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Items: 14


Deletion of the Sm1 encoding motif in the lsm gene results in distinct changes in the transcriptome and enhanced swarming activity of Haloferax cells.

Maier LK, Benz J, Fischer S, Alstetter M, Jaschinski K, Hilker R, Becker A, Allers T, Soppa J, Marchfelder A.

Biochimie. 2015 Oct;117:129-37. doi: 10.1016/j.biochi.2015.02.023.


The Adaptive Immune System of Haloferax volcanii.

Maier LK, Dyall-Smith M, Marchfelder A.

Life (Basel). 2015 Feb 16;5(1):521-37. doi: 10.3390/life5010521. Review.


An active immune defense with a minimal CRISPR (clustered regularly interspaced short palindromic repeats) RNA and without the Cas6 protein.

Maier LK, Stachler AE, Saunders SJ, Backofen R, Marchfelder A.

J Biol Chem. 2015 Feb 13;290(7):4192-201. doi: 10.1074/jbc.M114.617506.


Structural analyses of the CRISPR protein Csc2 reveal the RNA-binding interface of the type I-D Cas7 family.

Hrle A, Maier LK, Sharma K, Ebert J, Basquin C, Urlaub H, Marchfelder A, Conti E.

RNA Biol. 2014;11(8):1072-82. doi: 10.4161/rna.29893.


Small regulatory RNAs in Archaea.

Babski J, Maier LK, Heyer R, Jaschinski K, Prasse D, Jäger D, Randau L, Schmitz RA, Marchfelder A, Soppa J.

RNA Biol. 2014;11(5):484-93. Review.


A complex of Cas proteins 5, 6, and 7 is required for the biogenesis and stability of clustered regularly interspaced short palindromic repeats (crispr)-derived rnas (crrnas) in Haloferax volcanii.

Brendel J, Stoll B, Lange SJ, Sharma K, Lenz C, Stachler AE, Maier LK, Richter H, Nickel L, Schmitz RA, Randau L, Allers T, Urlaub H, Backofen R, Marchfelder A.

J Biol Chem. 2014 Mar 7;289(10):7164-77. doi: 10.1074/jbc.M113.508184.


Requirements for a successful defence reaction by the CRISPR-Cas subtype I-B system.

Stoll B, Maier LK, Lange SJ, Brendel J, Fischer S, Backofen R, Marchfelder A.

Biochem Soc Trans. 2013 Dec;41(6):1444-8. doi: 10.1042/BST20130098. Review.


Essential requirements for the detection and degradation of invaders by the Haloferax volcanii CRISPR/Cas system I-B.

Maier LK, Lange SJ, Stoll B, Haas KA, Fischer S, Fischer E, Duchardt-Ferner E, Wöhnert J, Backofen R, Marchfelder A.

RNA Biol. 2013 May;10(5):865-74. doi: 10.4161/rna.24282.


The immune system of halophilic archaea.

Maier LK, Fischer S, Stoll B, Brendel J, Pfeiffer F, Dyall-Smith M, Marchfelder A.

Mob Genet Elements. 2012 Sep 1;2(5):228-232.


The ring of confidence: a haloarchaeal CRISPR/Cas system.

Maier LK, Stoll B, Brendel J, Fischer S, Pfeiffer F, Dyall-Smith M, Marchfelder A.

Biochem Soc Trans. 2013 Feb 1;41(1):374-8. doi: 10.1042/BST20120263.


An archaeal immune system can detect multiple protospacer adjacent motifs (PAMs) to target invader DNA.

Fischer S, Maier LK, Stoll B, Brendel J, Fischer E, Pfeiffer F, Dyall-Smith M, Marchfelder A.

J Biol Chem. 2012 Sep 28;287(40):33351-63.


Small RNAs for defence and regulation in archaea.

Marchfelder A, Fischer S, Brendel J, Stoll B, Maier LK, Jäger D, Prasse D, Plagens A, Schmitz RA, Randau L.

Extremophiles. 2012 Sep;16(5):685-96. doi: 10.1007/s00792-012-0469-5. Review.


Regulatory RNAs in Haloferax volcanii.

Fischer S, Benz J, Späth B, Jellen-Ritter A, Heyer R, Dörr M, Maier LK, Menzel-Hobeck C, Lehr M, Jantzer K, Babski J, Soppa J, Marchfelder A.

Biochem Soc Trans. 2011 Jan;39(1):159-62. doi: 10.1042/BST0390159.


The archaeal Lsm protein binds to small RNAs.

Fischer S, Benz J, Späth B, Maier LK, Straub J, Granzow M, Raabe M, Urlaub H, Hoffmann J, Brutschy B, Allers T, Soppa J, Marchfelder A.

J Biol Chem. 2010 Nov 5;285(45):34429-38. doi: 10.1074/jbc.M110.118950.

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