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Items: 6


SNAP-25b-deficiency increases insulin secretion and changes spatiotemporal profile of Ca2+oscillations in β cell networks.

Daraio T, Bombek LK, Gosak M, Valladolid-Acebes I, Klemen MS, Refai E, Berggren PO, Brismar K, Rupnik MS, Bark C.

Sci Rep. 2017 Aug 10;7(1):7744. doi: 10.1038/s41598-017-08082-y.


The triggering pathway to insulin secretion: Functional similarities and differences between the human and the mouse β cells and their translational relevance.

Skelin Klemen M, Dolenšek J, Slak Rupnik M, Stožer A.

Islets. 2017 Nov 2;9(6):109-139. doi: 10.1080/19382014.2017.1342022. Epub 2017 Jun 29. Review.


Membrane Potential and Calcium Dynamics in Beta Cells from Mouse Pancreas Tissue Slices: Theory, Experimentation, and Analysis.

Dolenšek J, Špelič D, Klemen MS, Žalik B, Gosak M, Rupnik MS, Stožer A.

Sensors (Basel). 2015 Oct 28;15(11):27393-419. doi: 10.3390/s151127393. Review.


Characterization of pancreatic NMDA receptors as possible drug targets for diabetes treatment.

Marquard J, Otter S, Welters A, Stirban A, Fischer A, Eglinger J, Herebian D, Kletke O, Klemen MS, Stožer A, Wnendt S, Piemonti L, Köhler M, Ferrer J, Thorens B, Schliess F, Rupnik MS, Heise T, Berggren PO, Klöcker N, Meissner T, Mayatepek E, Eberhard D, Kragl M, Lammert E.

Nat Med. 2015 Apr;21(4):363-72. doi: 10.1038/nm.3822. Epub 2015 Mar 16.


The relationship between membrane potential and calcium dynamics in glucose-stimulated beta cell syncytium in acute mouse pancreas tissue slices.

Dolenšek J, Stožer A, Skelin Klemen M, Miller EW, Slak Rupnik M.

PLoS One. 2013 Dec 6;8(12):e82374. doi: 10.1371/journal.pone.0082374. eCollection 2013.


Rab3a is critical for trapping alpha-MSH granules in the high Ca²⁺-affinity pool by preventing constitutive exocytosis.

Sedej S, Klemen MS, Schlüter OM, Rupnik MS.

PLoS One. 2013 Oct 21;8(10):e78883. doi: 10.1371/journal.pone.0078883. eCollection 2013.

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