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A New Topical Eye Drop Containing LyeTxI-b, A Synthetic Peptide Designed from A Lycosa erithrognata Venom Toxin, Was Effective to Treat Resistant Bacterial Keratitis.

Silva CND, Silva FRD, Dourado LFN, Reis PVMD, Silva RO, Costa BLD, Nunes PS, Amaral FA, Santos VLD, de Lima ME, Silva Cunha JĂșnior AD.

Toxins (Basel). 2019 Apr 4;11(4). pii: E203. doi: 10.3390/toxins11040203.


Corosolic acid: antiangiogenic activity and safety of intravitreal injection in rats eyes.

Toledo CR, Pereira VV, Dourado LFN, Paiva MRB, Silva-Cunha A.

Doc Ophthalmol. 2019 Jun;138(3):181-194. doi: 10.1007/s10633-019-09682-x. Epub 2019 Feb 26.


Intravitreal injection of the synthetic peptide LyeTx I b, derived from a spider toxin, into the rabbit eye is safe and prevents neovascularization in a chorio-allantoic membrane model.

Silva FRD, Paiva MRB, Dourado LFN, Silva RO, Silva CND, Costa BLD, Toledo CR, de Lima ME, Silva-Cunha AD.

J Venom Anim Toxins Incl Trop Dis. 2018 Nov 21;24:31. doi: 10.1186/s40409-018-0168-5. eCollection 2018.

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