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Items: 1 to 20 of 148

1.

An apically located hybrid guanylate cyclase-ATPase is critical for the initiation of Ca2+ signaling and motility in Toxoplasma gondii.

Yang L, Uboldi AD, Seizova S, Wilde ML, Coffey MJ, Katris NJ, Yamaryo-Botté Y, Kocan M, Bathgate RAD, Stewart RJ, McConville MJ, Thompson PE, Botté CY, Tonkin CJ.

J Biol Chem. 2019 May 31;294(22):8959-8972. doi: 10.1074/jbc.RA118.005491. Epub 2019 Apr 16.

PMID:
30992368
2.

Mus musculus deficient for secretory antibodies show delayed growth with an altered urinary metabolome.

Simpfendorfer KR, Wang N, Tull DL, De Souza DP, Nahid A, Mu A, Hocking DM, Pedersen JS, Wijburg OLC, McConville MJ, Strugnell RA.

Mol Med. 2019 Apr 3;25(1):12. doi: 10.1186/s10020-019-0077-2.

3.

Circadian and wake-dependent changes in human plasma polar metabolites during prolonged wakefulness: A preliminary analysis.

Grant LK, Ftouni S, Nijagal B, De Souza DP, Tull D, McConville MJ, Rajaratnam SMW, Lockley SW, Anderson C.

Sci Rep. 2019 Mar 14;9(1):4428. doi: 10.1038/s41598-019-40353-8.

4.

Antibiotic resistance and host immune evasion in Staphylococcus aureus mediated by a metabolic adaptation.

Jiang JH, Bhuiyan MS, Shen HH, Cameron DR, Rupasinghe TWT, Wu CM, Le Brun AP, Kostoulias X, Domene C, Fulcher AJ, McConville MJ, Howden BP, Lieschke GJ, Peleg AY.

Proc Natl Acad Sci U S A. 2019 Feb 26;116(9):3722-3727. doi: 10.1073/pnas.1812066116. Epub 2019 Feb 11.

PMID:
30808758
5.

The tyrosine transporter of Toxoplasma gondii is a member of the newly defined apicomplexan amino acid transporter (ApiAT) family.

Parker KER, Fairweather SJ, Rajendran E, Blume M, McConville MJ, Bröer S, Kirk K, van Dooren GG.

PLoS Pathog. 2019 Feb 11;15(2):e1007577. doi: 10.1371/journal.ppat.1007577. eCollection 2019 Feb.

6.

Hookworm-Derived Metabolites Suppress Pathology in a Mouse Model of Colitis and Inhibit Secretion of Key Inflammatory Cytokines in Primary Human Leukocytes.

Wangchuk P, Shepherd C, Constantinoiu C, Ryan RYM, Kouremenos KA, Becker L, Jones L, Buitrago G, Giacomin P, Wilson D, Daly N, McConville MJ, Miles JJ, Loukas A.

Infect Immun. 2019 Mar 25;87(4). pii: e00851-18. doi: 10.1128/IAI.00851-18. Print 2019 Apr.

PMID:
30670556
7.

Determining the Mode of Action of Antimalarial Drugs Using Time-Resolved LC-MS-Based Metabolite Profiling.

Cobbold SA, McConville MJ.

Methods Mol Biol. 2019;1859:225-239. doi: 10.1007/978-1-4939-8757-3_12.

PMID:
30421232
8.

NLRP1 restricts butyrate producing commensals to exacerbate inflammatory bowel disease.

Tye H, Yu CH, Simms LA, de Zoete MR, Kim ML, Zakrzewski M, Penington JS, Harapas CR, Souza-Fonseca-Guimaraes F, Wockner LF, Preaudet A, Mielke LA, Wilcox SA, Ogura Y, Corr SC, Kanojia K, Kouremenos KA, De Souza DP, McConville MJ, Flavell RA, Gerlic M, Kile BT, Papenfuss AT, Putoczki TL, Radford-Smith GL, Masters SL.

Nat Commun. 2018 Sep 13;9(1):3728. doi: 10.1038/s41467-018-06125-0.

9.

Protein kinase A negatively regulates Ca2+ signalling in Toxoplasma gondii.

Uboldi AD, Wilde ML, McRae EA, Stewart RJ, Dagley LF, Yang L, Katris NJ, Hapuarachchi SV, Coffey MJ, Lehane AM, Botte CY, Waller RF, Webb AI, McConville MJ, Tonkin CJ.

PLoS Biol. 2018 Sep 12;16(9):e2005642. doi: 10.1371/journal.pbio.2005642. eCollection 2018 Sep.

10.

Large-scale plasma lipidomic profiling identifies lipids that predict cardiovascular events in secondary prevention.

Mundra PA, Barlow CK, Nestel PJ, Barnes EH, Kirby A, Thompson P, Sullivan DR, Alshehry ZH, Mellett NA, Huynh K, Jayawardana KS, Giles C, McConville MJ, Zoungas S, Hillis GS, Chalmers J, Woodward M, Wong G, Kingwell BA, Simes J, Tonkin AM, Meikle PJ; LIPID Study Investigators.

JCI Insight. 2018 Sep 6;3(17). pii: 121326. doi: 10.1172/jci.insight.121326. eCollection 2018 Sep 6.

11.

Identification of novel lipid modifications and intermembrane dynamics in Corynebacterium glutamicum using high-resolution mass spectrometry.

Klatt S, Brammananth R, O'Callaghan S, Kouremenos KA, Tull D, Crellin PK, Coppel RL, McConville MJ.

J Lipid Res. 2018 Jul;59(7):1190-1204. doi: 10.1194/jlr.M082784. Epub 2018 May 3.

PMID:
29724782
12.

Methionine biosynthesis and transport are functionally redundant for the growth and virulence of Salmonella Typhimurium.

Husna AU, Wang N, Cobbold SA, Newton HJ, Hocking DM, Wilksch JJ, Scott TA, Davies MR, Hinton JC, Tree JJ, Lithgow T, McConville MJ, Strugnell RA.

J Biol Chem. 2018 Jun 15;293(24):9506-9519. doi: 10.1074/jbc.RA118.002592. Epub 2018 May 2.

13.

Phospholipase A2 activity during the replication cycle of the flavivirus West Nile virus.

Liebscher S, Ambrose RL, Aktepe TE, Mikulasova A, Prier JE, Gillespie LK, Lopez-Denman AJ, Rupasinghe TWT, Tull D, McConville MJ, Mackenzie JM.

PLoS Pathog. 2018 Apr 30;14(4):e1007029. doi: 10.1371/journal.ppat.1007029. eCollection 2018 Apr.

14.

Talaromyces marneffei simA Encodes a Fungal Cytochrome P450 Essential for Survival in Macrophages.

Boyce KJ, De Souza DP, Dayalan S, Pasricha S, Tull D, McConville MJ, Andrianopoulos A.

mSphere. 2018 Mar 21;3(2). pii: e00056-18. doi: 10.1128/mSphere.00056-18. eCollection 2018 Mar-Apr.

15.

The Plasmodium falciparum transcriptome in severe malaria reveals altered expression of genes involved in important processes including surface antigen-encoding var genes.

Tonkin-Hill GQ, Trianty L, Noviyanti R, Nguyen HHT, Sebayang BF, Lampah DA, Marfurt J, Cobbold SA, Rambhatla JS, McConville MJ, Rogerson SJ, Brown GV, Day KP, Price RN, Anstey NM, Papenfuss AT, Duffy MF.

PLoS Biol. 2018 Mar 12;16(3):e2004328. doi: 10.1371/journal.pbio.2004328. eCollection 2018 Mar.

16.

Synergy between the KEAP1/NRF2 and PI3K Pathways Drives Non-Small-Cell Lung Cancer with an Altered Immune Microenvironment.

Best SA, De Souza DP, Kersbergen A, Policheni AN, Dayalan S, Tull D, Rathi V, Gray DH, Ritchie ME, McConville MJ, Sutherland KD.

Cell Metab. 2018 Apr 3;27(4):935-943.e4. doi: 10.1016/j.cmet.2018.02.006. Epub 2018 Mar 8.

17.

Leishmania mexicana can utilize amino acids as major carbon sources in macrophages but not in animal models.

Saunders EC, Naderer T, Chambers J, Landfear SM, McConville MJ.

Mol Microbiol. 2018 Apr;108(2):143-158. doi: 10.1111/mmi.13923. Epub 2018 Mar 2.

PMID:
29411460
18.

DExSI: a new tool for the rapid quantitation of 13C-labelled metabolites detected by GC-MS.

Dagley MJ, McConville MJ.

Bioinformatics. 2018 Jun 1;34(11):1957-1958. doi: 10.1093/bioinformatics/bty025.

19.

Extensive Metabolic Remodeling Differentiates Non-pathogenic and Pathogenic Growth Forms of the Dimorphic Pathogen Talaromyces marneffei.

Pasricha S, MacRae JI, Chua HH, Chambers J, Boyce KJ, McConville MJ, Andrianopoulos A.

Front Cell Infect Microbiol. 2017 Aug 17;7:368. doi: 10.3389/fcimb.2017.00368. eCollection 2017.

20.

Sengers Syndrome-Associated Mitochondrial Acylglycerol Kinase Is a Subunit of the Human TIM22 Protein Import Complex.

Kang Y, Stroud DA, Baker MJ, De Souza DP, Frazier AE, Liem M, Tull D, Mathivanan S, McConville MJ, Thorburn DR, Ryan MT, Stojanovski D.

Mol Cell. 2017 Aug 3;67(3):457-470.e5. doi: 10.1016/j.molcel.2017.06.014. Epub 2017 Jul 14.

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