids Fatty Acids in Individuals at Cardiovascular Risk.

Pokimica B, García-Conesa MT, Zec M, Debeljak-Martačić J, Ranković S, Vidović N, Petrović-Oggiano G, Konić-Ristić A, Glibetić M.

Nutrients. 2019 Apr 15;11(4). pii: E850. doi: 10.3390/nu11040850.


An Exploratory Search for Potential Molecular Targets Responsive to the Probiotic Lactobacillus salivarius PS2 in Women With Mastitis: Gene Expression Profiling vs. Interindividual Variability.

de Andrés J, Jiménez E, Espinosa-Martos I, Rodríguez JM, García-Conesa MT.

Front Microbiol. 2018 Sep 13;9:2166. doi: 10.3389/fmicb.2018.02166. eCollection 2018.


Meta-Analysis of the Effects of Foods and Derived Products Containing Ellagitannins and Anthocyanins on Cardiometabolic Biomarkers: Analysis of Factors Influencing Variability of the Individual Responses.

García-Conesa MT, Chambers K, Combet E, Pinto P, Garcia-Aloy M, Andrés-Lacueva C, de Pascual-Teresa S, Mena P, Konic Ristic A, Hollands WJ, Kroon PA, Rodríguez-Mateos A, Istas G, Kontogiorgis CA, Rai DK, Gibney ER, Morand C, Espín JC, González-Sarrías A.

Int J Mol Sci. 2018 Feb 28;19(3). pii: E694. doi: 10.3390/ijms19030694. Review.


Gene expression changes in colon tissues from colorectal cancer patients following the intake of an ellagitannin-containing pomegranate extract: a randomized clinical trial.

Nuñez-Sánchez MA, González-Sarrías A, García-Villalba R, Monedero-Saiz T, García-Talavera NV, Gómez-Sánchez MB, Sánchez-Álvarez C, García-Albert AM, Rodríguez-Gil FJ, Ruiz-Marín M, Pastor-Quirante FA, Martínez-Díaz F, Tomás-Barberán FA, Espín JC, García-Conesa MT.

J Nutr Biochem. 2017 Apr;42:126-133. doi: 10.1016/j.jnutbio.2017.01.014. Epub 2017 Jan 27.


Addressing the inter-individual variation in response to consumption of plant food bioactives: Towards a better understanding of their role in healthy aging and cardiometabolic risk reduction.

Manach C, Milenkovic D, Van de Wiele T, Rodriguez-Mateos A, de Roos B, Garcia-Conesa MT, Landberg R, Gibney ER, Heinonen M, Tomás-Barberán F, Morand C.

Mol Nutr Food Res. 2017 Jun;61(6). doi: 10.1002/mnfr.201600557. Epub 2016 Nov 15. Review.


In vivo relevant mixed urolithins and ellagic acid inhibit phenotypic and molecular colon cancer stem cell features: A new potentiality for ellagitannin metabolites against cancer.

Núñez-Sánchez MÁ, Karmokar A, González-Sarrías A, García-Villalba R, Tomás-Barberán FA, García-Conesa MT, Brown K, Espín JC.

Food Chem Toxicol. 2016 Jun;92:8-16. doi: 10.1016/j.fct.2016.03.011. Epub 2016 Mar 16.


Targeted and Untargeted Metabolomics to Explore the Bioavailability of the Secoiridoids from a Seed/Fruit Extract (Fraxinus angustifolia Vahl) in Human Healthy Volunteers: A Preliminary Study.

García-Villalba R, Tomás-Barberán FA, Fança-Berthon P, Roller M, Zafrilla P, Issaly N, García-Conesa MT.

Molecules. 2015 Dec 11;20(12):22202-19. doi: 10.3390/molecules201219845.


Comprehensive characterization of the effects of ellagic acid and urolithins on colorectal cancer and key-associated molecular hallmarks: MicroRNA cell specific induction of CDKN1A (p21) as a common mechanism involved.

González-Sarrías A, Núñez-Sánchez MÁ, Tomé-Carneiro J, Tomás-Barberán FA, García-Conesa MT, Espín JC.

Mol Nutr Food Res. 2016 Apr;60(4):701-16. doi: 10.1002/mnfr.201500780. Epub 2015 Dec 29.


MicroRNAs expression in normal and malignant colon tissues as biomarkers of colorectal cancer and in response to pomegranate extracts consumption: Critical issues to discern between modulatory effects and potential artefacts.

Nuñez-Sánchez MA, Dávalos A, González-Sarrías A, Casas-Agustench P, Visioli F, Monedero-Saiz T, García-Talavera NV, Gómez-Sánchez MB, Sánchez-Álvarez C, García-Albert AM, Rodríguez-Gil FJ, Ruiz-Marín M, Pastor-Quirante FA, Martínez-Díaz F, Tomás-Barberán FA, García-Conesa MT, Espín JC.

Mol Nutr Food Res. 2015 Oct;59(10):1973-86. doi: 10.1002/mnfr.201500357. Epub 2015 Jul 20.


Dietary polyphenols against metabolic disorders: How far have we progressed in the understanding of the molecular mechanisms of action of these compounds?

García-Conesa MT.

Crit Rev Food Sci Nutr. 2017 Jun 13;57(9):1769-1786. doi: 10.1080/10408398.2014.980499. Review.


Dietary phenolics against colorectal cancer--From promising preclinical results to poor translation into clinical trials: Pitfalls and future needs.

Núñez-Sánchez MA, González-Sarrías A, Romo-Vaquero M, García-Villalba R, Selma MV, Tomás-Barberán FA, García-Conesa MT, Espín JC.

Mol Nutr Food Res. 2015 Jul;59(7):1274-91. doi: 10.1002/mnfr.201400866. Epub 2015 Mar 31. Review.


A rosemary extract rich in carnosic acid selectively modulates caecum microbiota and inhibits β-glucosidase activity, altering fiber and short chain fatty acids fecal excretion in lean and obese female rats.

Romo-Vaquero M, Selma MV, Larrosa M, Obiol M, García-Villalba R, González-Barrio R, Issaly N, Flanagan J, Roller M, Tomás-Barberán FA, García-Conesa MT.

PLoS One. 2014 Apr 14;9(4):e94687. doi: 10.1371/journal.pone.0094687. eCollection 2014.


A rosemary extract enriched in carnosic acid improves circulating adipocytokines and modulates key metabolic sensors in lean Zucker rats: Critical and contrasting differences in the obese genotype.

Romo-Vaquero M, Larrosa M, Yáñez-Gascón MJ, Issaly N, Flanagan J, Roller M, Tomás-Barberán FA, Espín JC, García-Conesa MT.

Mol Nutr Food Res. 2014 May;58(5):942-53. doi: 10.1002/mnfr.201300524. Epub 2013 Dec 23.


Phase-II metabolism limits the antiproliferative activity of urolithins in human colon cancer cells.

González-Sarrías A, Giménez-Bastida JA, Núñez-Sánchez MÁ, Larrosa M, García-Conesa MT, Tomás-Barberán FA, Espín JC.

Eur J Nutr. 2014 Apr;53(3):853-64.


Nutraceuticals for older people: facts, fictions and gaps in knowledge.

González-Sarrías A, Larrosa M, García-Conesa MT, Tomás-Barberán FA, Espín JC.

Maturitas. 2013 Aug;75(4):313-34. doi: 10.1016/j.maturitas.2013.05.006. Epub 2013 Jun 21. Review.


Biological significance of urolithins, the gut microbial ellagic Acid-derived metabolites: the evidence so far.

Espín JC, Larrosa M, García-Conesa MT, Tomás-Barberán F.

Evid Based Complement Alternat Med. 2013;2013:270418. doi: 10.1155/2013/270418. Epub 2013 May 28.


Bioavailability of the major bioactive diterpenoids in a rosemary extract: metabolic profile in the intestine, liver, plasma, and brain of Zucker rats.

Romo Vaquero M, García Villalba R, Larrosa M, Yáñez-Gascón MJ, Fromentin E, Flanagan J, Roller M, Tomás-Barberán FA, Espín JC, García-Conesa MT.

Mol Nutr Food Res. 2013 Oct;57(10):1834-46. doi: 10.1002/mnfr.201300052. Epub 2013 Apr 27.


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