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Items: 12


The Expressions of Dickkopf-Related Protein 1 and Frizzled-Related Protein Are Negatively Correlated to Local Inflammation and Osteoarthritis Severity.

Huang X, Zhong L, van Helvoort E, Lafeber F, Mastbergen S, Hendriks J, Post JN, Karperien M.

Cartilage. 2019 Apr 4:1947603519841676. doi: 10.1177/1947603519841676. [Epub ahead of print]


Periarticular Mesenchymal Progenitors Initiate and Contribute to Secondary Ossification Center Formation During Mouse Long Bone Development.

Tong W, Tower RJ, Chen C, Wang L, Zhong L, Wei Y, Sun H, Cao G, Jia H, Pacifici M, Koyama E, Enomoto-Iwamoto M, Qin L.

Stem Cells. 2019 May;37(5):677-689. doi: 10.1002/stem.2975. Epub 2019 Feb 6.


Different response of human chondrocytes from healthy looking areas and damaged regions to IL1β stimulation under different oxygen tension.

Huang X, Zhong L, Hendriks J, Post JN, Karperien M.

J Orthop Res. 2019 Jan;37(1):84-93. doi: 10.1002/jor.24142. Epub 2018 Oct 1.


The Effects of the WNT-Signaling Modulators BIO and PKF118-310 on the Chondrogenic Differentiation of Human Mesenchymal Stem Cells.

Huang X, Zhong L, Hendriks J, Post JN, Karperien M.

Int J Mol Sci. 2018 Feb 13;19(2). pii: E561. doi: 10.3390/ijms19020561.


Promoted Chondrogenesis of Cocultured Chondrocytes and Mesenchymal Stem Cells under Hypoxia Using In-situ Forming Degradable Hydrogel Scaffolds.

Huang X, Hou Y, Zhong L, Huang D, Qian H, Karperien M, Chen W.

Biomacromolecules. 2018 Jan 8;19(1):94-102. doi: 10.1021/acs.biomac.7b01271. Epub 2017 Dec 18.


Nitric Oxide Mediates Crosstalk between Interleukin 1β and WNT Signaling in Primary Human Chondrocytes by Reducing DKK1 and FRZB Expression.

Zhong L, Schivo S, Huang X, Leijten J, Karperien M, Post JN.

Int J Mol Sci. 2017 Nov 22;18(11). pii: E2491. doi: 10.3390/ijms18112491.


Proteasome inhibitor bortezomib is a novel therapeutic agent for focal radiation-induced osteoporosis.

Chandra A, Wang L, Young T, Zhong L, Tseng WJ, Levine MA, Cengel K, Liu XS, Zhang Y, Pignolo RJ, Qin L.

FASEB J. 2018 Jan;32(1):52-62. doi: 10.1096/fj.201700375R. Epub 2017 Aug 31.


Endogenous DKK1 and FRZB Regulate Chondrogenesis and Hypertrophy in Three-Dimensional Cultures of Human Chondrocytes and Human Mesenchymal Stem Cells.

Zhong L, Huang X, Rodrigues ED, Leijten JC, Verrips T, El Khattabi M, Karperien M, Post JN.

Stem Cells Dev. 2016 Dec 1;25(23):1808-1817. Epub 2016 Oct 27.


Correlation between Gene Expression and Osteoarthritis Progression in Human.

Zhong L, Huang X, Karperien M, Post JN.

Int J Mol Sci. 2016 Jul 14;17(7). pii: E1126. doi: 10.3390/ijms17071126.


The Regulatory Role of Signaling Crosstalk in Hypertrophy of MSCs and Human Articular Chondrocytes.

Zhong L, Huang X, Karperien M, Post JN.

Int J Mol Sci. 2015 Aug 14;16(8):19225-47. doi: 10.3390/ijms160819225. Review.


T cell factor 4 is a pro-catabolic and apoptotic factor in human articular chondrocytes by potentiating nuclear factor κB signaling.

Ma B, Zhong L, van Blitterswijk CA, Post JN, Karperien M.

J Biol Chem. 2013 Jun 14;288(24):17552-8. doi: 10.1074/jbc.M113.453985. Epub 2013 Apr 19.

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