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Items: 1 to 20 of 25

1.

Redox Signaling from Mitochondria: Signal Propagation and Its Targets.

Ježek P, Holendová B, Plecitá-Hlavatá L.

Biomolecules. 2020 Jan 6;10(1). pii: E93. doi: 10.3390/biom10010093. Review.

2.

Potential of Mitochondria-Targeted Antioxidants to Prevent Oxidative Stress in Pancreatic β-cells.

Plecitá-Hlavatá L, Engstová H, Ježek J, Holendová B, Tauber J, Petrásková L, Křen V, Ježek P.

Oxid Med Cell Longev. 2019 May 21;2019:1826303. doi: 10.1155/2019/1826303. eCollection 2019.

3.

Mitochondrial cristae narrowing upon higher 2-oxoglutarate load.

Dlasková A, Špaček T, Engstová H, Špačková J, Schröfel A, Holendová B, Smolková K, Plecitá-Hlavatá L, Ježek P.

Biochim Biophys Acta Bioenerg. 2019 Aug 1;1860(8):659-678. doi: 10.1016/j.bbabio.2019.06.015. Epub 2019 Jun 25.

PMID:
31247171
4.

Contribution of Oxidative Stress and Impaired Biogenesis of Pancreatic β-Cells to Type 2 Diabetes.

Ježek P, Jabůrek M, Plecitá-Hlavatá L.

Antioxid Redox Signal. 2019 Oct 1;31(10):722-751. doi: 10.1089/ars.2018.7656. Epub 2019 Jan 23.

5.

Aglycemic HepG2 Cells Switch From Aminotransferase Glutaminolytic Pathway of Pyruvate Utilization to Complete Krebs Cycle at Hypoxia.

Ježek J, Plecitá-Hlavatá L, Ježek P.

Front Endocrinol (Lausanne). 2018 Oct 26;9:637. doi: 10.3389/fendo.2018.00637. eCollection 2018.

6.

Fatty Acid-Stimulated Insulin Secretion vs. Lipotoxicity.

Ježek P, Jabůrek M, Holendová B, Plecitá-Hlavatá L.

Molecules. 2018 Jun 19;23(6). pii: E1483. doi: 10.3390/molecules23061483. Review.

7.

3D super-resolution microscopy reflects mitochondrial cristae alternations and mtDNA nucleoid size and distribution.

Dlasková A, Engstová H, Špaček T, Kahancová A, Pavluch V, Smolková K, Špačková J, Bartoš M, Hlavatá LP, Ježek P.

Biochim Biophys Acta Bioenerg. 2018 Sep;1859(9):829-844. doi: 10.1016/j.bbabio.2018.04.013. Epub 2018 May 1.

8.

Metabolic Reprogramming and Redox Signaling in Pulmonary Hypertension.

Plecitá-Hlavatá L, D'alessandro A, El Kasmi K, Li M, Zhang H, Ježek P, Stenmark KR.

Adv Exp Med Biol. 2017;967:241-260. doi: 10.1007/978-3-319-63245-2_14.

PMID:
29047090
9.

Metabolic and Proliferative State of Vascular Adventitial Fibroblasts in Pulmonary Hypertension Is Regulated Through a MicroRNA-124/PTBP1 (Polypyrimidine Tract Binding Protein 1)/Pyruvate Kinase Muscle Axis.

Zhang H, Wang D, Li M, Plecitá-Hlavatá L, D'Alessandro A, Tauber J, Riddle S, Kumar S, Flockton A, McKeon BA, Frid MG, Reisz JA, Caruso P, El Kasmi KC, Ježek P, Morrell NW, Hu CJ, Stenmark KR.

Circulation. 2017 Dec 19;136(25):2468-2485. doi: 10.1161/CIRCULATIONAHA.117.028069. Epub 2017 Sep 26.

10.

Hallmarks of Pulmonary Hypertension: Mesenchymal and Inflammatory Cell Metabolic Reprogramming.

D'Alessandro A, El Kasmi KC, Plecitá-Hlavatá L, Ježek P, Li M, Zhang H, Gupte SA, Stenmark KR.

Antioxid Redox Signal. 2018 Jan 20;28(3):230-250. doi: 10.1089/ars.2017.7217. Epub 2017 Aug 14. Review.

11.

Integration of superoxide formation and cristae morphology for mitochondrial redox signaling.

Plecitá-Hlavatá L, Ježek P.

Int J Biochem Cell Biol. 2016 Nov;80:31-50. doi: 10.1016/j.biocel.2016.09.010. Epub 2016 Sep 15. Review.

PMID:
27640755
12.

Metabolic Reprogramming Regulates the Proliferative and Inflammatory Phenotype of Adventitial Fibroblasts in Pulmonary Hypertension Through the Transcriptional Corepressor C-Terminal Binding Protein-1.

Li M, Riddle S, Zhang H, D'Alessandro A, Flockton A, Serkova NJ, Hansen KC, Moldovan R, McKeon BA, Frid M, Kumar S, Li H, Liu H, Caánovas A, Medrano JF, Thomas MG, Iloska D, Plecitá-Hlavatá L, Ježek P, Pullamsetti S, Fini MA, El Kasmi KC, Zhang Q, Stenmark KR.

Circulation. 2016 Oct 11;134(15):1105-1121. Epub 2016 Aug 25. Erratum in: Circulation. 2019 Jan 8;139(2):e1. Moldvan, Radu [corrected to Moldovan, Radu].

13.

Hypoxic HepG2 cell adaptation decreases ATP synthase dimers and ATP production in inflated cristae by mitofilin down-regulation concomitant to MICOS clustering.

Plecitá-Hlavatá L, Engstová H, Alán L, Špaček T, Dlasková A, Smolková K, Špačková J, Tauber J, Strádalová V, Malínský J, Lessard M, Bewersdorf J, Ježek P.

FASEB J. 2016 May;30(5):1941-57. doi: 10.1096/fj.201500176. Epub 2016 Feb 17.

PMID:
26887443
14.

Constitutive Reprogramming of Fibroblast Mitochondrial Metabolism in Pulmonary Hypertension.

Plecitá-Hlavatá L, Tauber J, Li M, Zhang H, Flockton AR, Pullamsetti SS, Chelladurai P, D'Alessandro A, El Kasmi KC, Ježek P, Stenmark KR.

Am J Respir Cell Mol Biol. 2016 Jul;55(1):47-57. doi: 10.1165/rcmb.2015-0142OC.

15.

Aglycemia keeps mitochondrial oxidative phosphorylation under hypoxic conditions in HepG2 cells.

Plecitá-Hlavatá L, Ježek J, Ježek P.

J Bioenerg Biomembr. 2015 Dec;47(6):467-76. doi: 10.1007/s10863-015-9628-6. Epub 2015 Oct 8.

PMID:
26449597
16.

Distribution of mitochondrial DNA nucleoids inside the linear tubules vs. bulk parts of mitochondrial network as visualized by 4Pi microscopy.

Dlasková A, Engstová H, Plecitá-Hlavatá L, Lessard M, Alán L, Reguera DP, Jabůrek M, Ježek P.

J Bioenerg Biomembr. 2015 Jun;47(3):255-63. doi: 10.1007/s10863-015-9610-3. Epub 2015 Apr 2.

PMID:
25833036
17.

Redox homeostasis in pancreatic β cells.

Ježek P, Dlasková A, Plecitá-Hlavatá L.

Oxid Med Cell Longev. 2012;2012:932838. doi: 10.1155/2012/932838. Epub 2012 Dec 13. Review.

18.

Distribution of mitochondrial nucleoids upon mitochondrial network fragmentation and network reintegration in HEPG2 cells.

Tauber J, Dlasková A, Šantorová J, Smolková K, Alán L, Špaček T, Plecitá-Hlavatá L, Jabůrek M, Ježek P.

Int J Biochem Cell Biol. 2013 Mar;45(3):593-603. doi: 10.1016/j.biocel.2012.11.019. Epub 2012 Dec 7.

PMID:
23220174
19.

Waves of gene regulation suppress and then restore oxidative phosphorylation in cancer cells.

Smolková K, Plecitá-Hlavatá L, Bellance N, Benard G, Rossignol R, Ježek P.

Int J Biochem Cell Biol. 2011 Jul;43(7):950-68. doi: 10.1016/j.biocel.2010.05.003. Epub 2010 May 10. Review.

PMID:
20460169
20.

4Pi microscopy reveals an impaired three-dimensional mitochondrial network of pancreatic islet beta-cells, an experimental model of type-2 diabetes.

Dlasková A, Spacek T, Santorová J, Plecitá-Hlavatá L, Berková Z, Saudek F, Lessard M, Bewersdorf J, Jezek P.

Biochim Biophys Acta. 2010 Jun-Jul;1797(6-7):1327-41. doi: 10.1016/j.bbabio.2010.02.003. Epub 2010 Feb 6.

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