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Items: 1 to 20 of 33

1.

Development of new methodologies for the chromogenic estimation of betrixaban concentrations in plasma.

Siriez R, Evrard J, Dogné JM, Pochet L, Bouvy C, Lessire S, Mullier F, Douxfils J.

Int J Lab Hematol. 2019 Apr;41(2):250-261. doi: 10.1111/ijlh.12963. Epub 2019 Jan 3.

PMID:
30604921
2.

1-(2-Hydroxybenzoyl)-thiosemicarbazides are promising antimicrobial agents targeting d-alanine-d-alanine ligase in bacterio.

Ameryckx A, Thabault L, Pochet L, Leimanis S, Poupaert JH, Wouters J, Joris B, Van Bambeke F, Frédérick R.

Eur J Med Chem. 2018 Nov 5;159:324-338. doi: 10.1016/j.ejmech.2018.09.067. Epub 2018 Sep 28.

PMID:
30300845
3.

Development and validation of a liquid chromatography/tandem mass spectrometry method for the simultaneous quantification of serotonin and thromboxane B2 from activated platelets.

Minet V, Evrard J, Vancraeynest C, Dogné JM, Mullier F, Pochet L.

Int J Lab Hematol. 2018 Dec;40(6):663-671. doi: 10.1111/ijlh.12901. Epub 2018 Jul 17.

PMID:
30019376
4.

Effect of ABCB1 genetic polymorphisms on the transport of rivaroxaban in HEK293 recombinant cell lines.

Sennesael AL, Panin N, Vancraeynest C, Pochet L, Spinewine A, Haufroid V, Elens L.

Sci Rep. 2018 Jul 12;8(1):10514. doi: 10.1038/s41598-018-28622-4.

5.

Betrixaban: Impact on Routine and Specific Coagulation Assays-A Practical Laboratory Guide.

Siriez R, Evrard J, Dogné JM, Pochet L, Gheldof D, Chatelain B, Mullier F, Douxfils J.

Thromb Haemost. 2018 Jul;118(7):1203-1214. doi: 10.1055/s-0038-1657772. Epub 2018 Jun 11.

PMID:
29890519
6.

Enhancing Action of Positive Allosteric Modulators through the Design of Dimeric Compounds.

Drapier T, Geubelle P, Bouckaert C, Nielsen L, Laulumaa S, Goffin E, Dilly S, Francotte P, Hanson J, Pochet L, Kastrup JS, Pirotte B.

J Med Chem. 2018 Jun 28;61(12):5279-5291. doi: 10.1021/acs.jmedchem.8b00250. Epub 2018 Jun 8.

PMID:
29775064
7.

31ièmes Journées Franco-Belges de Pharmacochimie: Meeting Report.

Frédérick R, Pochet L, De Tullio P, Dufrasne F.

Pharmaceuticals (Basel). 2017 Dec 4;10(4). pii: E94. doi: 10.3390/ph10040094.

8.

Discovery and assessment of water soluble coumarins as inhibitors of the coagulation contact pathway.

Bouckaert C, Zhu S, Govers-Riemslag JWP, Depoorter M, Diamond SL, Pochet L.

Thromb Res. 2017 Sep;157:126-133. doi: 10.1016/j.thromres.2017.07.015. Epub 2017 Jul 19.

PMID:
28738274
9.

An optimized dRVVT-based assay to estimate the intensity of anticoagulation in patients treated with direct oral anticoagulants.

Sennesael AL, Exner T, Chatelain B, Lessire S, Larock AS, Vancraeynest C, Pochet L, Dogné JM, Spinewine A, Mullier F, Douxfils J.

Thromb Res. 2017 Sep;157:29-37. doi: 10.1016/j.thromres.2017.06.034. Epub 2017 Jun 28.

PMID:
28686914
10.

Capillary electrophoresis in the context of drug discovery.

Farcaş E, Pochet L, Crommen J, Servais AC, Fillet M.

J Pharm Biomed Anal. 2017 Sep 10;144:195-212. doi: 10.1016/j.jpba.2017.02.022. Epub 2017 Feb 21. Review.

PMID:
28242155
11.

Estimation of Rivaroxaban Plasma Concentrations in the Perioperative Setting in Patients With or Without Heparin Bridging.

Lessire S, Douxfils J, Pochet L, Dincq AS, Larock AS, Gourdin M, Dogné JM, Chatelain B, Mullier F.

Clin Appl Thromb Hemost. 2018 Jan;24(1):129-138. doi: 10.1177/1076029616675968. Epub 2016 Nov 3.

12.

Synthesis, evaluation and structure-activity relationship of new 3-carboxamide coumarins as FXIIa inhibitors.

Bouckaert C, Serra S, Rondelet G, Dolušić E, Wouters J, Dogné JM, Frédérick R, Pochet L.

Eur J Med Chem. 2016 Mar 3;110:181-94. doi: 10.1016/j.ejmech.2016.01.023. Epub 2016 Jan 16.

PMID:
26827162
13.

Fully automated electrophoretically mediated microanalysis for CYP1A1 activity monitoring optimized by multivariate approach.

Farcaş E, Servais AC, Lamalle C, Chiap P, Pochet L, Fillet M.

Electrophoresis. 2016 Jan;37(2):248-55. doi: 10.1002/elps.201500214. Epub 2015 Nov 25.

PMID:
26462449
14.

Correction to Deciphering the Mechanism of Carbonic Anhydrase Inhibition with Coumarins and Thiocoumarins.

Maresca A, Temperini C, Pochet L, Masereel B, Scozzafava A, Supuran CT.

J Med Chem. 2015 Jul 23;58(14):5689. doi: 10.1021/acs.jmedchem.5b00969. Epub 2015 Jun 30. No abstract available.

PMID:
26125495
15.

3D-QSAR, design, synthesis and characterization of trisubstituted harmine derivatives with in vitro antiproliferative properties.

Meinguet C, Bruyère C, Frédérick R, Mathieu V, Vancraeynest C, Pochet L, Laloy J, Mortier J, Wolber G, Kiss R, Masereel B, Wouters J.

Eur J Med Chem. 2015 Apr 13;94:45-55. doi: 10.1016/j.ejmech.2015.02.044. Epub 2015 Feb 24.

16.

Thiosemicarbazide, a fragment with promising indolamine-2,3-dioxygenase (IDO) inhibition properties.

Serra S, Moineaux L, Vancraeynest C, Masereel B, Wouters J, Pochet L, Frédérick R.

Eur J Med Chem. 2014 Jul 23;82:96-105. doi: 10.1016/j.ejmech.2014.05.044. Epub 2014 May 15.

PMID:
24878638
17.

Determination of inhibitory potency of argatroban toward thrombin by electrophoretically mediated microanalysis.

Pochet L, Servais AC, Farcas E, Bettonville V, Bouckaert C, Fillet M.

Talanta. 2013 Nov 15;116:719-25. doi: 10.1016/j.talanta.2013.07.030. Epub 2013 Jul 31.

PMID:
24148466
18.

Novel trisubstituted harmine derivatives with original in vitro anticancer activity.

Frédérick R, Bruyère C, Vancraeynest C, Reniers J, Meinguet C, Pochet L, Backlund A, Masereel B, Kiss R, Wouters J.

J Med Chem. 2012 Jul 26;55(14):6489-501. doi: 10.1021/jm300542e. Epub 2012 Jul 18.

PMID:
22770529
19.

Tryptophan 2,3-dioxygenase (TDO) inhibitors. 3-(2-(pyridyl)ethenyl)indoles as potential anticancer immunomodulators.

Dolusić E, Larrieu P, Moineaux L, Stroobant V, Pilotte L, Colau D, Pochet L, Van den Eynde B, Masereel B, Wouters J, Frédérick R.

J Med Chem. 2011 Aug 11;54(15):5320-34. doi: 10.1021/jm2006782. Epub 2011 Jul 18.

PMID:
21726069
20.

Online magnetic bead based dynamic protein affinity selection coupled to LC-MS for the screening of acetylcholine binding protein ligands.

Pochet L, Heus F, Jonker N, Lingeman H, Smit AB, Niessen WM, Kool J.

J Chromatogr B Analyt Technol Biomed Life Sci. 2011 Jun 15;879(20):1781-8. doi: 10.1016/j.jchromb.2011.04.023. Epub 2011 Apr 28.

PMID:
21565564

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