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Items: 1 to 20 of 48

1.

Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen.

Menden MP, Wang D, Mason MJ, Szalai B, Bulusu KC, Guan Y, Yu T, Kang J, Jeon M, Wolfinger R, Nguyen T, Zaslavskiy M; AstraZeneca-Sanger Drug Combination DREAM Consortium, Jang IS, Ghazoui Z, Ahsen ME, Vogel R, Neto EC, Norman T, Tang EKY, Garnett MJ, Veroli GYD, Fawell S, Stolovitzky G, Guinney J, Dry JR, Saez-Rodriguez J.

Nat Commun. 2019 Jun 17;10(1):2674. doi: 10.1038/s41467-019-09799-2.

2.

The Cancer Drug Fraction of Metabolism Database.

Hua L, Chiang CW, Cong W, Li J, Wang X, Cheng L, Feng W, Quinney SK, Wang L, Li L.

CPT Pharmacometrics Syst Pharmacol. 2019 Jul;8(7):511-519. doi: 10.1002/psp4.12417. Epub 2019 Jun 17.

3.

Maize Dek33 encodes a pyrimidine reductase in riboflavin biosynthesis essential for oilbody formation and ABA biosynthesis during seed development.

Dai D, Tong H, Cheng L, Peng F, Zhang T, Qi W, Song R.

J Exp Bot. 2019 Jun 6. pii: erz268. doi: 10.1093/jxb/erz268. [Epub ahead of print]

PMID:
31173102
4.

Inhibition of enhancer of zeste homolog 2 (EZH2) overcomes enzalutamide resistance in castration-resistant prostate cancer.

Bai Y, Zhang Z, Cheng L, Wang R, Chen X, Kong Y, Feng F, Ahmad N, Li L, Liu X.

J Biol Chem. 2019 Jun 21;294(25):9911-9923. doi: 10.1074/jbc.RA119.008152. Epub 2019 May 13.

PMID:
31085587
5.

Lipid Modulating Anti-oxidant Stress Activity of Gastrodin on Nonalcoholic Fatty Liver Disease Larval Zebrafish Model.

Ahmad O, Wang B, Ma K, Deng Y, Li M, Yang L, Yang Y, Zhao J, Cheng L, Zhou Q, Shang J.

Int J Mol Sci. 2019 Apr 23;20(8). pii: E1984. doi: 10.3390/ijms20081984.

6.

NOTCH signaling is activated in and contributes to resistance in enzalutamide-resistant prostate cancer cells.

Farah E, Li C, Cheng L, Kong Y, Lanman NA, Pascuzzi P, Lorenz GR, Zhang Y, Ahmad N, Li L, Ratliff T, Liu X.

J Biol Chem. 2019 May 24;294(21):8543-8554. doi: 10.1074/jbc.RA118.006983. Epub 2019 Apr 2.

PMID:
30940724
7.

Characteristics, capability, and origin of shale gas desorption of the Longmaxi Formation in the southeastern Sichuan Basin, China.

Tang X, Jiang Z, Jiang S, Cheng L, Zhong N, Tang L, Chang J, Zhou W.

Sci Rep. 2019 Jan 31;9(1):1035. doi: 10.1038/s41598-018-37782-2.

8.

Integration of genomic copy number variations and chemotherapy-response biomarkers in pediatric sarcoma.

Cheng L, Pandya PH, Liu E, Chandra P, Wang L, Murray ME, Carter J, Ferguson M, Saadatzadeh MR, Bijangi-Visheshsaraei K, Marshall M, Li L, Pollok KE, Renbarger JL.

BMC Med Genomics. 2019 Jan 31;12(Suppl 1):23. doi: 10.1186/s12920-018-0456-5.

9.

The transcription factor POU3F2 regulates a gene coexpression network in brain tissue from patients with psychiatric disorders.

Chen C, Meng Q, Xia Y, Ding C, Wang L, Dai R, Cheng L, Gunaratne P, Gibbs RA, Min S, Coarfa C, Reid JG, Zhang C, Jiao C, Jiang Y, Giase G, Thomas A, Fitzgerald D, Brunetti T, Shieh A, Xia C, Wang Y, Wang Y, Badner JA, Gershon ES, White KP, Liu C.

Sci Transl Med. 2018 Dec 19;10(472). pii: eaat8178. doi: 10.1126/scitranslmed.aat8178. Epub 2018 Dec 13.

10.

Revealing the brain's molecular architecture.

PsychENCODE Consortium.

Science. 2018 Dec 14;362(6420):1262-1263. doi: 10.1126/science.362.6420.1262. No abstract available.

PMID:
30545881
11.

Comprehensive functional genomic resource and integrative model for the human brain.

Wang D, Liu S, Warrell J, Won H, Shi X, Navarro FCP, Clarke D, Gu M, Emani P, Yang YT, Xu M, Gandal MJ, Lou S, Zhang J, Park JJ, Yan C, Rhie SK, Manakongtreecheep K, Zhou H, Nathan A, Peters M, Mattei E, Fitzgerald D, Brunetti T, Moore J, Jiang Y, Girdhar K, Hoffman GE, Kalayci S, Gümüş ZH, Crawford GE; PsychENCODE Consortium, Roussos P, Akbarian S, Jaffe AE, White KP, Weng Z, Sestan N, Geschwind DH, Knowles JA, Gerstein MB.

Science. 2018 Dec 14;362(6420). pii: eaat8464. doi: 10.1126/science.aat8464.

12.

Transcriptome-wide isoform-level dysregulation in ASD, schizophrenia, and bipolar disorder.

Gandal MJ, Zhang P, Hadjimichael E, Walker RL, Chen C, Liu S, Won H, van Bakel H, Varghese M, Wang Y, Shieh AW, Haney J, Parhami S, Belmont J, Kim M, Moran Losada P, Khan Z, Mleczko J, Xia Y, Dai R, Wang D, Yang YT, Xu M, Fish K, Hof PR, Warrell J, Fitzgerald D, White K, Jaffe AE; PsychENCODE Consortium, Peters MA, Gerstein M, Liu C, Iakoucheva LM, Pinto D, Geschwind DH.

Science. 2018 Dec 14;362(6420). pii: eaat8127. doi: 10.1126/science.aat8127.

13.

Integrative functional genomic analysis of human brain development and neuropsychiatric risks.

Li M, Santpere G, Imamura Kawasawa Y, Evgrafov OV, Gulden FO, Pochareddy S, Sunkin SM, Li Z, Shin Y, Zhu Y, Sousa AMM, Werling DM, Kitchen RR, Kang HJ, Pletikos M, Choi J, Muchnik S, Xu X, Wang D, Lorente-Galdos B, Liu S, Giusti-Rodríguez P, Won H, de Leeuw CA, Pardiñas AF; BrainSpan Consortium; PsychENCODE Consortium; PsychENCODE Developmental Subgroup, Hu M, Jin F, Li Y, Owen MJ, O'Donovan MC, Walters JTR, Posthuma D, Reimers MA, Levitt P, Weinberger DR, Hyde TM, Kleinman JE, Geschwind DH, Hawrylycz MJ, State MW, Sanders SJ, Sullivan PF, Gerstein MB, Lein ES, Knowles JA, Sestan N.

Science. 2018 Dec 14;362(6420). pii: eaat7615. doi: 10.1126/science.aat7615.

14.

Transcriptome and epigenome landscape of human cortical development modeled in organoids.

Amiri A, Coppola G, Scuderi S, Wu F, Roychowdhury T, Liu F, Pochareddy S, Shin Y, Safi A, Song L, Zhu Y, Sousa AMM; PsychENCODE Consortium, Gerstein M, Crawford GE, Sestan N, Abyzov A, Vaccarino FM.

Science. 2018 Dec 14;362(6420). pii: eaat6720. doi: 10.1126/science.aat6720.

15.

Diversity and abundance of denitrifiers during cow manure composting.

Meng Q, Xu X, Zhang W, Cheng L, Men M, Xu B, Deng L, Sun X.

Rev Argent Microbiol. 2019 Jul - Sep;51(3):191-200. doi: 10.1016/j.ram.2018.08.003. Epub 2018 Nov 20.

16.

Modulation of Ion Channels in the Superior Cervical Ganglion Neurons by Myocardial Ischemia and Fluvastatin Treatment.

Cheng L, Wang X, Liu T, Tse G, Fu H, Li G.

Front Physiol. 2018 Sep 10;9:1157. doi: 10.3389/fphys.2018.01157. eCollection 2018.

17.

Distinct molecular pathways in ovarian endometrioid adenocarcinoma with concurrent endometriosis.

Zhang C, Wang X, Anaya Y, Parodi L, Cheng L, Anderson ML, Hawkins SM.

Int J Cancer. 2018 Nov 15;143(10):2505-2515. doi: 10.1002/ijc.31768. Epub 2018 Sep 21.

PMID:
30152524
18.

Three-Component Mixture Model-Based Adverse Drug Event Signal Detection for the Adverse Event Reporting System.

Zhang P, Li M, Chiang CW, Wang L, Xiang Y, Cheng L, Feng W, Schleyer TK, Quinney SK, Wu HY, Zeng D, Li L.

CPT Pharmacometrics Syst Pharmacol. 2018 Aug;7(8):499-506. doi: 10.1002/psp4.12294. Epub 2018 Aug 9.

19.

Inhibition of cholesterol biosynthesis overcomes enzalutamide resistance in castration-resistant prostate cancer (CRPC).

Kong Y, Cheng L, Mao F, Zhang Z, Zhang Y, Farah E, Bosler J, Bai Y, Ahmad N, Kuang S, Li L, Liu X.

J Biol Chem. 2018 Sep 14;293(37):14328-14341. doi: 10.1074/jbc.RA118.004442. Epub 2018 Aug 8.

20.

Inhibition of the Wnt/β-Catenin Pathway Overcomes Resistance to Enzalutamide in Castration-Resistant Prostate Cancer.

Zhang Z, Cheng L, Li J, Farah E, Atallah NM, Pascuzzi PE, Gupta S, Liu X.

Cancer Res. 2018 Jun 15;78(12):3147-3162. doi: 10.1158/0008-5472.CAN-17-3006. Epub 2018 Apr 26.

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