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Items: 1 to 20 of 270


Single-sample landscape entropy reveals the imminent phase transition during disease progression.

Liu R, Chen P, Chen L.

Bioinformatics. 2020 Jan 14. pii: btz935. doi: 10.1093/bioinformatics/btz935. [Epub ahead of print] No abstract available.


Oleic Acid Attenuates Ang II (Angiotensin II)-Induced Cardiac Remodeling by Inhibiting FGF23 (Fibroblast Growth Factor 23) Expression in Mice.

Liu T, Wen H, Li H, Xu H, Xiao N, Liu R, Chen L, Sun Y, Song L, Bai C, Ge J, Zhang Y, Chen J.

Hypertension. 2020 Jan 13:HYPERTENSIONAHA11914167. doi: 10.1161/HYPERTENSIONAHA.119.14167. [Epub ahead of print]


Associating lncRNAs with small molecules via bilevel optimization reveals cancer-related lncRNAs.

Wang Y, Chen S, Chen L, Wang Y.

PLoS Comput Biol. 2019 Dec 26;15(12):e1007540. doi: 10.1371/journal.pcbi.1007540. eCollection 2019 Dec.


Chronic hepatitis B: dynamic change in Traditional Chinese Medicine syndrome by dynamic network biomarkers.

Lu Y, Fang Z, Zeng T, Li M, Chen Q, Zhang H, Zhou Q, Hu Y, Chen L, Su S.

Chin Med. 2019 Nov 21;14:52. doi: 10.1186/s13020-019-0275-4. eCollection 2019.


A novel network control model for identifying personalized driver genes in cancer.

Guo WF, Zhang SW, Zeng T, Li Y, Gao J, Chen L.

PLoS Comput Biol. 2019 Nov 25;15(11):e1007520. doi: 10.1371/journal.pcbi.1007520. eCollection 2019 Nov.


Author Correction: Competitive endogenous RNA is an intrinsic component of EMT regulatory circuits and modulates EMT.

Liu Y, Xue M, Du S, Feng W, Zhang K, Zhang L, Liu H, Jia G, Wu L, Hu X, Chen L, Wang P.

Nat Commun. 2019 Nov 20;10(1):5344. doi: 10.1038/s41467-019-13370-4.


Nerve Injury-Induced Neuronal PAP-I Maintains Neuropathic Pain by Activating Spinal Microglia.

Li J, Shi H, Liu H, Dong F, Liu Z, Lu Y, Chen L, Bao L, Zhang X.

J Neurosci. 2020 Jan 8;40(2):297-310. doi: 10.1523/JNEUROSCI.1414-19.2019. Epub 2019 Nov 19.


Quantifying pluripotency landscape of cell differentiation from scRNA-seq data by continuous birth-death process.

Shi J, Li T, Chen L, Aihara K.

PLoS Comput Biol. 2019 Nov 13;15(11):e1007488. doi: 10.1371/journal.pcbi.1007488. eCollection 2019 Nov.


Network control principles for identifying personalized driver genes in cancer.

Guo WF, Zhang SW, Zeng T, Akutsu T, Chen L.

Brief Bioinform. 2019 Nov 10. pii: bbz089. doi: 10.1093/bib/bbz089. [Epub ahead of print]


Single-sample landscape entropy reveals the imminent phase transition during disease progression.

Liu R, Chen P, Chen L.

Bioinformatics. 2019 Oct 9. pii: btz758. doi: 10.1093/bioinformatics/btz758. [Epub ahead of print]


Computational systems biology for omics data analysis.

Chen L.

J Mol Cell Biol. 2019 Aug 19;11(8):631-632. doi: 10.1093/jmcb/mjz095. No abstract available.


Hierarchical graphical model reveals HFR1 bridging circadian rhythm and flower development in Arabidopsis thaliana.

Duren Z, Wang Y, Wang J, Zhao XM, Lv L, Li X, Liu J, Zhu XG, Chen L, Wang Y.

NPJ Syst Biol Appl. 2019 Aug 12;5:28. doi: 10.1038/s41540-019-0106-3. eCollection 2019.


Revealing dynamic regulations and the related key proteins of myeloma-initiating cells by integrating experimental data into a systems biological model.

Zhang L, Liu G, Kong M, Li T, Wu D, Zhou X, Yang C, Xia L, Yang Z, Chen L.

Bioinformatics. 2019 Jul 26. pii: btz542. doi: 10.1093/bioinformatics/btz542. [Epub ahead of print]


Branched-Chain Amino Acid Metabolic Reprogramming Orchestrates Drug Resistance to EGFR Tyrosine Kinase Inhibitors.

Wang Y, Zhang J, Ren S, Sun D, Huang HY, Wang H, Jin Y, Li F, Zheng C, Yang L, Deng L, Jiang Z, Jiang T, Han X, Hou S, Guo C, Li F, Gao D, Qin J, Gao D, Chen L, Lin SH, Wong KK, Li C, Hu L, Zhou C, Ji H.

Cell Rep. 2019 Jul 9;28(2):512-525.e6. doi: 10.1016/j.celrep.2019.06.026.


Targeted genetic screening in mice through haploid embryonic stem cells identifies critical genes in bone development.

Bai M, Han Y, Wu Y, Liao J, Li L, Wang L, Li Q, Xing W, Chen L, Zou W, Li J.

PLoS Biol. 2019 Jul 2;17(7):e3000350. doi: 10.1371/journal.pbio.3000350. eCollection 2019 Jul.


Identifying pre-disease signals before metabolic syndrome in mice by dynamical network biomarkers.

Koizumi K, Oku M, Hayashi S, Inujima A, Shibahara N, Chen L, Igarashi Y, Tobe K, Saito S, Kadowaki M, Aihara K.

Sci Rep. 2019 Jun 24;9(1):8767. doi: 10.1038/s41598-019-45119-w.


The Effects of Graded Levels of Calorie Restriction: XIV. Global Metabolomics Screen Reveals Brown Adipose Tissue Changes in Amino Acids, Catecholamines, and Antioxidants After Short-Term Restriction in C57BL/6 Mice.

Green CL, Mitchell SE, Derous D, Wang Y, Chen L, Han JJ, Promislow DEL, Lusseau D, Douglas A, Speakman JR.

J Gerontol A Biol Sci Med Sci. 2020 Jan 20;75(2):218-229. doi: 10.1093/gerona/glz023.


Predicting protein-ligand interactions based on bow-pharmacological space and Bayesian additive regression trees.

Li L, Koh CC, Reker D, Brown JB, Wang H, Lee NK, Liow HH, Dai H, Fan HM, Chen L, Wei DQ.

Sci Rep. 2019 May 22;9(1):7703. doi: 10.1038/s41598-019-43125-6.


High-Order Correlation Integration for Single-Cell or Bulk RNA-seq Data Analysis.

Tang H, Zeng T, Chen L.

Front Genet. 2019 Apr 26;10:371. doi: 10.3389/fgene.2019.00371. eCollection 2019.


Systems biology intertwines with single cell and AI.

Wang Y, Zhang XS, Chen L.

BMC Bioinformatics. 2019 May 1;20(Suppl 7):204. doi: 10.1186/s12859-019-2731-7.

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