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Items: 10


Early alterations in stem-like/resident T cells, innate and myeloid cells in the bone marrow in preneoplastic gammopathy.

Bailur JK, McCachren SS, Doxie DB, Shrestha M, Pendleton K, Nooka AK, Neparidze N, Parker TL, Bar N, Kaufman JL, Hofmeister CC, Boise LH, Lonial S, Kemp ML, Dhodapkar KM, Dhodapkar MV.

JCI Insight. 2019 Apr 23;5. pii: 127807. doi: 10.1172/jci.insight.127807.


A FOXO1-induced oncogenic network defines the AML1-ETO preleukemic program.

Lin S, Ptasinska A, Chen X, Shrestha M, Assi SA, Chin PS, Imperato MR, Aronow BJ, Zhang J, Weirauch MT, Bonifer C, Mulloy JC.

Blood. 2017 Sep 7;130(10):1213-1222. doi: 10.1182/blood-2016-11-750976. Epub 2017 Jul 14.


The full transforming capacity of MLL-Af4 is interlinked with lymphoid lineage commitment.

Lin S, Luo RT, Shrestha M, Thirman MJ, Mulloy JC.

Blood. 2017 Aug 17;130(7):903-907. doi: 10.1182/blood-2017-04-777185. Epub 2017 Jun 21.


Supraphysiologic levels of the AML1-ETO isoform AE9a are essential for transformation.

Link KA, Lin S, Shrestha M, Bowman M, Wunderlich M, Bloomfield CD, Huang G, Mulloy JC.

Proc Natl Acad Sci U S A. 2016 Aug 9;113(32):9075-80. doi: 10.1073/pnas.1524225113. Epub 2016 Jul 25.


How can we better serve adolescent key populations? Strategies to encourage and inform future data collection, analysis, and use.

Dayton R, Nary P, Cunningham J, Plourde KF, Green K, Wambugu S, Shrestha M, Aiyenigba B, Ngige E.

Glob Public Health. 2017 Aug;12(8):941-953. doi: 10.1080/17441692.2016.1170177. Epub 2016 Apr 24.


Acute pancreatitis with normal amylase and lipase--an ED dilemma.

Singh A, Shrestha M, Anand C.

Am J Emerg Med. 2016 May;34(5):940.e5-7. doi: 10.1016/j.ajem.2015.10.026. Epub 2015 Oct 23. No abstract available.


MAPK8-mediated stabilization of SP1 is essential for RUNX1-RUNX1T1 - driven leukaemia.

Maiques-Diaz A, Hernando M, Sánchez-López A, Rio-Machin A, Shrestha M, Mulloy JC, Cigudosa JC, Alvarez S.

Br J Haematol. 2016 Mar;172(5):807-10. doi: 10.1111/bjh.13536. Epub 2015 Jun 8. No abstract available.


AML cells are differentially sensitive to chemotherapy treatment in a human xenograft model.

Wunderlich M, Mizukawa B, Chou FS, Sexton C, Shrestha M, Saunthararajah Y, Mulloy JC.

Blood. 2013 Mar 21;121(12):e90-7. doi: 10.1182/blood-2012-10-464677. Epub 2013 Jan 24.


The thrombopoietin/MPL/Bcl-xL pathway is essential for survival and self-renewal in human preleukemia induced by AML1-ETO.

Chou FS, Griesinger A, Wunderlich M, Lin S, Link KA, Shrestha M, Goyama S, Mizukawa B, Shen S, Marcucci G, Mulloy JC.

Blood. 2012 Jul 26;120(4):709-19. doi: 10.1182/blood-2012-01-403212. Epub 2012 Feb 14.


Inhibition of Rac GTPase signaling and downstream prosurvival Bcl-2 proteins as combination targeted therapy in MLL-AF9 leukemia.

Mizukawa B, Wei J, Shrestha M, Wunderlich M, Chou FS, Griesinger A, Harris CE, Kumar AR, Zheng Y, Williams DA, Mulloy JC.

Blood. 2011 Nov 10;118(19):5235-45. doi: 10.1182/blood-2011-04-351817. Epub 2011 Sep 22.

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