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Items: 1 to 20 of 37


Neoplastic Transformation of Human Mesenchymal Stromal Cells Mediated via LIN28B.

Vishnubalaji R, Elango R, Al-Toub M, Manikandan M, Al-Rikabi A, Harkness L, Ditzel N, Atteya M, Hamam R, Alfayez M, Aldahmash A, Kassem M, Alajez NM.

Sci Rep. 2019 May 30;9(1):8101. doi: 10.1038/s41598-019-44536-1.


Fibronectin-conjugated thermoresponsive nanobridges generate three dimensional human pluripotent stem cell cultures for differentiation towards the neural lineages.

Harkness L, Chen X, Jia Z, Davies AM, Monteiro M, Gray P, Pera M.

Stem Cell Res. 2019 Jul;38:101441. doi: 10.1016/j.scr.2019.101441. Epub 2019 Apr 23.


Media composition modulates human embryonic stem cell morphology and may influence preferential lineage differentiation potential.

Harkness L, Chen X, Gillard M, Gray PP, Davies AM.

PLoS One. 2019 Mar 19;14(3):e0213678. doi: 10.1371/journal.pone.0213678. eCollection 2019.


TAFA2 Induces Skeletal (Stromal) Stem Cell Migration Through Activation of Rac1-p38 Signaling.

Jafari A, Isa A, Chen L, Ditzel N, Zaher W, Harkness L, Johnsen HE, Abdallah BM, Clausen C, Kassem M.

Stem Cells. 2019 Mar;37(3):407-416. doi: 10.1002/stem.2955. Epub 2018 Dec 17.


Molecular Phenotyping of Telomerized Human Bone Marrow Skeletal Stem Cells Reveals a Genetic Program of Enhanced Proliferation and Maintenance of Differentiation Responses.

Twine NA, Harkness L, Adjaye J, Aldahmash A, Wilkins MR, Kassem M.

JBMR Plus. 2018 May 24;2(5):257-267. doi: 10.1002/jbm4.10050. eCollection 2018 Sep.


Induction of quiescence (G0) in bone marrow stromal stem cells enhances their stem cell characteristics.

Rumman M, Majumder A, Harkness L, Venugopal B, Vinay MB, Pillai MS, Kassem M, Dhawan J.

Stem Cell Res. 2018 Jul;30:69-80. doi: 10.1016/j.scr.2018.05.010. Epub 2018 May 17.


Methods for Expansion of Three-Dimensional Cultures of Human Embryonic Stem Cells Using a Thermoresponsive Polymer.

Chen X, Harkness L, Jia Z, Prowse A, Monteiro MJ, Gray PP.

Tissue Eng Part C Methods. 2018 Mar;24(3):146-157. doi: 10.1089/ten.TEC.2017.0331. Epub 2018 Feb 1.


Chromosome copy number variation in telomerized human bone marrow stromal cells; insights for monitoring safe ex-vivo expansion of adult stem cells.

Burns JS, Harkness L, Aldahmash A, Gautier L, Kassem M.

Stem Cell Res. 2017 Dec;25:6-17. doi: 10.1016/j.scr.2017.09.006. Epub 2017 Sep 25.


Bioactive nano-fibrous scaffold for vascularized craniofacial bone regeneration.

Prabha RD, Kraft DCE, Harkness L, Melsen B, Varma H, Nair PD, Kjems J, Kassem M.

J Tissue Eng Regen Med. 2018 Mar;12(3):e1537-e1548. doi: 10.1002/term.2579. Epub 2017 Dec 4.


Transcription factor ZNF25 is associated with osteoblast differentiation of human skeletal stem cells.

Twine NA, Harkness L, Kassem M, Wilkins MR.

BMC Genomics. 2016 Nov 4;17(1):872.


CD146/MCAM defines functionality of human bone marrow stromal stem cell populations.

Harkness L, Zaher W, Ditzel N, Isa A, Kassem M.

Stem Cell Res Ther. 2016 Jan 11;7:4. doi: 10.1186/s13287-015-0266-z.


Molecular characterisation of stromal populations derived from human embryonic stem cells: Similarities to immortalised bone marrow derived stromal stem cells.

Harkness L, Twine NA, Abu Dawud R, Jafari A, Aldahmash A, Wilkins MR, Adjaye J, Kassem M.

Bone Rep. 2015 Aug 4;3:32-39. doi: 10.1016/j.bonr.2015.07.002. eCollection 2015 Dec.


Proteomic Validation of Transcript Isoforms, Including Those Assembled from RNA-Seq Data.

Tay AP, Pang CN, Twine NA, Hart-Smith G, Harkness L, Kassem M, Wilkins MR.

J Proteome Res. 2015 Sep 4;14(9):3541-54. doi: 10.1021/pr5011394. Epub 2015 May 20.


An update of human mesenchymal stem cell biology and their clinical uses.

Zaher W, Harkness L, Jafari A, Kassem M.

Arch Toxicol. 2014 May;88(5):1069-82. doi: 10.1007/s00204-014-1232-8. Epub 2014 Apr 2. Review.


Tools to covisualize and coanalyze proteomic data with genomes and transcriptomes: validation of genes and alternative mRNA splicing.

Pang CN, Tay AP, Aya C, Twine NA, Harkness L, Hart-Smith G, Chia SZ, Chen Z, Deshpande NP, Kaakoush NO, Mitchell HM, Kassem M, Wilkins MR.

J Proteome Res. 2014 Jan 3;13(1):84-98. doi: 10.1021/pr400820p. Epub 2013 Nov 12.


Separate developmental programs for HLA-A and -B cell surface expression during differentiation from embryonic stem cells to lymphocytes, adipocytes and osteoblasts.

Sabir HJ, Nehlin JO, Qanie D, Harkness L, Prokhorova TA, Blagoev B, Kassem M, Isa A, Barington T.

PLoS One. 2013;8(1):e54366. doi: 10.1371/journal.pone.0054366. Epub 2013 Jan 18.


Derivation of stromal (skeletal and mesenchymal) stem-like cells from human embryonic stem cells.

Mahmood A, Harkness L, Abdallah BM, Elsafadi M, Al-Nbaheen MS, Aldahmash A, Kassem M.

Stem Cells Dev. 2012 Nov 20;21(17):3114-24. doi: 10.1089/scd.2012.0035. Epub 2012 Jul 13.


Stable isotope labelling with amino acids in cell culture for human embryonic stem cell proteomic analysis.

Harkness L, Prokhorova TA, Kassem M, Blagoev B.

Methods Mol Biol. 2012;873:297-305. doi: 10.1007/978-1-61779-794-1_20.


Procedures for derivation and characterisation of human embryonic stem cells from Odense, Denmark.

Harkness L, Kassem M.

Methods Mol Biol. 2012;873:33-51. doi: 10.1007/978-1-61779-794-1_3.


Identification of abnormal stem cells using Raman spectroscopy.

Harkness L, Novikov SM, Beermann J, Bozhevolnyi SI, Kassem M.

Stem Cells Dev. 2012 Aug 10;21(12):2152-9. doi: 10.1089/scd.2011.0600. Epub 2012 Feb 21.


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