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Items: 3

1.

Structurally Simple, Readily Available Peptidomimetic 1-Benzyl-5-methyl-4-( n-octylamino)pyrimidin-2(1 H)-one Exhibited Efficient Cardioprotection in a Myocardial Ischemia (MI) Mouse Model.

Trifonov L, Nudelman V, Zhenin M, Matsree E, Afri M, Schmerling B, Cohen G, Jozwiak K, Weitman M, Korshin E, Senderowitz H, Shainberg A, Hochhauser E, Gruzman A.

J Med Chem. 2018 Dec 27;61(24):11309-11326. doi: 10.1021/acs.jmedchem.8b01471. Epub 2018 Dec 11.

PMID:
30507195
2.

An Expedient Synthesis of CMF-019: (S)-5-Methyl-3-{1-(pentan-3-yl)-2- (thiophen-2-ylmethyl)-1H-benzo[d]imidazole-5-carboxamido}hexanoic Acid, a Potent Apelin Receptor (APJ) Agonist.

Trifonov L, Afri M, Palczewski K, Korshin EE, Gruzman A.

Med Chem. 2018;14(7):688-694. doi: 10.2174/1573406414666180412154952.

PMID:
29651942
3.

A DJ-1 Based Peptide Attenuates Dopaminergic Degeneration in Mice Models of Parkinson's Disease via Enhancing Nrf2.

Lev N, Barhum Y, Ben-Zur T, Aharony I, Trifonov L, Regev N, Melamed E, Gruzman A, Offen D.

PLoS One. 2015 May 29;10(5):e0127549. doi: 10.1371/journal.pone.0127549. eCollection 2015.

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