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Items: 15


Synthetic Lethality Screening Identifies FDA-Approved Drugs that Overcome ATP7B-Mediated Tolerance of Tumor Cells to Cisplatin.

Mariniello M, Petruzzelli R, Wanderlingh LG, La Montagna R, Carissimo A, Pane F, Amoresano A, Ilyechova EY, Galagudza MM, Catalano F, Crispino R, Puchkova LV, Medina DL, Polishchuk RS.

Cancers (Basel). 2020 Mar 6;12(3). pii: E608. doi: 10.3390/cancers12030608.


Case of Early-Onset Parkinson's Disease in a Heterozygous Mutation Carrier of the ATP7B Gene.

Ilyechova EY, Miliukhina IV, Karpenko MN, Orlov IA, Puchkova LV, Samsonov SA.

J Pers Med. 2019 Aug 17;9(3). pii: E41. doi: 10.3390/jpm9030041.


Silver Ions as a Tool for Understanding Different Aspects of Copper Metabolism.

Puchkova LV, Broggini M, Polishchuk EV, Ilyechova EY, Polishchuk RS.

Nutrients. 2019 Jun 17;11(6). pii: E1364. doi: 10.3390/nu11061364. Review.


CRISP-R/Cas9 Mediated Deletion of Copper Transport Genes CTR1 and DMT1 in NSCLC Cell Line H1299. Biological and Pharmacological Consequences.

Ilyechova EY, Bonaldi E, Orlov IA, Skomorokhova EA, Puchkova LV, Broggini M.

Cells. 2019 Apr 6;8(4). pii: E322. doi: 10.3390/cells8040322.


Activation of Autophagy, Observed in Liver Tissues From Patients With Wilson Disease and From ATP7B-Deficient Animals, Protects Hepatocytes From Copper-Induced Apoptosis.

Polishchuk EV, Merolla A, Lichtmannegger J, Romano A, Indrieri A, Ilyechova EY, Concilli M, De Cegli R, Crispino R, Mariniello M, Petruzzelli R, Ranucci G, Iorio R, Pietrocola F, Einer C, Borchard S, Zibert A, Schmidt HH, Di Schiavi E, Puchkova LV, Franco B, Kroemer G, Zischka H, Polishchuk RS.

Gastroenterology. 2019 Mar;156(4):1173-1189.e5. doi: 10.1053/j.gastro.2018.11.032. Epub 2018 Nov 17.


Copper Metabolism of Newborns Is Adapted to Milk Ceruloplasmin as a Nutritive Source of Copper: Overview of the Current Data.

Puchkova LV, Babich PS, Zatulovskaia YA, Ilyechova EY, Di Sole F.

Nutrients. 2018 Oct 30;10(11). pii: E1591. doi: 10.3390/nu10111591. Review.


A low blood copper concentration is a co-morbidity burden factor in Parkinson's disease development.

Ilyechova EY, Miliukhina IV, Orlov IA, Muruzheva ZM, Puchkova LV, Karpenko MN.

Neurosci Res. 2018 Oct;135:54-62. doi: 10.1016/j.neures.2017.11.011. Epub 2018 Jan 8.


The Extracellular Domain of Human High Affinity Copper Transporter (hNdCTR1), Synthesized by E. coli Cells, Chelates Silver and Copper Ions In Vivo.

Sankova TP, Orlov IA, Saveliev AN, Kirilenko DA, Babich PS, Brunkov PN, Puchkova LV.

Biomolecules. 2017 Nov 3;7(4). pii: E78. doi: 10.3390/biom7040078.


The role of subcutaneous adipose tissue in supporting the copper balance in rats with a chronic deficiency in holo-ceruloplasmin.

Ilyechova EY, Tsymbalenko NV, Puchkova LV.

PLoS One. 2017 Apr 5;12(4):e0175214. doi: 10.1371/journal.pone.0175214. eCollection 2017.


Biogenetic and morphofunctional heterogeneity of mitochondria: the case of synaptic mitochondria.

Fedorovich SV, Waseem TV, Puchkova LV.

Rev Neurosci. 2017 May 24;28(4):363-373. doi: 10.1515/revneuro-2016-0077. Review.


New silver nanoparticles induce apoptosis-like process in E. coli and interfere with mammalian copper metabolism.

Orlov IA, Sankova TP, Babich PS, Sosnin IM, Ilyechova EY, Kirilenko DA, Brunkov PN, Ataev GL, Romanov AE, Puchkova LV.

Int J Nanomedicine. 2016 Dec 15;11:6561-6574. doi: 10.2147/IJN.S117745. eCollection 2016.


In vivo effect of copper status on cisplatin-induced nephrotoxicity.

Puchkova LV, Skvortsov AN, Rusconi P, Ilyechova EY, Broggini M.

Biometals. 2016 Oct;29(5):841-9. doi: 10.1007/s10534-016-9955-z. Epub 2016 Aug 1.


The Features of Copper Metabolism in the Rat Liver during Development.

Zatulovskaia YA, Ilyechova EY, Puchkova LV.

PLoS One. 2015 Oct 16;10(10):e0140797. doi: 10.1371/journal.pone.0140797. eCollection 2015.


Non-hepatic tumors change the activity of genes encoding copper trafficking proteins in the liver.

Babich PS, Skvortsov AN, Rusconi P, Tsymbalenko NV, Mutanen M, Puchkova LV, Broggini M.

Cancer Biol Ther. 2013 Jul;14(7):614-24. doi: 10.4161/cbt.24594. Epub 2013 May 10.


Serum depletion of holo-ceruloplasmin induced by silver ions in vivo reduces uptake of cisplatin.

Zatulovskiy EA, Skvortsov AN, Rusconi P, Ilyechova EY, Babich PS, Tsymbalenko NV, Broggini M, Puchkova LV.

J Inorg Biochem. 2012 Nov;116:88-96. doi: 10.1016/j.jinorgbio.2012.07.003. Epub 2012 Jul 8.


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