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A Combination of Tamarindus indica seeds and Curcuma longa Rhizome Extracts Improves Knee Joint Function and Alleviates Pain in Non-Arthritic Adults Following Physical Activity.

Rao PS, Ramanjaneyulu YS, Prisk VR, Schurgers LJ.

Int J Med Sci. 2019 Jun 2;16(6):845-853. doi: 10.7150/ijms.32505. eCollection 2019.


Vitamin K Antagonists, Non-Vitamin K Antagonist Oral Anticoagulants, and Vascular Calcification in Patients with Atrial Fibrillation.

Peeters FECM, Dudink EAMP, Kimenai DM, Weijs B, Altintas S, Heckman LIB, Mihl C, Schurgers LJ, Wildberger JE, Meex SJR, Kietselaer BLJH, Crijns HJGM.

TH Open. 2018 Nov 10;2(4):e391-e398. doi: 10.1055/s-0038-1675578. eCollection 2018 Oct.


Targeting Coagulation Factor Xa Promotes Regression of Advanced Atherosclerosis in Apolipoprotein-E Deficient Mice.

Posthuma JJ, Posma JJN, van Oerle R, Leenders P, van Gorp RH, Jaminon AMG, Mackman N, Heitmeier S, Schurgers LJ, Ten Cate H, Spronk HMH.

Sci Rep. 2019 Mar 7;9(1):3909. doi: 10.1038/s41598-019-40602-w.


The Bone-Vasculature Axis: Calcium Supplementation and the Role of Vitamin K.

Wasilewski GB, Vervloet MG, Schurgers LJ.

Front Cardiovasc Med. 2019 Feb 5;6:6. doi: 10.3389/fcvm.2019.00006. eCollection 2019. Review.


Annexin A1 as Neuroprotective Determinant for Blood-Brain Barrier Integrity in Neonatal Hypoxic-Ischemic Encephalopathy.

Gussenhoven R, Klein L, Ophelders DRMG, Habets DHJ, Giebel B, Kramer BW, Schurgers LJ, Reutelingsperger CPM, Wolfs TGAM.

J Clin Med. 2019 Jan 24;8(2). pii: E137. doi: 10.3390/jcm8020137.


Effect of 6-Month Vitamin D Supplementation on Plasma Matrix Gla Protein in Older Adults.

van Ballegooijen AJ, Beulens JWJ, Schurgers LJ, de Koning EJ, Lips P, van Schoor NM, Vervloet MG.

Nutrients. 2019 Jan 22;11(2). pii: E231. doi: 10.3390/nu11020231.


Target identification for the diagnosis and intervention of vulnerable atherosclerotic plaques beyond 18F-fluorodeoxyglucose positron emission tomography imaging: promising tracers on the horizon.

Bucerius J, Dijkgraaf I, Mottaghy FM, Schurgers LJ.

Eur J Nucl Med Mol Imaging. 2019 Jan;46(1):251-265. doi: 10.1007/s00259-018-4176-z. Epub 2018 Oct 9.


Missense mutation of VKORC1 leads to medial arterial calcification in rats.

Michaux A, Matagrin B, Debaux JV, Schurgers LJ, Benoit E, Lattard V.

Sci Rep. 2018 Sep 13;8(1):13733. doi: 10.1038/s41598-018-31788-6.


The role of kidney transplantation and phosphate binder use in vitamin K status.

Jansz TT, Neradova A, van Ballegooijen AJ, Verhaar MC, Vervloet MG, Schurgers LJ, van Jaarsveld BC.

PLoS One. 2018 Aug 30;13(8):e0203157. doi: 10.1371/journal.pone.0203157. eCollection 2018.


Renal matrix Gla protein expression increases progressively with CKD and predicts renal outcome.

Miyata KN, Nast CC, Dai T, Dukkipati R, LaPage JA, Troost JP, Schurgers LJ, Kretzler M, Adler SG.

Exp Mol Pathol. 2018 Aug;105(1):120-129. doi: 10.1016/j.yexmp.2018.07.001. Epub 2018 Jul 6.


A Novel Biomimetic Tool for Assessing Vitamin K Status Based on Molecularly Imprinted Polymers.

Eersels K, Diliën H, Lowdon JW, Steen Redeker E, Rogosic R, Heidt B, Peeters M, Cornelis P, Lux P, Reutelingsperger CP, Schurgers LJ, Cleij TJ, van Grinsven B.

Nutrients. 2018 Jun 11;10(6). pii: E751. doi: 10.3390/nu10060751.


Decreased Levels of Circulating Carboxylated Osteocalcin in Children with Low Energy Fractures: A Pilot Study.

Popko J, Karpiński M, Chojnowska S, Maresz K, Milewski R, Badmaev V, Schurgers LJ.

Nutrients. 2018 Jun 6;10(6). pii: E734. doi: 10.3390/nu10060734.


Initiation and Propagation of Vascular Calcification Is Regulated by a Concert of Platelet- and Smooth Muscle Cell-Derived Extracellular Vesicles.

Schurgers LJ, Akbulut AC, Kaczor DM, Halder M, Koenen RR, Kramann R.

Front Cardiovasc Med. 2018 Apr 6;5:36. doi: 10.3389/fcvm.2018.00036. eCollection 2018.


Ucma/GRP inhibits phosphate-induced vascular smooth muscle cell calcification via SMAD-dependent BMP signalling.

Willems BA, Furmanik M, Caron MMJ, Chatrou MLL, Kusters DHM, Welting TJM, Stock M, Rafael MS, Viegas CSB, Simes DC, Vermeer C, Reutelingsperger CPM, Schurgers LJ.

Sci Rep. 2018 Mar 21;8(1):4961. doi: 10.1038/s41598-018-23353-y.


Bicuspid Aortic Valve Stenosis and the Effect of Vitamin K2 on Calcification Using 18F-Sodium Fluoride Positron Emission Tomography/Magnetic Resonance: The BASIK2 Rationale and Trial Design.

Peeters FECM, van Mourik MJW, Meex SJR, Bucerius J, Schalla SM, Gerretsen SC, Mihl C, Dweck MR, Schurgers LJ, Wildberger JE, Crijns HJGM, Kietselaer BLJH.

Nutrients. 2018 Mar 21;10(4). pii: E386. doi: 10.3390/nu10040386.


Influence of pH and phosphate concentration on the phosphate binding capacity of five contemporary binders. An in vitro study.

Schumacher SP, Schurgers LJ, Vervloet MG, Neradova A.

Nephrology (Carlton). 2019 Feb;24(2):221-226. doi: 10.1111/nep.13245. Epub 2018 Apr 6.


Use of Cyclic Backbone NGR-Based SPECT to Increase Efficacy of Postmyocardial Infarction Angiogenesis Imaging.

Hendrikx G, Hackeng TM, van Gorp R, Bauwens M, Schurgers LJ, Mottaghy FM, Post MJ, Dijkgraaf I.

Contrast Media Mol Imaging. 2017 Oct 24;2017:8638549. doi: 10.1155/2017/8638549. eCollection 2017.


Calcific aortic valve stenosis: hard disease in the heart: A biomolecular approach towards diagnosis and treatment.

Peeters FECM, Meex SJR, Dweck MR, Aikawa E, Crijns HJGM, Schurgers LJ, Kietselaer BLJH.

Eur Heart J. 2018 Jul 21;39(28):2618-2624. doi: 10.1093/eurheartj/ehx653.


Platelet extracellular vesicles induce a pro-inflammatory smooth muscle cell phenotype.

Vajen T, Benedikter BJ, Heinzmann ACA, Vasina EM, Henskens Y, Parsons M, Maguire PB, Stassen FR, Heemskerk JWM, Schurgers LJ, Koenen RR.

J Extracell Vesicles. 2017 May 16;6(1):1322454. doi: 10.1080/20013078.2017.1322454. eCollection 2017.


Slower Progress of Aortic Valve Calcification With Vitamin K Supplementation: Results From a Prospective Interventional Proof-of-Concept Study.

Brandenburg VM, Reinartz S, Kaesler N, Krüger T, Dirrichs T, Kramann R, Peeters F, Floege J, Keszei A, Marx N, Schurgers LJ, Koos R.

Circulation. 2017 May 23;135(21):2081-2083. doi: 10.1161/CIRCULATIONAHA.116.027011. No abstract available.


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