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Causal Link between n-3 Polyunsaturated Fatty Acid Deficiency and Motivation Deficits.

Ducrocq F, Walle R, Contini A, Oummadi A, Caraballo B, van der Veldt S, Boyer ML, Aby F, Tolentino-Cortez T, Helbling JC, Martine L, Grégoire S, Cabaret S, Vancassel S, Layé S, Kang JX, Fioramonti X, Berdeaux O, Barreda-Gómez G, Masson E, Ferreira G, Ma DWL, Bosch-Bouju C, De Smedt-Peyrusse V, Trifilieff P.

Cell Metab. 2020 Mar 2. pii: S1550-4131(20)30071-1. doi: 10.1016/j.cmet.2020.02.012. [Epub ahead of print]


Age-Related Changes in the Gut Microbiota Modify Brain Lipid Composition.

Albouery M, Buteau B, Grégoire S, Cherbuy C, Pais de Barros JP, Martine L, Chain F, Cabaret S, Berdeaux O, Bron AM, Acar N, Langella P, Bringer MA.

Front Cell Infect Microbiol. 2020 Jan 14;9:444. doi: 10.3389/fcimb.2019.00444. eCollection 2019.


Is 24(S)-hydroxycholesterol a potent modulator of cholesterol metabolism in Müller cells? An in vitro study about neuron to glia communication in the retina.

Léger-Charnay E, Masson EAY, Morala T, Martine L, Buteau B, Leclere L, Bretillon L, Gambert S.

Exp Eye Res. 2019 Dec;189:107857. doi: 10.1016/j.exer.2019.107857. Epub 2019 Oct 22. No abstract available.


Profile of Fatty Acids, Tocopherols, Phytosterols and Polyphenols in Mediterranean Oils (Argan Oils, Olive Oils, Milk Thistle Seed Oils and Nigella Seed Oil) and Evaluation of their Antioxidant and Cytoprotective Activities.

Zarrouk A, Martine L, Grégoire S, Nury T, Meddeb W, Camus E, Badreddine A, Durand P, Namsi A, Yammine A, Nasser B, Mejri M, Bretillon L, Mackrill JJ, Cherkaoui-Malki M, Hammami M, Lizard G.

Curr Pharm Des. 2019;25(15):1791-1805. doi: 10.2174/1381612825666190705192902.


Benefits of dimension reduction in penalized regression methods for high-dimensional grouped data: a case study in low sample size.

Ajana S, Acar N, Bretillon L, Hejblum BP, Jacqmin-Gadda H, Delcourt C; BLISAR Study Group .

Bioinformatics. 2019 Oct 1;35(19):3628-3634. doi: 10.1093/bioinformatics/btz135.


Argan Oil-Mediated Attenuation of Organelle Dysfunction, Oxidative Stress and Cell Death Induced by 7-Ketocholesterol in Murine Oligodendrocytes 158N.

Badreddine A, Zarrouk A, Karym EM, Debbabi M, Nury T, Meddeb W, Sghaier R, Bezine M, Vejux A, Martine L, Grégoire S, Bretillon L, Prost-Camus E, Durand P, Prost M, Moreau T, Cherkaoui-Malki M, Nasser B, Lizard G.

Int J Mol Sci. 2017 Oct 23;18(10). pii: E2220. doi: 10.3390/ijms18102220.


Cholesterol metabolism and glaucoma: Modulation of Muller cell membrane organization by 24S-hydroxycholesterol.

Gambert S, Gabrielle PH, Masson E, Leger-Charnay E, Ferrerro A, Vannier A, Gendrault C, Lachot M, Creuzot-Garcher C, Bron A, Gregoire S, Leclere L, Martine L, Lucchi G, Truntzer C, Pecqueur D, Bretillon L.

Chem Phys Lipids. 2017 Oct;207(Pt B):179-191. doi: 10.1016/j.chemphyslip.2017.05.007. Epub 2017 Jun 4.


Ganglioside Profiling of the Human Retina: Comparison with Other Ocular Structures, Brain and Plasma Reveals Tissue Specificities.

Sibille E, Berdeaux O, Martine L, Bron AM, Creuzot-Garcher CP, He Z, Thuret G, Bretillon L, Masson EA.

PLoS One. 2016 Dec 20;11(12):e0168794. doi: 10.1371/journal.pone.0168794. eCollection 2016.


Protective Effects of α-Tocopherol, γ-Tocopherol and Oleic Acid, Three Compounds of Olive Oils, and No Effect of Trolox, on 7-Ketocholesterol-Induced Mitochondrial and Peroxisomal Dysfunction in Microglial BV-2 Cells.

Debbabi M, Nury T, Zarrouk A, Mekahli N, Bezine M, Sghaier R, Grégoire S, Martine L, Durand P, Camus E, Vejux A, Jabrane A, Bretillon L, Prost M, Moreau T, Ammou SB, Hammami M, Lizard G.

Int J Mol Sci. 2016 Nov 25;17(12). pii: E1973.


Diversity of Sterol Composition in Tunisian Pistacia lentiscus Seed Oil.

Mezni F, Labidi A, Khouja ML, Martine L, Berdeaux O, Khaldi A.

Chem Biodivers. 2016 May;13(5):544-8. doi: 10.1002/cbdv.201500160.


Plasmatic Ganglioside Profile and Age-Related Macular Degeneration: A Case-Control Study.

Dossarps D, Martine L, Berdeaux O, Sibille E, Bron AM, Creuzot-Garcher CP, Bretillon L, Masson EA.

Ophthalmic Res. 2016;56(1):41-8. doi: 10.1159/000444059. Epub 2016 Apr 2.


Apprehending ganglioside diversity: a comprehensive methodological approach.

Masson EA, Sibille E, Martine L, Chaux-Picquet F, Bretillon L, Berdeaux O.

J Lipid Res. 2015 Sep;56(9):1821-35. doi: 10.1194/jlr.D060764. Epub 2015 Jul 4.


Analysis of pecan nut (Carya illinoinensis) unsaponifiable fraction. Effect of ripening stage on phytosterols and phytostanols composition.

Bouali I, Trabelsi H, Herchi W, Martine L, Albouchi A, Bouzaien G, Sifi S, Boukhchina S, Berdeaux O.

Food Chem. 2014 Dec 1;164:309-16. doi: 10.1016/j.foodchem.2014.05.029. Epub 2014 May 16.


In vivo consequences of cholesterol-24S-hydroxylase (CYP46A1) inhibition by voriconazole on cholesterol homeostasis and function in the rat retina.

Fourgeux C, Martine L, Acar N, Bron AM, Creuzot-Garcher CP, Bretillon L.

Biochem Biophys Res Commun. 2014 Apr 11;446(3):775-81. doi: 10.1016/j.bbrc.2014.01.118. Epub 2014 Feb 1.


Steady-state levels of retinal 24S-hydroxycholesterol are maintained by glial cells intervention after elevation of intraocular pressure in the rat.

Fourgeux C, Martine L, Pasquis B, Maire MA, Acar N, Creuzot-Garcher C, Bron A, Bretillon L.

Acta Ophthalmol. 2012 Nov;90(7):e560-7. doi: 10.1111/j.1755-3768.2012.02490.x. Epub 2012 Sep 23.


Lipid composition of the human eye: are red blood cells a good mirror of retinal and optic nerve fatty acids?

Acar N, Berdeaux O, Grégoire S, Cabaret S, Martine L, Gain P, Thuret G, Creuzot-Garcher CP, Bron AM, Bretillon L.

PLoS One. 2012;7(4):e35102. doi: 10.1371/journal.pone.0035102. Epub 2012 Apr 9.


Absence of oxysterol-like side effects in human monocytic cells treated with phytosterols and oxyphytosterols.

Vejux A, Montange T, Martine L, Zarrouk A, Riedinger JM, Lizard G.

J Agric Food Chem. 2012 Apr 25;60(16):4060-6. doi: 10.1021/jf300487r. Epub 2012 Apr 16.


Identification and quantification of phosphatidylcholines containing very-long-chain polyunsaturated fatty acid in bovine and human retina using liquid chromatography/tandem mass spectrometry.

Berdeaux O, Juaneda P, Martine L, Cabaret S, Bretillon L, Acar N.

J Chromatogr A. 2010 Dec 3;1217(49):7738-48. doi: 10.1016/j.chroma.2010.10.039. Epub 2010 Oct 14.


Primary open-angle glaucoma: association with cholesterol 24S-hydroxylase (CYP46A1) gene polymorphism and plasma 24-hydroxycholesterol levels.

Fourgeux C, Martine L, Björkhem I, Diczfalusy U, Joffre C, Acar N, Creuzot-Garcher C, Bron A, Bretillon L.

Invest Ophthalmol Vis Sci. 2009 Dec;50(12):5712-7. doi: 10.1167/iovs.09-3655. Epub 2009 Jun 24.


ApoB100,LDLR-/- mice exhibit reduced electroretinographic response and cholesteryl esters deposits in the retina.

Bretillon L, Acar N, Seeliger MW, Santos M, Maire MA, Juanéda P, Martine L, Grégoire S, Joffre C, Bron AM, Creuzot-Garcher C.

Invest Ophthalmol Vis Sci. 2008 Apr;49(4):1307-14. doi: 10.1167/iovs.07-0808.


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