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Items: 1 to 20 of 44

1.

Sphingolipids in Non-Alcoholic Fatty Liver Disease and Hepatocellular Carcinoma: Ceramide Turnover.

Simon J, Ouro A, Ala-Ibanibo L, Presa N, Delgado TC, Martínez-Chantar ML.

Int J Mol Sci. 2019 Dec 19;21(1). pii: E40. doi: 10.3390/ijms21010040. Review.

2.

Structural Insights into the Intracellular Region of the Human Magnesium Transport Mediator CNNM4.

Giménez-Mascarell P, Oyenarte I, González-Recio I, Fernández-Rodríguez C, Corral-Rodríguez MÁ, Campos-Zarraga I, Simón J, Kostantin E, Hardy S, Díaz Quintana A, Zubillaga Lizeaga M, Merino N, Diercks T, Blanco FJ, Díaz Moreno I, Martínez-Chantar ML, Tremblay ML, Müller D, Siliqi D, Martínez-Cruz LA.

Int J Mol Sci. 2019 Dec 12;20(24). pii: E6279. doi: 10.3390/ijms20246279.

3.

Ubiquitin-Like Post-Translational Modifications (Ubl-PTMs): Small Peptides with Huge Impact in Liver Fibrosis.

Lachiondo-Ortega S, Mercado-Gómez M, Serrano-Maciá M, Lopitz-Otsoa F, Salas-Villalobos TB, Varela-Rey M, Delgado TC, Martínez-Chantar ML.

Cells. 2019 Dec 4;8(12). pii: E1575. doi: 10.3390/cells8121575. Review.

4.

SerpinB3 Differently Up-Regulates Hypoxia Inducible Factors -1α and -2α in Hepatocellular Carcinoma: Mechanisms Revealing Novel Potential Therapeutic Targets.

Cannito S, Foglia B, Villano G, Turato C, Delgado TC, Morello E, Pin F, Novo E, Napione L, Quarta S, Ruvoletto M, Fasolato S, Zanus G, Colombatto S, Lopitz-Otsoa F, Fernández-Ramos D, Bussolino F, Sutti S, Albano E, Martínez-Chantar ML, Pontisso P, Parola M.

Cancers (Basel). 2019 Dec 4;11(12). pii: E1933. doi: 10.3390/cancers11121933.

5.

SUMO-Binding Entities (SUBEs) as Tools for the Enrichment, Isolation, Identification, and Characterization of the SUMO Proteome in Liver Cancer.

Lopitz-Otsoa F, Delgado TC, Lachiondo-Ortega S, Azkargorta M, Elortza F, Rodríguez MS, Martínez-Chantar ML.

J Vis Exp. 2019 Nov 1;(153). doi: 10.3791/60098.

PMID:
31736480
6.

Post-translational modifiers of liver kinase B1/serine/threonine kinase 11 in hepatocellular carcinoma.

Delgado TC, Lopitz-Otsoa F, Martínez-Chantar ML.

J Hepatocell Carcinoma. 2019 Jun 6;6:85-91. doi: 10.2147/JHC.S169585. eCollection 2019.

7.

Plasticity of adult hepatocytes and readjustment of cell fate: a novel dogma in liver disease.

Cubero FJ, Martinez-Chantar ML.

Gut. 2019 Jun;68(6):954-956. doi: 10.1136/gutjnl-2019-318218. Epub 2019 Mar 18. No abstract available.

PMID:
30885923
8.

Current Structural Knowledge on the CNNM Family of Magnesium Transport Mediators.

Giménez-Mascarell P, González-Recio I, Fernández-Rodríguez C, Oyenarte I, Müller D, Martínez-Chantar ML, Martínez-Cruz LA.

Int J Mol Sci. 2019 Mar 6;20(5). pii: E1135. doi: 10.3390/ijms20051135. Review.

9.

Atorvastatin provides a new lipidome improving early regeneration after partial hepatectomy in osteopontin deficient mice.

Nuñez-Garcia M, Gomez-Santos B, Saenz de Urturi D, Mestre D, Gonzalez-Romero F, Buque X, Gutiérrez-de Juan V, Martinez-Chantar ML, Syn WK, Fresnedo O, Aspichueta P.

Sci Rep. 2018 Oct 2;8(1):14626. doi: 10.1038/s41598-018-32919-9.

10.

Fine-Tuning of Sirtuin 1 Expression Is Essential to Protect the Liver From Cholestatic Liver Disease.

Blokker BA, Maijo M, Echeandia M, Galduroz M, Patterson AM, Ten A, Philo M, Schungel R, Gutierrez-de Juan V, Halilbasic E, Fuchs C, Le Gall G, Milkiewicz M, Milkiewicz P, Banales JM, Rushbrook SM, Mato JM, Trauner M, Müller M, Martínez-Chantar ML, Varela-Rey M, Beraza N.

Hepatology. 2019 Feb;69(2):699-716. doi: 10.1002/hep.30275.

11.

Neddylation, a novel paradigm in liver cancer.

Delgado TC, Barbier-Torres L, Zubiete-Franco I, Lopitz-Otsoa F, Varela-Rey M, Fernández-Ramos D, Martínez-Chantar ML.

Transl Gastroenterol Hepatol. 2018 Jun 30;3:37. doi: 10.21037/tgh.2018.06.05. eCollection 2018. Review.

12.

Liver Angiopoietin-2 Is a Key Predictor of De Novo or Recurrent Hepatocellular Cancer After Hepatitis C Virus Direct-Acting Antivirals.

Faillaci F, Marzi L, Critelli R, Milosa F, Schepis F, Turola E, Andreani S, Vandelli G, Bernabucci V, Lei B, D'Ambrosio F, Bristot L, Cavalletto L, Chemello L, Sighinolfi P, Manni P, Maiorana A, Caporali C, Bianchini M, Marsico M, Turco L, de Maria N, Del Buono M, Todesca P, di Lena L, Romagnoli D, Magistri P, di Benedetto F, Bruno S, Taliani G, Giannelli G, Martinez-Chantar ML, Villa E.

Hepatology. 2018 Sep;68(3):1010-1024. doi: 10.1002/hep.29911.

13.

The mitochondrial negative regulator MCJ is a therapeutic target for acetaminophen-induced liver injury.

Barbier-Torres L, Iruzubieta P, Fernández-Ramos D, Delgado TC, Taibo D, Guitiérrez-de-Juan V, Varela-Rey M, Azkargorta M, Navasa N, Fernández-Tussy P, Zubiete-Franco I, Simon J, Lopitz-Otsoa F, Lachiondo-Ortega S, Crespo J, Masson S, McCain MV, Villa E, Reeves H, Elortza F, Lucena MI, Hernández-Alvarez MI, Zorzano A, Andrade RJ, Lu SC, Mato JM, Anguita J, Rincón M, Martínez-Chantar ML.

Nat Commun. 2017 Dec 12;8(1):2068. doi: 10.1038/s41467-017-01970-x.

14.

Role of Aramchol in steatohepatitis and fibrosis in mice.

Iruarrizaga-Lejarreta M, Varela-Rey M, Fernández-Ramos D, Martínez-Arranz I, Delgado TC, Simon J, Juan VG, delaCruz-Villar L, Azkargorta M, Lavin JL, Mayo R, Van Liempd SM, Aurrekoetxea I, Buqué X, Cave DD, Peña A, Rodríguez-Cuesta J, Aransay AM, Elortza F, Falcón-Pérez JM, Aspichueta P, Hayardeny L, Noureddin M, Sanyal AJ, Alonso C, Anguita J, Martínez-Chantar ML, Lu SC, Mato JM.

Hepatol Commun. 2017 Nov;1(9):911-927. doi: 10.1002/hep4.1107. Epub 2017 Oct 4.

15.

The immunosuppressive effect of the tick protein, Salp15, is long-lasting and persists in a murine model of hematopoietic transplant.

Tomás-Cortázar J, Martín-Ruiz I, Barriales D, Pascual-Itoiz MÁ, de Juan VG, Caro-Maldonado A, Merino N, Marina A, Blanco FJ, Flores JM, Sutherland JD, Barrio R, Rojas A, Martínez-Chantar ML, Carracedo A, Simó C, García-Cañas V, Abecia L, Lavín JL, Aransay AM, Rodríguez H, Anguita J.

Sci Rep. 2017 Sep 6;7(1):10740. doi: 10.1038/s41598-017-11354-2.

16.

Microenvironment inflammatory infiltrate drives growth speed and outcome of hepatocellular carcinoma: a prospective clinical study.

Critelli R, Milosa F, Faillaci F, Condello R, Turola E, Marzi L, Lei B, Dituri F, Andreani S, Sighinolfi P, Manni P, Maiorana A, Caporali C, di Benedetto F, Del Buono M, De Maria N, Schepis F, Martinez-Chantar ML, Giannelli G, Villa E.

Cell Death Dis. 2017 Aug 24;8(8):e3017. doi: 10.1038/cddis.2017.395.

17.

Hypothalamic AMPK-ER Stress-JNK1 Axis Mediates the Central Actions of Thyroid Hormones on Energy Balance.

Martínez-Sánchez N, Seoane-Collazo P, Contreras C, Varela L, Villarroya J, Rial-Pensado E, Buqué X, Aurrekoetxea I, Delgado TC, Vázquez-Martínez R, González-García I, Roa J, Whittle AJ, Gomez-Santos B, Velagapudi V, Tung YCL, Morgan DA, Voshol PJ, Martínez de Morentin PB, López-González T, Liñares-Pose L, Gonzalez F, Chatterjee K, Sobrino T, Medina-Gómez G, Davis RJ, Casals N, Orešič M, Coll AP, Vidal-Puig A, Mittag J, Tena-Sempere M, Malagón MM, Diéguez C, Martínez-Chantar ML, Aspichueta P, Rahmouni K, Nogueiras R, Sabio G, Villarroya F, López M.

Cell Metab. 2017 Jul 5;26(1):212-229.e12. doi: 10.1016/j.cmet.2017.06.014.

18.

A morphological method for ammonia detection in liver.

Gutiérrez-de-Juan V, López de Davalillo S, Fernández-Ramos D, Barbier-Torres L, Zubiete-Franco I, Fernández-Tussy P, Simon J, Lopitz-Otsoa F, de Las Heras J, Iruzubieta P, Arias-Loste MT, Villa E, Crespo J, Andrade R, Lucena MI, Varela-Rey M, Lu SC, Mato JM, Delgado TC, Martínez-Chantar ML.

PLoS One. 2017 Mar 20;12(3):e0173914. doi: 10.1371/journal.pone.0173914. eCollection 2017.

19.

Metabolomic Identification of Subtypes of Nonalcoholic Steatohepatitis.

Alonso C, Fernández-Ramos D, Varela-Rey M, Martínez-Arranz I, Navasa N, Van Liempd SM, Lavín Trueba JL, Mayo R, Ilisso CP, de Juan VG, Iruarrizaga-Lejarreta M, delaCruz-Villar L, Mincholé I, Robinson A, Crespo J, Martín-Duce A, Romero-Gómez M, Sann H, Platon J, Van Eyk J, Aspichueta P, Noureddin M, Falcón-Pérez JM, Anguita J, Aransay AM, Martínez-Chantar ML, Lu SC, Mato JM.

Gastroenterology. 2017 May;152(6):1449-1461.e7. doi: 10.1053/j.gastro.2017.01.015. Epub 2017 Jan 26.

20.

Structural Basis of the Oncogenic Interaction of Phosphatase PRL-1 with the Magnesium Transporter CNNM2.

Giménez-Mascarell P, Oyenarte I, Hardy S, Breiderhoff T, Stuiver M, Kostantin E, Diercks T, Pey AL, Ereño-Orbea J, Martínez-Chantar ML, Khalaf-Nazzal R, Claverie-Martin F, Müller D, Tremblay ML, Martínez-Cruz LA.

J Biol Chem. 2017 Jan 20;292(3):786-801. doi: 10.1074/jbc.M116.759944. Epub 2016 Nov 29.

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