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Items: 1 to 20 of 30


HPLC-ESI- MS/MS analysis of beet (Beta vulgaris) leaves and its beneficial properties in type 1 diabetic rats.

Abd El-Ghffar EA, Hegazi NM, Saad HH, Soliman MM, El-Raey MA, Shehata SM, Barakat A, Yasri A, Sobeh M.

Biomed Pharmacother. 2019 Dec;120:109541. doi: 10.1016/j.biopha.2019.109541. Epub 2019 Oct 17.


Salix tetrasperma Roxb. Extract Alleviates Neuropathic Pain in Rats via Modulation of the NF-κB/TNF-α/NOX/iNOS Pathway.

Sobeh M, Mahmoud MF, Rezq S, Alsemeh AE, Sabry OM, Mostafa I, Abdelfattah MAO, El-Allem KA, El-Shazly AM, Yasri A, Wink M.

Antioxidants (Basel). 2019 Oct 12;8(10). pii: E482. doi: 10.3390/antiox8100482.


Chemical Profiling of Polyphenolics in Eucalyptus globulus and Evaluation of Its Hepato-Renal Protective Potential Against Cyclophosphamide Induced Toxicity in Mice.

Ghareeb MA, Sobeh M, El-Maadawy WH, Mohammed HS, Khalil H, Botros S, Wink M.

Antioxidants (Basel). 2019 Sep 19;8(9). pii: E415. doi: 10.3390/antiox8090415.


Chrysophanol, Physcion, Hesperidin and Curcumin Modulate the Gene Expression of Pro-Inflammatory Mediators Induced by LPS in HepG2: In Silico and Molecular Studies.

Selim NM, Elgazar AA, Abdel-Hamid NM, El-Magd MRA, Yasri A, Hefnawy HME, Sobeh M.

Antioxidants (Basel). 2019 Sep 3;8(9). pii: E371. doi: 10.3390/antiox8090371.


Characterization of phenolic compounds from Eugenia supra-axillaris leaf extract using HPLC-PDA-MS/MS and its antioxidant, anti-inflammatory, antipyretic and pain killing activities in vivo.

Hegazi NM, Sobeh M, Rezq S, El-Raey MA, Dmirieh M, El-Shazly AM, Mahmoud MF, Wink M.

Sci Rep. 2019 Jul 31;9(1):11122. doi: 10.1038/s41598-019-46946-7.


Phenolic Compounds from Populus alba L. and Salix subserrata Willd. (Salicaceae) Counteract Oxidative Stress in Caenorhabditis elegans.

Tawfeek N, Sobeh M, Hamdan DI, Farrag N, Roxo M, El-Shazly AM, Wink M.

Molecules. 2019 May 24;24(10). pii: E1999. doi: 10.3390/molecules24101999.


Chemical profiling of secondary metabolites of Eugenia uniflora and their antioxidant, anti-inflammatory, pain killing and anti-diabetic activities: A comprehensive approach.

Sobeh M, El-Raey M, Rezq S, Abdelfattah MAO, Petruk G, Osman S, El-Shazly AM, El-Beshbishy HA, Mahmoud MF, Wink M.

J Ethnopharmacol. 2019 Aug 10;240:111939. doi: 10.1016/j.jep.2019.111939. Epub 2019 May 13.


Albizia anthelmintica: HPLC-MS/MS profiling and in vivo anti-inflammatory, pain killing and antipyretic activities of its leaf extract.

Sobeh M, Rezq S, Sabry OM, Abdelfattah MAO, El Raey MA, El-Kashak WA, El-Shazly AM, Mahmoud MF, Wink M.

Biomed Pharmacother. 2019 Jul;115:108882. doi: 10.1016/j.biopha.2019.108882. Epub 2019 Apr 24.


Chemical composition, antioxidant and hepatoprotective activities of methanol extracts from leaves of Terminalia bellirica and Terminalia sericea (Combretaceae).

Sobeh M, Mahmoud MF, Hasan RA, Abdelfattah MAO, Osman S, Rashid HO, El-Shazly AM, Wink M.

PeerJ. 2019 Feb 27;7:e6322. doi: 10.7717/peerj.6322. eCollection 2019.


A New Polyoxygenated Flavonol Gossypetin-3-O-β-d-Robinobioside from Caesalpinia gilliesii (Hook.) D. Dietr. and In Vivo Hepatoprotective, Anti-Inflammatory, and Anti-Ulcer Activities of the Leaf Methanol Extract.

Emam M, El Raey MA, El-Haddad AE, El Awdan SA, Rabie AM, El-Ansari MA, Sobeh M, Osman SM, Wink M.

Molecules. 2018 Dec 31;24(1). pii: E138. doi: 10.3390/molecules24010138.


HPLC-ESI-MS/MS Profiling of Polyphenolics of a Leaf Extract from Alpinia zerumbet (Zingiberaceae) and Its Anti-Inflammatory, Anti-Nociceptive, and Antipyretic Activities In Vivo.

Ghareeb MA, Sobeh M, Rezq S, El-Shazly AM, Mahmoud MF, Wink M.

Molecules. 2018 Dec 7;23(12). pii: E3238. doi: 10.3390/molecules23123238.


Syzygium aqueum: A Polyphenol- Rich Leaf Extract Exhibits Antioxidant, Hepatoprotective, Pain-Killing and Anti-inflammatory Activities in Animal Models.

Sobeh M, Mahmoud MF, Petruk G, Rezq S, Ashour ML, Youssef FS, El-Shazly AM, Monti DM, Abdel-Naim AB, Wink M.

Front Pharmacol. 2018 Jun 5;9:566. doi: 10.3389/fphar.2018.00566. eCollection 2018.


Tannin-rich extracts from Lannea stuhlmannii and Lannea humilis (Anacardiaceae) exhibit hepatoprotective activities in vivo via enhancement of the anti-apoptotic protein Bcl-2.

Sobeh M, Mahmoud MF, Hasan RA, Abdelfattah MAO, Sabry OM, Ghareeb MA, El-Shazly AM, Wink M.

Sci Rep. 2018 Jun 19;8(1):9343. doi: 10.1038/s41598-018-27452-8.


Anti-Parasitic Activities of Allium sativum and Allium cepa against Trypanosoma b. brucei and Leishmania tarentolae.

Krstin S, Sobeh M, Braun MS, Wink M.

Medicines (Basel). 2018 Apr 21;5(2). pii: E37. doi: 10.3390/medicines5020037.


Evidence for the anti-inflammatory activity of Bupleurum marginatum (Apiaceae) extracts using in vitro and in vivo experiments supported by virtual screening.

Ashour ML, Youssef FS, Gad HA, El-Readi MZ, Bouzabata A, Abuzeid RM, Sobeh M, Wink M.

J Pharm Pharmacol. 2018 Jul;70(7):952-963. doi: 10.1111/jphp.12904. Epub 2018 Apr 3.


Rheum palmatum root extract inhibits hepatocellular carcinoma in rats treated with diethylnitrosamine.

El-Saied MA, Sobeh M, Abdo W, Badr OM, Youssif LT, Elsayed IH, Osman SM, Wink M.

J Pharm Pharmacol. 2018 Jun;70(6):821-829. doi: 10.1111/jphp.12899. Epub 2018 Mar 9.


Tulbaghia violacea and Allium ursinum Extracts Exhibit Anti-Parasitic and Antimicrobial Activities.

Krstin S, Sobeh M, Braun MS, Wink M.

Molecules. 2018 Feb 2;23(2). pii: E313. doi: 10.3390/molecules23020313.


High resolution UPLC-MS/MS profiling of polyphenolics in the methanol extract of Syzygium samarangense leaves and its hepatoprotective activity in rats with CCl4-induced hepatic damage.

Sobeh M, Youssef FS, Esmat A, Petruk G, El-Khatib AH, Monti DM, Ashour ML, Wink M.

Food Chem Toxicol. 2018 Mar;113:145-153. doi: 10.1016/j.fct.2018.01.031. Epub 2018 Jan 31.


HPLC-PDA-MS/MS Characterization of Bioactive Secondary Metabolites from Turraea fischeri Bark Extract and Its Antioxidant and Hepatoprotective Activities In Vivo.

Sobeh M, Mahmoud MF, Sabry OM, Adel R, Dmirieh M, El-Shazly AM, Wink M.

Molecules. 2017 Nov 29;22(12). pii: E2089. doi: 10.3390/molecules22122089.

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