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Items: 1 to 20 of 54


Syntheses of Benzo[d]Thiazol-2(3H)-One Derivatives and Their Antidepressant and Anticonvulsant Effects.

Jin Q, Fu Z, Guan L, Jiang H.

Mar Drugs. 2019 Jul 23;17(7). pii: E430. doi: 10.3390/md17070430.


Genomic analyses of an extensive collection of wild and cultivated accessions provide new insights into peach breeding history.

Li Y, Cao K, Zhu G, Fang W, Chen C, Wang X, Zhao P, Guo J, Ding T, Guan L, Zhang Q, Guo W, Fei Z, Wang L.

Genome Biol. 2019 Feb 21;20(1):36. doi: 10.1186/s13059-019-1648-9.


Antigen-specific CD8+ memory stem T cells generated from human peripheral blood effectively eradicate allogeneic targets in mice.

Guan L, Li X, Wei J, Liang Z, Yang J, Weng X, Wu X.

Stem Cell Res Ther. 2018 Dec 7;9(1):337. doi: 10.1186/s13287-018-1080-1.


Further evidence for "gain-of-function" mechanism of DFNA5 related hearing loss.

Wang H, Guan J, Guan L, Yang J, Wu K, Lin Q, Xiong W, Lan L, Zhao C, Xie L, Yu L, Dan Bing, Zhao L, Wang D, Wang Q.

Sci Rep. 2018 May 30;8(1):8424. doi: 10.1038/s41598-018-26554-7.


Comparative Transcriptome and Microscopy Analyses Provide Insights into Flat Shape Formation in Peach (Prunus persica).

Guo J, Cao K, Li Y, Yao JL, Deng C, Wang Q, Zhu G, Fang W, Chen C, Wang X, Guan L, Ding T, Wang L.

Front Plant Sci. 2018 Jan 4;8:2215. doi: 10.3389/fpls.2017.02215. eCollection 2017.


Revealing Alzheimer's disease genes spectrum in the whole-genome by machine learning.

Huang X, Liu H, Li X, Guan L, Li J, Tellier LCAM, Yang H, Wang J, Zhang J.

BMC Neurol. 2018 Jan 10;18(1):5. doi: 10.1186/s12883-017-1010-3.


A trehalose biosynthetic enzyme doubles as an osmotic stress sensor to regulate bacterial morphogenesis.

Chen X, An L, Fan X, Ju F, Zhang B, Sun H, Xiao J, Hu W, Qu T, Guan L, Tang S, Chen T, Liu G, Dyson P.

PLoS Genet. 2017 Oct 30;13(10):e1007062. doi: 10.1371/journal.pgen.1007062. eCollection 2017 Oct.


Identification of a missense HOXD13 mutation in a Chinese family with syndactyly type I-c using exome sequencing.

Deng H, Tan T, He Q, Lin Q, Yang Z, Zhu A, Guan L, Xiao J, Song Z, Guo Y.

Mol Med Rep. 2017 Jul;16(1):473-477. doi: 10.3892/mmr.2017.6576. Epub 2017 May 11.


Compound heterozygous POMT1 mutations in a Chinese family with autosomal recessive muscular dystrophy-dystroglycanopathy C1.

Hu P, Wu S, Yuan L, Lin Q, Zheng W, Xia H, Xu H, Guan L, Deng H.

J Cell Mol Med. 2017 Jul;21(7):1388-1393. doi: 10.1111/jcmm.13068. Epub 2017 Feb 3.


Identification of a novel collagen type IV alpha-4 (COL4A4) mutation in a Chinese family with autosomal dominant Alport syndrome using exome sequencing.

Deng S, Xu H, Yuan J, Xiao J, Yuan L, Deng X, Guan L, Zhu A, Rong P, Zhang J, Deng H.

Indian J Med Res. 2016 Aug;144(2):200-205. doi: 10.4103/0971-5916.195026.


A comparison of bone mineral densities and body composition between Southeast Asia college students and Chinese college students.

Liu P, Ye Z, Lu J, Lu H, Guan L, Teng Z, Gao S, Li M.

Medicine (Baltimore). 2016 Sep;95(37):e4724. doi: 10.1097/MD.0000000000004724.


Structural Features and Potent Antidepressant Effects of Total Sterols and β-sitosterol Extracted from Sargassum horneri.

Zhao D, Zheng L, Qi L, Wang S, Guan L, Xia Y, Cai J.

Mar Drugs. 2016 Jun 28;14(7). pii: E123. doi: 10.3390/md14070123.


Exome Sequencing of a Pedigree Reveals S339L Mutation in the TLN2 Gene as a Cause of Fifth Finger Camptodactyly.

Deng H, Deng S, Xu H, Deng HX, Chen Y, Yuan L, Deng X, Yang S, Guan L, Zhang J, Yuan H, Guo Y.

PLoS One. 2016 May 25;11(5):e0155180. doi: 10.1371/journal.pone.0155180. eCollection 2016.


Identification of a Novel Missense FBN2 Mutation in a Chinese Family with Congenital Contractural Arachnodactyly Using Exome Sequencing.

Deng H, Lu Q, Xu H, Deng X, Yuan L, Yang Z, Guo Y, Lin Q, Xiao J, Guan L, Song Z.

PLoS One. 2016 May 19;11(5):e0155908. doi: 10.1371/journal.pone.0155908. eCollection 2016.


NRPB3, the third largest subunit of RNA polymerase II, is essential for stomatal patterning and differentiation in Arabidopsis.

Chen L, Guan L, Qian P, Xu F, Wu Z, Wu Y, He K, Gou X, Li J, Hou S.

Development. 2016 May 1;143(9):1600-11. doi: 10.1242/dev.129098. Epub 2016 Mar 17.


Identification of MFRP Mutations in Chinese Families with High Hyperopia.

Xu Y, Guan L, Xiao X, Zhang J, Li S, Jiang H, Jia X, Yin Y, Guo X, Yang Z, Zhang Q.

Optom Vis Sci. 2016 Jan;93(1):19-26. doi: 10.1097/OPX.0000000000000751.


Synthesis, potential anticonvulsant and antidepressant effects of 2-(5-methyl-2,3-dioxoindolin-1-yl)acetamide derivatives.

Zhen X, Peng Z, Zhao S, Han Y, Jin Q, Guan L.

Acta Pharm Sin B. 2015 Jul;5(4):343-9. doi: 10.1016/j.apsb.2015.01.008. Epub 2015 Mar 18.


Exome sequencing reveals mutation in GJA1 as a cause of keratoderma-hypotrichosis-leukonychia totalis syndrome.

Wang H, Cao X, Lin Z, Lee M, Jia X, Ren Y, Dai L, Guan L, Zhang J, Lin X, Zhang J, Chen Q, Feng C, Yihui Zhou E, Yin J, Xu G, Yang Y.

Hum Mol Genet. 2015 Nov 15;24(22):6564. doi: 10.1093/hmg/ddv365. Epub 2015 Sep 14. No abstract available.


Application of Whole Exome Sequencing in Six Families with an Initial Diagnosis of Autosomal Dominant Retinitis Pigmentosa: Lessons Learned.

Almoguera B, Li J, Fernandez-San Jose P, Liu Y, March M, Pellegrino R, Golhar R, Corton M, Blanco-Kelly F, López-Molina MI, García-Sandoval B, Guo Y, Tian L, Liu X, Guan L, Zhang J, Keating B, Xu X, Hakonarson H, Ayuso C.

PLoS One. 2015 Jul 21;10(7):e0133624. doi: 10.1371/journal.pone.0133624. eCollection 2015.


Characteristics of human umbilical cord mesenchymal stem cells during ex vivo expansion.

Li S, Wang Y, Guan L, Ji M.

Mol Med Rep. 2015 Sep;12(3):4320-4325. doi: 10.3892/mmr.2015.3999. Epub 2015 Jun 25.


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