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Items: 1 to 20 of 46

1.

Evaluation of NV556, a Novel Cyclophilin Inhibitor, as a Potential Antifibrotic Compound for Liver Fibrosis.

Simón Serrano S, Grönberg A, Longato L, Rombouts K, Kuo J, Gregory M, Moss S, Elmér E, Mazza G, Gallay P, Pinzani M, Hansson MJ, Massoumi R.

Cells. 2019 Nov 8;8(11). pii: E1409. doi: 10.3390/cells8111409.

2.

Copenhagen Head Injury Ciclosporin Study: A Phase IIa Safety, Pharmacokinetics, and Biomarker Study of Ciclosporin in Severe Traumatic Brain Injury Patients.

Kelsen J, Karlsson M, Hansson MJ, Yang Z, Fischer W, Hugerth M, Nordström CH, Åstrand R, Keep MF, Kilbaugh T, Wang KKW, Møller K, Juhler M, Elmér E.

J Neurotrauma. 2019 Dec 1;36(23):3253-3263. doi: 10.1089/neu.2018.6369. Epub 2019 Aug 1.

3.

Bioenergetic bypass using cell-permeable succinate, but not methylene blue, attenuates metformin-induced lactate production.

Piel S, Ehinger JK, Chamkha I, Frostner EÅ, Sjövall F, Elmér E, Hansson MJ.

Intensive Care Med Exp. 2018 Aug 1;6(1):22. doi: 10.1186/s40635-018-0186-1.

4.

Neuroprotective Effects of Cyclosporine in a Porcine Pre-Clinical Trial of Focal Traumatic Brain Injury.

Karlsson M, Pukenas B, Chawla S, Ehinger JK, Plyler R, Stolow M, Gabello M, Hugerth M, Elmér E, Hansson MJ, Margulies S, Kilbaugh T.

J Neurotrauma. 2018 Jul 24. doi: 10.1089/neu.2018.5706. [Epub ahead of print]

5.

Effect and Safety of Morphine Use in Acute Anterior ST-Segment Elevation Myocardial Infarction.

Bonin M, Mewton N, Roubille F, Morel O, Cayla G, Angoulvant D, Elbaz M, Claeys MJ, Garcia-Dorado D, Giraud C, Rioufol G, Jossan C, Ovize M, Guerin P; CIRCUS Study Investigators.

J Am Heart Assoc. 2018 Feb 10;7(4). pii: e006833. doi: 10.1161/JAHA.117.006833.

6.

Cyclosporine before Coronary Artery Bypass Grafting Does Not Prevent Postoperative Decreases in Renal Function: A Randomized Clinical Trial.

Ederoth P, Dardashti A, Grins E, Brondén B, Metzsch C, Erdling A, Nozohoor S, Mokhtari A, Hansson MJ, Elmér E, Algotsson L, Jovinge S, Bjursten H.

Anesthesiology. 2018 Apr;128(4):710-717. doi: 10.1097/ALN.0000000000002104. Erratum in: Anesthesiology. 2019 Feb;130(2):360.

PMID:
29369890
7.

Oxygen consumption in platelets as an adjunct diagnostic method for pediatric mitochondrial disease.

Westerlund E, Marelsson SE, Ehinger JK, Sjövall F, Morota S, Åsander Frostner E, Oldfors A, Darin N, Lundgren J, Hansson MJ, Fellman V, Elmér E.

Pediatr Res. 2018 Feb;83(2):455-465. doi: 10.1038/pr.2017.250. Epub 2017 Nov 15.

PMID:
28981487
8.

Ciclosporin to Protect Renal function In Cardiac Surgery (CiPRICS): a study protocol for a double-blind, randomised, placebo-controlled, proof-of-concept study.

Ederoth P, Grins E, Dardashti A, Brondén B, Metzsch C, Erdling A, Nozohoor S, Mokhtari A, Hansson MJ, Elmér E, Algotsson L, Jovinge S, Bjursten H.

BMJ Open. 2016 Dec 15;6(12):e012299. doi: 10.1136/bmjopen-2016-012299.

9.

Changes in energy metabolism due to acute rotenone-induced mitochondrial complex I dysfunction - An in vivo large animal model.

Karlsson M, Ehinger JK, Piel S, Sjövall F, Henriksnäs J, Höglund U, Hansson MJ, Elmér E.

Mitochondrion. 2016 Nov;31:56-62. doi: 10.1016/j.mito.2016.10.003. Epub 2016 Oct 18.

PMID:
27769952
10.

The radiation dose to overweighted patients undergoing myocardial perfusion SPECT can be significantly reduced: validation of a linear weight-adjusted activity administration protocol.

Oddstig J, Hindorf C, Hedeer F, Jögi J, Arheden H, Hansson MJ, Engblom H.

J Nucl Cardiol. 2017 Dec;24(6):1912-1921. doi: 10.1007/s12350-016-0628-7. Epub 2016 Aug 9.

PMID:
27506700
11.

Cell-permeable succinate prodrugs bypass mitochondrial complex I deficiency.

Ehinger JK, Piel S, Ford R, Karlsson M, Sjövall F, Frostner EÅ, Morota S, Taylor RW, Turnbull DM, Cornell C, Moss SJ, Metzsch C, Hansson MJ, Fliri H, Elmér E.

Nat Commun. 2016 Aug 9;7:12317. doi: 10.1038/ncomms12317.

12.

Mitochondrial Respiratory Function in Peripheral Blood Cells from Huntington's Disease Patients.

Ehinger JK, Morota S, Hansson MJ, Paul G, Elmér E.

Mov Disord Clin Pract. 2016 Feb 11;3(5):472-482. doi: 10.1002/mdc3.12308. eCollection 2016 Sep-Oct.

13.

Mitochondrial response in a toddler-aged swine model following diffuse non-impact traumatic brain injury.

Kilbaugh TJ, Karlsson M, Duhaime AC, Hansson MJ, Elmer E, Margulies SS.

Mitochondrion. 2016 Jan;26:19-25. doi: 10.1016/j.mito.2015.11.001. Epub 2015 Nov 5.

14.

DIVERSE AND TISSUE-SPECIFIC MITOCHONDRIAL RESPIRATORY RESPONSE IN A MOUSE MODEL OF SEPSIS-INDUCED MULTIPLE ORGAN FAILURE.

Karlsson M, Hara N, Morata S, Sjövall F, Kilbaugh T, Hansson MJ, Uchino H, Elmér E.

Shock. 2016 Apr;45(4):404-10. doi: 10.1097/SHK.0000000000000525.

PMID:
26536202
15.

Persistently Altered Brain Mitochondrial Bioenergetics After Apparently Successful Resuscitation From Cardiac Arrest.

Kilbaugh TJ, Sutton RM, Karlsson M, Hansson MJ, Naim MY, Morgan RW, Bratinov G, Lampe JW, Nadkarni VM, Becker LB, Margulies SS, Berg RA.

J Am Heart Assoc. 2015 Sep 14;4(9):e002232. doi: 10.1161/JAHA.115.002232.

16.

Cyclosporine before PCI in Patients with Acute Myocardial Infarction.

Cung TT, Morel O, Cayla G, Rioufol G, Garcia-Dorado D, Angoulvant D, Bonnefoy-Cudraz E, Guérin P, Elbaz M, Delarche N, Coste P, Vanzetto G, Metge M, Aupetit JF, Jouve B, Motreff P, Tron C, Labeque JN, Steg PG, Cottin Y, Range G, Clerc J, Claeys MJ, Coussement P, Prunier F, Moulin F, Roth O, Belle L, Dubois P, Barragan P, Gilard M, Piot C, Colin P, De Poli F, Morice MC, Ider O, Dubois-Randé JL, Unterseeh T, Le Breton H, Béard T, Blanchard D, Grollier G, Malquarti V, Staat P, Sudre A, Elmer E, Hansson MJ, Bergerot C, Boussaha I, Jossan C, Derumeaux G, Mewton N, Ovize M.

N Engl J Med. 2015 Sep 10;373(11):1021-31. doi: 10.1056/NEJMoa1505489. Epub 2015 Aug 30.

17.

Mitochondrial bioenergetic alterations after focal traumatic brain injury in the immature brain.

Kilbaugh TJ, Karlsson M, Byro M, Bebee A, Ralston J, Sullivan S, Duhaime AC, Hansson MJ, Elmér E, Margulies SS.

Exp Neurol. 2015 Sep;271:136-44. doi: 10.1016/j.expneurol.2015.05.009. Epub 2015 May 28.

18.

Rationale and design of the Cyclosporine to ImpRove Clinical oUtcome in ST-elevation myocardial infarction patients (the CIRCUS trial).

Mewton N, Cung TT, Morel O, Cayla G, Bonnefoy-Cudraz E, Rioufol G, Angoulvant D, Guerin P, Elbaz M, Delarche N, Coste P, Vanzetto G, Metge M, Aupetit JF, Jouve B, Motreff P, Tron C, Labeque JN, Steg PG, Cottin Y, Range G, Clerc J, Coussement P, Prunier F, Moulin F, Roth O, Belle L, Dubois P, Barragan P, Gilard M, Piot C, Colin P, Morice MC, Monassier JP, Ider O, Dubois-Randé JL, Unterseeh T, Lebreton H, Beard T, Blanchard D, Grollier G, Malquarti V, Staat P, Sudre A, Hansson MJ, Elmer E, Boussaha I, Jossan C, Torner A, Claeys M, Garcia-Dorado D, Ovize M; CIRCUS Study Investigators.

Am Heart J. 2015 Jun;169(6):758-766.e6. doi: 10.1016/j.ahj.2015.02.020. Epub 2015 Mar 13.

19.

Differences in the profile of protection afforded by TRO40303 and mild hypothermia in models of cardiac ischemia/reperfusion injury.

Hansson MJ, Llwyd O, Morin D, de Paulis D, Arnoux T, Gouarné C, Koul S, Engblom H, Bordet T, Tissier R, Arheden H, Erlinge D, Halestrap AP, Berdeaux A, Pruss RM, Schaller S.

Eur J Pharmacol. 2015 Aug 5;760:7-19. doi: 10.1016/j.ejphar.2015.04.009. Epub 2015 Apr 17.

PMID:
25895640
20.

Mitochondrial dysfunction in blood cells from amyotrophic lateral sclerosis patients.

Ehinger JK, Morota S, Hansson MJ, Paul G, Elmér E.

J Neurol. 2015 Jun;262(6):1493-503. doi: 10.1007/s00415-015-7737-0. Epub 2015 Apr 18.

PMID:
25893255

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