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Items: 1 to 20 of 54


Pharmacological cholesterol depletion disturbs ciliogenesis and ciliary function in developing zebrafish.

Maerz LD, Burkhalter MD, Schilpp C, Wittekindt OH, Frick M, Philipp M.

Commun Biol. 2019 Jan 29;2(1):31. doi: 10.1038/s42003-018-0272-7.


Retinoic acid signalling adjusts tight junction permeability in response to air-liquid interface conditions.

Lochbaum R, Schilpp C, Nonnenmacher L, Frick M, Dietl P, Wittekindt OH.

Cell Signal. 2020 Jan;65:109421. doi: 10.1016/j.cellsig.2019.109421. Epub 2019 Sep 16.


Measuring the Action of Oligonucleotide Therapeutics in the Lung at the Cell Type-Specific Level by Tissue Disruption and Cell Sorting (TDCS).

Graves H, Evans S, Fauler M, Frick M, Moschos SA.

Methods Mol Biol. 2019;2036:187-203. doi: 10.1007/978-1-4939-9670-4_11.


Supramolecular Toxin Complexes for Targeted Pharmacological Modulation of Polymorphonuclear Leukocyte Functions.

Heck AJ, Ostertag T, Schnell L, Fischer S, Agrawalla BK, Winterwerber P, Wirsching E, Fauler M, Frick M, Kuan SL, Weil T, Barth H.

Adv Healthc Mater. 2019 Sep;8(17):e1900665. doi: 10.1002/adhm.201900665. Epub 2019 Jul 18.


IL-13 Impairs Tight Junctions in Airway Epithelia.

Schmidt H, Braubach P, Schilpp C, Lochbaum R, Neuland K, Thompson K, Jonigk D, Frick M, Dietl P, Wittekindt OH.

Int J Mol Sci. 2019 Jun 30;20(13). pii: E3222. doi: 10.3390/ijms20133222.


Sensory contact to the stressor prevents recovery from structural and functional heart damage following psychosocial trauma.

Foertsch S, Lackner I, Weber B, Füchsl AM, Langgartner D, Wirkert E, Peters S, Fois G, Pressmar J, Fegert JM, Frick M, Gündel H, Kalbitz M, Reber SO.

Brain Behav Immun. 2019 Aug;80:667-677. doi: 10.1016/j.bbi.2019.05.013. Epub 2019 May 11.


Human lung fibroblast-to-myofibroblast transformation is not driven by an LDH5-dependent metabolic shift towards aerobic glycolysis.

Schruf E, Schroeder V, Kuttruff CA, Weigle S, Krell M, Benz M, Bretschneider T, Holweg A, Schuler M, Frick M, Nicklin P, Garnett JP, Sobotta MC.

Respir Res. 2019 May 9;20(1):87. doi: 10.1186/s12931-019-1058-2.


P2X4 and lysosome fusion.

Murrell-Lagnado RD, Frick M.

Curr Opin Pharmacol. 2019 Aug;47:126-132. doi: 10.1016/j.coph.2019.03.002. Epub 2019 Apr 28. Review.


Pharmacological cholesterol depletion disturbs ciliogenesis and ciliary function in developing zebrafish.

Maerz LD, Burkhalter MD, Schilpp C, Wittekindt OH, Frick M, Philipp M.

Commun Biol. 2019 Jan 29;2:31. doi: 10.1038/s42003-018-0272-7. eCollection 2019.


Revisiting an old antibiotic: bacitracin neutralizes binary bacterial toxins and protects cells from intoxication.

Schnell L, Felix I, Müller B, Sadi M, von Bank F, Papatheodorou P, Popoff MR, Aktories K, Waltenberger E, Benz R, Weichbrodt C, Fauler M, Frick M, Barth H.

FASEB J. 2019 Apr;33(4):5755-5771. doi: 10.1096/fj.201802453R. Epub 2019 Jan 30.


Inflammation-induced upregulation of P2X4 expression augments mucin secretion in airway epithelia.

Winkelmann VE, Thompson KE, Neuland K, Jaramillo AM, Fois G, Schmidt H, Wittekindt OH, Han W, Tuvim MJ, Dickey BF, Dietl P, Frick M.

Am J Physiol Lung Cell Mol Physiol. 2019 Jan 1;316(1):L58-L70. doi: 10.1152/ajplung.00157.2018. Epub 2018 Oct 25.


Medium throughput breathing human primary cell alveolus-on-chip model.

Stucki JD, Hobi N, Galimov A, Stucki AO, Schneider-Daum N, Lehr CM, Huwer H, Frick M, Funke-Chambour M, Geiser T, Guenat OT.

Sci Rep. 2018 Sep 25;8(1):14359. doi: 10.1038/s41598-018-32523-x.


P2X4 receptor re-sensitization depends on a protonation/deprotonation cycle mediated by receptor internalization and recycling.

Fois G, Föhr KJ, Kling C, Fauler M, Wittekindt OH, Dietl P, Frick M.

J Physiol. 2018 Oct;596(20):4893-4907. doi: 10.1113/JP275448. Epub 2018 Sep 17.


Complement C5a Alters the Membrane Potential of Neutrophils during Hemorrhagic Shock.

Messerer DAC, Denk S, Föhr KJ, Halbgebauer R, Braun CK, Hönes F, Harant J, Fauler M, Frick M, Nußbaum BL, Radermacher P, Hafner S, Huber-Lang MS.

Mediators Inflamm. 2018 May 29;2018:2052356. doi: 10.1155/2018/2052356. eCollection 2018.


Pulmonary surfactant protein SP-B promotes exocytosis of lamellar bodies in alveolar type II cells.

Martínez-Calle M, Olmeda B, Dietl P, Frick M, Pérez-Gil J.

FASEB J. 2018 Aug;32(8):4600-4611. doi: 10.1096/fj.201701462RR. Epub 2018 Mar 15.


ATP is stored in lamellar bodies to activate vesicular P2X4 in an autocrine fashion upon exocytosis.

Fois G, Winkelmann VE, Bareis L, Staudenmaier L, Hecht E, Ziller C, Ehinger K, Schymeinsky J, Kranz C, Frick M.

J Gen Physiol. 2018 Feb 5;150(2):277-291. doi: 10.1085/jgp.201711870. Epub 2017 Dec 27.


A Tyrosine-Based Trafficking Motif of the Tegument Protein pUL71 Is Crucial for Human Cytomegalovirus Secondary Envelopment.

Dietz AN, Villinger C, Becker S, Frick M, von Einem J.

J Virol. 2017 Dec 14;92(1). pii: e00907-17. doi: 10.1128/JVI.00907-17. Print 2018 Jan 1.


Hsp70 facilitates trans-membrane transport of bacterial ADP-ribosylating toxins into the cytosol of mammalian cells.

Ernst K, Schmid J, Beck M, Hägele M, Hohwieler M, Hauff P, Ückert AK, Anastasia A, Fauler M, Jank T, Aktories K, Popoff MR, Schiene-Fischer C, Kleger A, Müller M, Frick M, Barth H.

Sci Rep. 2017 Jun 2;7(1):2724. doi: 10.1038/s41598-017-02882-y.


The Hsp90 machinery facilitates the transport of diphtheria toxin into human cells.

Schuster M, Schnell L, Feigl P, Birkhofer C, Mohr K, Roeder M, Carle S, Langer S, Tippel F, Buchner J, Fischer G, Hausch F, Frick M, Schwan C, Aktories K, Schiene-Fischer C, Barth H.

Sci Rep. 2017 Apr 4;7(1):613. doi: 10.1038/s41598-017-00780-x.


Performance Testing of RREB1, MYB, and CCND1 Fluorescence In Situ Hybridization in Spindle-Cell and Desmoplastic Melanoma Argues for a Two-Step Test Algorithm.

Weissinger SE, Frick M, Möller P, Horst BA, Lennerz JK.

Int J Surg Pathol. 2017 Apr;25(2):148-157. doi: 10.1177/1066896916680072. Epub 2016 Nov 30.


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