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Items: 1 to 20 of 148


New chiral stationary phases for liquid chromatography based on small molecules: Development, enantioresolution evaluation and chiral recognition mechanisms.

Phyo YZ, Teixeira J, Tiritan ME, Cravo S, Palmeira A, Gales L, Silva AMS, Pinto MMM, Kijjoa A, Fernandes C.

Chirality. 2020 Jan;32(1):81-97. doi: 10.1002/chir.23142. Epub 2019 Nov 14.


Overcoming environmental problems of biocides: Synthetic bile acid derivatives as a sustainable alternative.

Neves AR, Almeida JR, Carvalhal F, Câmara A, Pereira S, Antunes J, Vasconcelos V, Pinto M, Silva ER, Sousa E, Correia-da-Silva M.

Ecotoxicol Environ Saf. 2020 Jan 15;187:109812. doi: 10.1016/j.ecoenv.2019.109812. Epub 2019 Oct 24.


Chalcone derivatives targeting mitosis: synthesis, evaluation of antitumor activity and lipophilicity.

Pinto P, Machado CM, Moreira J, Almeida JDP, Silva PMA, Henriques AC, Soares JX, Salvador JAR, Afonso C, Pinto M, Bousbaa H, Cidade H.

Eur J Med Chem. 2019 Dec 15;184:111752. doi: 10.1016/j.ejmech.2019.111752. Epub 2019 Oct 3.


Development and characterization of PLGA nanoparticles containing 1,3-dihydroxy-2-methylxanthone with improved antitumor activity on a human breast cancer cell line.

Teixeira M, Pedro M, Nascimento MSJ, Pinto MMM, Barbosa CM.

Pharm Dev Technol. 2019 Nov;24(9):1104-1114. doi: 10.1080/10837450.2019.1638398. Epub 2019 Jul 29.


A New Meroterpene, A New Benzofuran Derivative and Other Constituents from Cultures of the Marine Sponge-Associated Fungus Acremonium persicinum KUFA 1007 and Their Anticholinesterase Activities.

Alves AJS, Pereira JA, Dethoup T, Cravo S, Mistry S, Silva AMS, Pinto MMM, Kijjoa A.

Mar Drugs. 2019 Jun 25;17(6). pii: E379. doi: 10.3390/md17060379.


1,2-Dihydroxyxanthone: Effect on A375-C5 Melanoma Cell Growth Associated with Interference with THP-1 Human Macrophage Activity.

Silva V, Cerqueira F, Nazareth N, Medeiros R, Sarmento A, Sousa E, Pinto M.

Pharmaceuticals (Basel). 2019 Jun 4;12(2). pii: E85. doi: 10.3390/ph12020085.


Synthesis, Biological Evaluation, and In Silico Studies of Novel Aminated Xanthones as Potential p53-Activating Agents.

Lemos A, Gomes AS, Loureiro JB, Brandão P, Palmeira A, Pinto MMM, Saraiva L, Sousa ME.

Molecules. 2019 May 22;24(10). pii: E1975. doi: 10.3390/molecules24101975.


Chorea, Pruritus and Polycythemia: Looking for Clues.

Rodrigues V, Lopes C, Marcolino A, Pinto M.

Eur J Case Rep Intern Med. 2019 Feb 6;6(2):001039. doi: 10.12890/2019_001039. eCollection 2019.


Plasma membrane-localized TMEM16 proteins are indispensable for expression of CFTR.

Benedetto R, Ousingsawat J, Cabrita I, Pinto M, Lérias JR, Wanitchakool P, Schreiber R, Kunzelmann K.

J Mol Med (Berl). 2019 May;97(5):711-722. doi: 10.1007/s00109-019-01770-4. Epub 2019 Mar 26.


Antithrombotics from the Sea: Polysaccharides and Beyond.

Carvalhal F, Cristelo RR, Resende DISP, Pinto MMM, Sousa E, Correia-da-Silva M.

Mar Drugs. 2019 Mar 16;17(3). pii: E170. doi: 10.3390/md17030170. Review.


Chiral Stationary Phases for Liquid Chromatography: Recent Developments.

Teixeira J, Tiritan ME, Pinto MMM, Fernandes C.

Molecules. 2019 Feb 28;24(5). pii: E865. doi: 10.3390/molecules24050865. Review.


Synthetic Chiral Derivatives of Xanthones: Biological Activities and Enantioselectivity Studies.

Fernandes C, Carraro ML, Ribeiro J, Araújo J, Tiritan ME, Pinto MMM.

Molecules. 2019 Feb 22;24(4). pii: E791. doi: 10.3390/molecules24040791. Review.


Synthesis of New Proteomimetic Quinazolinone Alkaloids and Evaluation of Their Neuroprotective and Antitumor Effects.

Long S, Resende DISP, Kijjoa A, Silva AMS, Fernandes R, Xavier CPR, Vasconcelos MH, Sousa E, Pinto MMM.

Molecules. 2019 Feb 1;24(3). pii: E534. doi: 10.3390/molecules24030534.


Isolation and Potential Biological Applications of Haloaryl Secondary Metabolites from Macroalgae.

Jesus A, Correia-da-Silva M, Afonso C, Pinto M, Cidade H.

Mar Drugs. 2019 Jan 22;17(2). pii: E73. doi: 10.3390/md17020073. Review.


Discovery of a New Xanthone against Glioma: Synthesis and Development of (Pro)liposome Formulations.

Alves A, Correia-da-Silva M, Nunes C, Campos J, Sousa E, Silva PMA, Bousbaa H, Rodrigues F, Ferreira D, Costa PC, Pinto M.

Molecules. 2019 Jan 23;24(3). pii: E409. doi: 10.3390/molecules24030409.


New inhibitor of the TAp73 interaction with MDM2 and mutant p53 with promising antitumor activity against neuroblastoma.

Gomes S, Raimundo L, Soares J, Loureiro JB, Leão M, Ramos H, Monteiro MN, Lemos A, Moreira J, Pinto M, Chlapek P, Veselska R, Sousa E, Saraiva L.

Cancer Lett. 2019 Apr 1;446:90-102. doi: 10.1016/j.canlet.2019.01.014. Epub 2019 Jan 19.


Chiral Derivatives of Xanthones with Antimicrobial Activity.

Araújo J, Fernandes C, Pinto M, Tiritan ME.

Molecules. 2019 Jan 16;24(2). pii: E314. doi: 10.3390/molecules24020314. Review.


Structures, Activities and Drug-Likeness of Anti-Infective Xanthone Derivatives Isolated from the Marine Environment: A Review.

Loureiro DRP, Soares JX, Costa JC, Magalhães ÁF, Azevedo CMG, Pinto MMM, Afonso CMM.

Molecules. 2019 Jan 10;24(2). pii: E243. doi: 10.3390/molecules24020243. Review.


Erubescensoic Acid, a New Polyketide and a Xanthonopyrone SPF-3059-26 from the Culture of the Marine Sponge-Associated Fungus Penicillium erubescens KUFA 0220 and Antibacterial Activity Evaluation of Some of Its Constituents.

Kumla D, Dethoup T, Gales L, Pereira JA, Freitas-Silva J, Costa PM, Silva AMS, Pinto MMM, Kijjoa A.

Molecules. 2019 Jan 8;24(1). pii: E208. doi: 10.3390/molecules24010208.


Carboxyxanthones: Bioactive Agents and Molecular Scaffold for Synthesis of Analogues and Derivatives.

Ribeiro J, Veloso C, Fernandes C, Tiritan ME, Pinto MMM.

Molecules. 2019 Jan 5;24(1). pii: E180. doi: 10.3390/molecules24010180. Review.

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