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Items: 1 to 20 of 59


Measurement of Microtubule Dynamics by Spinning Disk Microscopy in Monopolar Mitotic Spindles.

Movsisyan N, Pardo LA.

J Vis Exp. 2019 Nov 15;(153). doi: 10.3791/60478.


New Structures and Gating of Voltage-Dependent Potassium (Kv) Channels and Their Relatives: A Multi-Domain and Dynamic Question.

Barros F, Pardo LA, Domínguez P, Sierra LM, de la Peña P.

Int J Mol Sci. 2019 Jan 10;20(2). pii: E248. doi: 10.3390/ijms20020248. Review.


Synthesis of novel purpurealidin analogs and evaluation of their effect on the cancer-relevant potassium channel KV10.1.

Moreels L, Bhat C, Voráčová M, Peigneur S, Goovaerts H, Mäki-Lohiluoma E, Zahed F, Pardo LA, Yli-Kauhaluoma J, Kiuru P, Tytgat J.

PLoS One. 2017 Dec 8;12(12):e0188811. doi: 10.1371/journal.pone.0188811. eCollection 2017.


APETx4, a Novel Sea Anemone Toxin and a Modulator of the Cancer-Relevant Potassium Channel KV10.1.

Moreels L, Peigneur S, Galan DT, De Pauw E, Béress L, Waelkens E, Pardo LA, Quinton L, Tytgat J.

Mar Drugs. 2017 Sep 13;15(9). pii: E287. doi: 10.3390/md15090287.


Alternating pH landscapes shape epithelial cancer initiation and progression: Focus on pancreatic cancer.

Pedersen SF, Novak I, Alves F, Schwab A, Pardo LA.

Bioessays. 2017 Jun;39(6). doi: 10.1002/bies.201600253. Epub 2017 Apr 25. Review.


A new mechanism of voltage-dependent gating exposed by KV10.1 channels interrupted between voltage sensor and pore.

Tomczak AP, Fernández-Trillo J, Bharill S, Papp F, Panyi G, Stühmer W, Isacoff EY, Pardo LA.

J Gen Physiol. 2017 May 1;149(5):577-593. doi: 10.1085/jgp.201611742. Epub 2017 Mar 30.


In vivo imaging of tumour xenografts with an antibody targeting the potassium channel Kv10.1.

Napp J, Pardo LA, Hartung F, Tietze LF, Stühmer W, Alves F.

Eur Biophys J. 2016 Oct;45(7):721-733. Epub 2016 Jul 21.


Ion channels, transporters and cancer ("INCA2015"): an international meeting in honor of Prof. Dr. Walter Stühmer.

Djamgoz MB, Pardo LA.

Eur Biophys J. 2016 Oct;45(7):581-583. No abstract available.


Guiding TRAIL to cancer cells through Kv10.1 potassium channel overcomes resistance to doxorubicin.

Hartung F, Pardo LA.

Eur Biophys J. 2016 Oct;45(7):709-719. Epub 2016 Jun 27.


Gating Modulation of the Tumor-Related Kv10.1 Channel by Mibefradil.

Gómez-Lagunas F, Carrillo E, Pardo LA, Stühmer W.

J Cell Physiol. 2017 Aug;232(8):2019-2032. doi: 10.1002/jcp.25448. Epub 2017 Jan 11.


Cyclic expression of the voltage-gated potassium channel KV10.1 promotes disassembly of the primary cilium.

Sánchez A, Urrego D, Pardo LA.

EMBO Rep. 2016 May;17(5):708-23. doi: 10.15252/embr.201541082. Epub 2016 Apr 20.


Periodic expression of Kv10.1 driven by pRb/E2F1 contributes to G2/M progression of cancer and non-transformed cells.

Urrego D, Movsisyan N, Ufartes R, Pardo LA.

Cell Cycle. 2016;15(6):799-811. doi: 10.1080/15384101.2016.1138187.


SK3 Channel Overexpression in Mice Causes Hippocampal Shrinkage Associated with Cognitive Impairments.

Martin S, Lazzarini M, Dullin C, Balakrishnan S, Gomes FV, Ninkovic M, El Hady A, Pardo LA, Stühmer W, Del-Bel E.

Mol Neurobiol. 2017 Mar;54(2):1078-1091. doi: 10.1007/s12035-015-9680-6. Epub 2016 Jan 23.


Kv10.1 K(+) channel: from physiology to cancer.

Ouadid-Ahidouch H, Ahidouch A, Pardo LA.

Pflugers Arch. 2016 May;468(5):751-62. doi: 10.1007/s00424-015-1784-3. Epub 2016 Jan 8. Review.


Alternatively Spliced Isoforms of KV10.1 Potassium Channels Modulate Channel Properties and Can Activate Cyclin-dependent Kinase in Xenopus Oocytes.

Ramos Gomes F, Romaniello V, Sánchez A, Weber C, Narayanan P, Psol M, Pardo LA.

J Biol Chem. 2015 Dec 18;290(51):30351-65. doi: 10.1074/jbc.M115.668749. Epub 2015 Oct 30.


CD133 Expression Is Not Synonymous to Immunoreactivity for AC133 and Fluctuates throughout the Cell Cycle in Glioma Stem-Like Cells.

Barrantes-Freer A, Renovanz M, Eich M, Braukmann A, Sprang B, Spirin P, Pardo LA, Giese A, Kim EL.

PLoS One. 2015 Jun 18;10(6):e0130519. doi: 10.1371/journal.pone.0130519. eCollection 2015.


Voltage-dependent gating of KCNH potassium channels lacking a covalent link between voltage-sensing and pore domains.

Lörinczi É, Gómez-Posada JC, de la Peña P, Tomczak AP, Fernández-Trillo J, Leipscher U, Stühmer W, Barros F, Pardo LA.

Nat Commun. 2015 Mar 30;6:6672. doi: 10.1038/ncomms7672.


KV 10.1 opposes activity-dependent increase in Ca²⁺ influx into the presynaptic terminal of the parallel fibre-Purkinje cell synapse.

Mortensen LS, Schmidt H, Farsi Z, Barrantes-Freer A, Rubio ME, Ufartes R, Eilers J, Sakaba T, Stühmer W, Pardo LA.

J Physiol. 2015 Jan 1;593(1):181-96. doi: 10.1113/jphysiol.2014.281600. Epub 2014 Nov 25.


Potassium channels in cell cycle and cell proliferation.

Urrego D, Tomczak AP, Zahed F, Stühmer W, Pardo LA.

Philos Trans R Soc Lond B Biol Sci. 2014 Feb 3;369(1638):20130094. doi: 10.1098/rstb.2013.0094. Print 2014 Mar 19. Review.

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