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Items: 1 to 20 of 52


Targeting the CD40-CD154 Signaling Pathway for Treatment of Autoimmune Arthritis.

Lai JH, Luo SF, Ho LJ.

Cells. 2019 Aug 18;8(8). pii: E927. doi: 10.3390/cells8080927. Review.


Anti-inflammatory and anti-osteoarthritis effects of Cm-02 and Ck-02.

Ho YJ, Lu JW, Ho LJ, Lai JH, Huang HS, Lee CC, Lin TY, Lien SB, Lin LC, Chen LW, Gong Z, Shen MC, Liu FC.

Biochem Biophys Res Commun. 2019 Sep 10;517(1):155-163. doi: 10.1016/j.bbrc.2019.07.036. Epub 2019 Jul 25.


Pitavastatin Exerts Potent Anti-Inflammatory and Immunomodulatory Effects via the Suppression of AP-1 Signal Transduction in Human T Cells.

Chen LW, Lin CS, Tsai MC, Shih SF, Lim ZW, Chen SJ, Tsui PF, Ho LJ, Lai JH, Liou JT.

Int J Mol Sci. 2019 Jul 19;20(14). pii: E3534. doi: 10.3390/ijms20143534.


Compound K inhibits priming and mitochondria-associated activating signals of NLRP3 inflammasome in renal tubulointerstitial lesions.

Hsu WH, Hua KF, Tuan LH, Tsai YL, Chu LJ, Lee YC, Wong WT, Lee SL, Lai JH, Chu CL, Ho LJ, Chiu HW, Hsu YJ, Chen CH, Ka SM, Chen A.

Nephrol Dial Transplant. 2019 May 7. pii: gfz073. doi: 10.1093/ndt/gfz073. [Epub ahead of print]


Useful message in choosing optimal biological agents for patients with autoimmune arthritis.

Lai JH, Ling XC, Ho LJ.

Biochem Pharmacol. 2019 Jul;165:99-111. doi: 10.1016/j.bcp.2019.03.007. Epub 2019 Mar 13. Review.


Spices and Atherosclerosis.

Tsui PF, Lin CS, Ho LJ, Lai JH.

Nutrients. 2018 Nov 10;10(11). pii: E1724. doi: 10.3390/nu10111724. Review.


Operation of mitochondrial machinery in viral infection-induced immune responses.

Lai JH, Luo SF, Ho LJ.

Biochem Pharmacol. 2018 Oct;156:348-356. doi: 10.1016/j.bcp.2018.08.044. Epub 2018 Aug 31. Review.


Infection with the dengue RNA virus activates TLR9 signaling in human dendritic cells.

Lai JH, Wang MY, Huang CY, Wu CH, Hung LF, Yang CY, Ke PY, Luo SF, Liu SJ, Ho LJ.

EMBO Rep. 2018 Aug;19(8). pii: e46182. doi: 10.15252/embr.201846182. Epub 2018 Jun 7.


Arthroprotective Effects of Cf-02 Sharing Structural Similarity with Quercetin.

Liu FC, Lu JW, Chien CY, Huang HS, Lee CC, Lien SB, Lin LC, Chen LW, Ho YJ, Shen MC, Ho LJ, Lai JH.

Int J Mol Sci. 2018 May 14;19(5). pii: E1453. doi: 10.3390/ijms19051453.


Monosodium urate crystals induced ICAM-1 expression and cell-cell adhesion in renal mesangial cells: Implications for the pathogenesis of gouty nephropathy.

Luo SF, Chin CY, Ho LJ, Tseng WY, Kuo CF, Lai JH.

J Microbiol Immunol Infect. 2018 Jan 31. pii: S1684-1182(18)30003-3. doi: 10.1016/j.jmii.2017.12.004. [Epub ahead of print]


Chondroprotective Effects and Mechanisms of Dextromethorphan: Repurposing Antitussive Medication for Osteoarthritis Treatment.

Chen LW, Liu FC, Hung LF, Huang CY, Lien SB, Lin LC, Lai JH, Ho LJ.

Int J Mol Sci. 2018 Mar 12;19(3). pii: E825. doi: 10.3390/ijms19030825.


Translational Implication of Galectin-9 in the Pathogenesis and Treatment of Viral Infection.

Lai JH, Luo SF, Wang MY, Ho LJ.

Int J Mol Sci. 2017 Oct 8;18(10). pii: E2108. doi: 10.3390/ijms18102108. Review.


JNK/AP-1 activation contributes to tetrandrine resistance in T-cell acute lymphoblastic leukaemia.

Liou JT, Lin CS, Liao YC, Ho LJ, Yang SP, Lai JH.

Acta Pharmacol Sin. 2017 Aug;38(8):1171-1183. doi: 10.1038/aps.2017.26. Epub 2017 Jun 12.


Physiological concentrations of soluble uric acid are chondroprotective and anti-inflammatory.

Lai JH, Luo SF, Hung LF, Huang CY, Lien SB, Lin LC, Liu FC, Yen BL, Ho LJ.

Sci Rep. 2017 May 24;7(1):2359. doi: 10.1038/s41598-017-02640-0.


Epigallocatechin-3-gallate Reduces Scavenger Receptor A Expression and Foam Cell Formation in Human Macrophages.

Chen SJ, Kao YH, Jing L, Chuang YP, Wu WL, Liu ST, Huang SM, Lai JH, Ho LJ, Tsai MC, Lin CS.

J Agric Food Chem. 2017 Apr 19;65(15):3141-3150. doi: 10.1021/acs.jafc.6b05832. Epub 2017 Apr 10.


Gentiana scabra Reduces SR-A Expression and Oxidized-LDL Uptake in Human Macrophages.

Lin CS, Liu PY, Lian CH, Lin CH, Lai JH, Ho LJ, Yang SP, Cheng SM.

Acta Cardiol Sin. 2016 Jul;32(4):460-6.


Dengue virus infection induces interferon-lambda1 to facilitate cell migration.

Hsu YL, Wang MY, Ho LJ, Lai JH.

Sci Rep. 2016 Jul 26;6:24530. doi: 10.1038/srep24530.


A New Application of Parallel Synthesis Strategy for Discovery of Amide-Linked Small Molecules as Potent Chondroprotective Agents in TNF-α-Stimulated Chondrocytes.

Lee CC, Lo Y, Ho LJ, Lai JH, Lien SB, Lin LC, Chen CL, Chen TC, Liu FC, Huang HS.

PLoS One. 2016 Mar 10;11(3):e0149317. doi: 10.1371/journal.pone.0149317. eCollection 2016. Erratum in: PLoS One. 2016;11(4):e0154067.


Biological effects of interleukin-6: Clinical applications in autoimmune diseases and cancers.

Ho LJ, Luo SF, Lai JH.

Biochem Pharmacol. 2015 Sep 1;97(1):16-26. doi: 10.1016/j.bcp.2015.06.009. Epub 2015 Jun 12. Review.


Up-regulation of galectin-9 induces cell migration in human dendritic cells infected with dengue virus.

Hsu YL, Wang MY, Ho LJ, Huang CY, Lai JH.

J Cell Mol Med. 2015 May;19(5):1065-76. doi: 10.1111/jcmm.12500. Epub 2015 Mar 6.

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