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Items: 1 to 20 of 145


A Lassa Virus Live-Attenuated Vaccine Candidate Based on Rearrangement of the Intergenic Region.

Cai Y, Iwasaki M, Motooka D, Liu DX, Yu S, Cooper K, Hart R, Adams R, Burdette T, Postnikova EN, Kurtz J, St Claire M, Ye C, Kuhn JH, Martínez-Sobrido L, de la Torre JC.

mBio. 2020 Mar 24;11(2). pii: e00186-20. doi: 10.1128/mBio.00186-20.


Snake Deltavirus Utilizes Envelope Proteins of Different Viruses To Generate Infectious Particles.

Szirovicza L, Hetzel U, Kipar A, Martinez-Sobrido L, Vapalahti O, Hepojoki J.

mBio. 2020 Mar 17;11(2). pii: e03250-19. doi: 10.1128/mBio.03250-19.


A Lassa Fever Live-Attenuated Vaccine Based on Codon Deoptimization of the Viral Glycoprotein Gene.

Cai Y, Ye C, Cheng B, Nogales A, Iwasaki M, Yu S, Cooper K, Liu DX, Hart R, Adams R, Brady T, Postnikova EN, Kurtz J, St Claire M, Kuhn JH, de la Torre JC, Martínez-Sobrido L.

mBio. 2020 Feb 25;11(1). pii: e00039-20. doi: 10.1128/mBio.00039-20.


A Broad and Potent H1-Specific Human Monoclonal Antibody Produced in Plants Prevents Influenza Virus Infection and Transmission in Guinea Pigs.

Park JG, Ye C, Piepenbrink MS, Nogales A, Wang H, Shuen M, Meyers AJ, Martinez-Sobrido L, Kobie JJ.

Viruses. 2020 Feb 2;12(2). pii: E167. doi: 10.3390/v12020167.


Increasing the Safety Profile of the Master Donor Live Attenuated Influenza Vaccine.

Hilimire TA, Nogales A, Chiem K, Ortego J, Martinez-Sobrido L.

Pathogens. 2020 Jan 29;9(2). pii: E86. doi: 10.3390/pathogens9020086.


In vivo rescue of recombinant Zika virus from an infectious cDNA clone and its implications in vaccine development.

Ávila-Pérez G, Nogales A, Park JG, Vasquez DM, Dean DA, Barravecchia M, Perez DR, Almazán F, Martínez-Sobrido L.

Sci Rep. 2020 Jan 16;10(1):512. doi: 10.1038/s41598-020-57545-2.


Identification and Characterization of Novel Compounds with Broad-Spectrum Antiviral Activity against Influenza A and B Viruses.

Park JG, Ávila-Pérez G, Nogales A, Blanco-Lobo P, de la Torre JC, Martínez-Sobrido L.

J Virol. 2020 Mar 17;94(7). pii: e02149-19. doi: 10.1128/JVI.02149-19. Print 2020 Mar 17.


Functional Characterization and Direct Comparison of Influenza A, B, C, and D NS1 Proteins in vitro and in vivo.

Nogales A, Aydillo T, Ávila-Pérez G, Escalera A, Chiem K, Cadagan R, DeDiego ML, Li F, García-Sastre A, Martínez-Sobrido L.

Front Microbiol. 2019 Dec 17;10:2862. doi: 10.3389/fmicb.2019.02862. eCollection 2019.


A natural polymorphism in Zika virus NS2A protein responsible of virulence in mice.

Ávila-Pérez G, Nogales A, Park JG, Márquez-Jurado S, Iborra FJ, Almazan F, Martínez-Sobrido L.

Sci Rep. 2019 Dec 27;9(1):19968. doi: 10.1038/s41598-019-56291-4.


A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity.

Cubitt B, Ortiz-Riano E, Cheng BY, Kim YJ, Yeh CD, Chen CZ, Southall NOE, Zheng W, Martinez-Sobrido L, de la Torre JC.

Antiviral Res. 2020 Jan;173:104667. doi: 10.1016/j.antiviral.2019.104667. Epub 2019 Nov 28.


A Live Attenuated Influenza Vaccine Elicits Enhanced Heterologous Protection When the Internal Genes of the Vaccine Are Matched to Those of the Challenge Virus.

Smith A, Rodriguez L, El Ghouayel M, Nogales A, Chamberlain JM, Sortino K, Reilly E, Feng C, Topham DJ, Martínez-Sobrido L, Dewhurst S.

J Virol. 2020 Jan 31;94(4). pii: e01065-19. doi: 10.1128/JVI.01065-19. Print 2020 Jan 31.


Comparative Study of the Temperature Sensitive, Cold Adapted and Attenuated Mutations Present in the Master Donor Viruses of the Two Commercial Human Live Attenuated Influenza Vaccines.

Rodriguez L, Blanco-Lobo P, Reilly EC, Maehigashi T, Nogales A, Smith A, Topham DJ, Dewhurst S, Kim B, Martínez-Sobrido L.

Viruses. 2019 Oct 10;11(10). pii: E928. doi: 10.3390/v11100928.


A Bivalent Live-Attenuated Vaccine for the Prevention of Equine Influenza Virus.

Blanco-Lobo P, Rodriguez L, Reedy S, Oladunni FS, Nogales A, Murcia PR, Chambers TM, Martinez-Sobrido L.

Viruses. 2019 Oct 11;11(10). pii: E933. doi: 10.3390/v11100933.


Influenza Viruses in Mice: Deep Sequencing Analysis of Serial Passage and Effects of Sialic Acid Structural Variation.

Wasik BR, Voorhees IEH, Barnard KN, Alford-Lawrence BK, Weichert WS, Hood G, Nogales A, Martínez-Sobrido L, Holmes EC, Parrish CR.

J Virol. 2019 Nov 13;93(23). pii: e01039-19. doi: 10.1128/JVI.01039-19. Print 2019 Dec 1.


A Luciferase-fluorescent Reporter Influenza Virus for Live Imaging and Quantification of Viral Infection.

Chiem K, Rangel-Moreno J, Nogales A, Martinez-Sobrido L.

J Vis Exp. 2019 Aug 14;(150). doi: 10.3791/59890.


Interferon-Induced Protein 44 Interacts with Cellular FK506-Binding Protein 5, Negatively Regulates Host Antiviral Responses, and Supports Virus Replication.

DeDiego ML, Nogales A, Martinez-Sobrido L, Topham DJ.

mBio. 2019 Aug 27;10(4). pii: e01839-19. doi: 10.1128/mBio.01839-19.


Novel Functions of IFI44L as a Feedback Regulator of Host Antiviral Responses.

DeDiego ML, Martinez-Sobrido L, Topham DJ.

J Virol. 2019 Oct 15;93(21). pii: e01159-19. doi: 10.1128/JVI.01159-19. Print 2019 Nov 1.


Onward transmission of viruses: how do viruses emerge to cause epidemics after spillover?

Wasik BR, de Wit E, Munster V, Lloyd-Smith JO, Martinez-Sobrido L, Parrish CR.

Philos Trans R Soc Lond B Biol Sci. 2019 Sep 30;374(1782):20190017. doi: 10.1098/rstb.2019.0017. Epub 2019 Aug 12.


Peptides Derived from the Tight Junction Protein CLDN1 Disrupt the Skin Barrier and Promote Responsiveness to an Epicutaneous Vaccine.

Brewer MG, Anderson EA, Pandya RP, De Benedetto A, Yoshida T, Hilimire TA, Martinez-Sobrido L, Beck LA, Miller BL.

J Invest Dermatol. 2020 Feb;140(2):361-369.e3. doi: 10.1016/j.jid.2019.06.145. Epub 2019 Aug 2.


Rescue of Recombinant Zika Virus from a Bacterial Artificial Chromosome cDNA Clone.

Ávila-Pérez G, Park JG, Nogales A, Almazán F, Martínez-Sobrido L.

J Vis Exp. 2019 Jun 24;(148). doi: 10.3791/59537.


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