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Items: 1 to 20 of 84

1.

Potent and Broad but not Unselective Cleavage of Cytokines and Chemokines by Human Neutrophil Elastase and Proteinase 3.

Fu Z, Akula S, Thorpe M, Hellman L.

Int J Mol Sci. 2020 Jan 19;21(2). pii: E651. doi: 10.3390/ijms21020651.

2.

Quantitative In-Depth Analysis of the Mouse Mast Cell Transcriptome Reveals Organ-Specific Mast Cell Heterogeneity.

Akula S, Paivandy A, Fu Z, Thorpe M, Pejler G, Hellman L.

Cells. 2020 Jan 14;9(1). pii: E211. doi: 10.3390/cells9010211.

3.

Extended cleavage specificities of two mast cell chymase-related proteases and one granzyme B-like protease from the platypus, a monotreme.

Fu Z, Akula S, Thorpe M, Hellman L.

Int J Mol Sci. 2020 Jan 2;21(1). pii: E319. doi: 10.3390/ijms21010319.

4.

Protective role of mouse mast cell tryptase Mcpt6 in melanoma.

Grujic M, Hellman L, Gustafson AM, Akula S, Melo FR, Pejler G.

Pigment Cell Melanoma Res. 2020 Jan 1. doi: 10.1111/pcmr.12859. [Epub ahead of print]

PMID:
31894627
5.

Extended Cleavage Specificities of Rabbit and Guinea Pig Mast Cell Chymases: Two Highly Specific Leu-Ases.

Zhongwei Y, Akula S, Fu Z, de Garavilla L, Kervinen J, Thorpe M, Hellman L.

Int J Mol Sci. 2019 Dec 16;20(24). pii: E6340. doi: 10.3390/ijms20246340.

6.
7.

Novel aspects of mast cell and basophil function: Highlights from the 9th meeting of the European Mast Cell and Basophil Research Network (EMBRN)-A Marcus Wallenberg Symposium.

Hallgren J, Hellman L, Maurer M, Nilsson GP, Wernersson S, Åbrink M, Pejler G.

Allergy. 2019 Sep 26. doi: 10.1111/all.14065. [Epub ahead of print] No abstract available.

PMID:
31557323
8.

Extended cleavage specificities of mast cell proteases 1 and 2 from golden hamster: Classical chymase and an elastolytic protease comparable to rat and mouse MCP-5.

Thorpe M, Fu Z, Albat E, Akula S, de Garavilla L, Kervinen J, Hellman L.

PLoS One. 2018 Dec 6;13(12):e0207826. doi: 10.1371/journal.pone.0207826. eCollection 2018.

9.

Extended cleavage specificity of sheep mast cell protease-2: A classical chymase with preference to aromatic P1 substrate residues.

Fu Z, Akula S, Thorpe M, Chahal G, de Garavilla L, Kervinen J, Hellman L.

Dev Comp Immunol. 2019 Mar;92:160-169. doi: 10.1016/j.dci.2018.11.019. Epub 2018 Nov 24.

PMID:
30481523
10.
11.

Cleavage specificity of recombinant Giardia intestinalis cysteine proteases: Degradation of immunoglobulins and defensins.

Liu J, Fu Z, Hellman L, Svärd SG.

Mol Biochem Parasitol. 2019 Jan;227:29-38. doi: 10.1016/j.molbiopara.2018.10.004. Epub 2018 Nov 17.

PMID:
30458129
12.

Secreted Giardia intestinalis cysteine proteases disrupt intestinal epithelial cell junctional complexes and degrade chemokines.

Liu J, Ma'ayeh S, Peirasmaki D, Lundström-Stadelmann B, Hellman L, Svärd SG.

Virulence. 2018 Dec 31;9(1):879-894. doi: 10.1080/21505594.2018.1451284.

13.

Extended cleavage specificity of human neutrophil cathepsin G: A low activity protease with dual chymase and tryptase-type specificities.

Thorpe M, Fu Z, Chahal G, Akula S, Kervinen J, de Garavilla L, Hellman L.

PLoS One. 2018 Apr 13;13(4):e0195077. doi: 10.1371/journal.pone.0195077. eCollection 2018.

14.

Tracing the Origins of IgE, Mast Cells, and Allergies by Studies of Wild Animals.

Hellman LT, Akula S, Thorpe M, Fu Z.

Front Immunol. 2017 Dec 19;8:1749. doi: 10.3389/fimmu.2017.01749. eCollection 2017. Review.

15.

The Appearance and Diversification of Receptors for IgM During Vertebrate Evolution.

Akula S, Hellman L.

Curr Top Microbiol Immunol. 2017;408:1-23. doi: 10.1007/82_2017_22. Review.

PMID:
28884191
16.

Highly Selective Cleavage of Cytokines and Chemokines by the Human Mast Cell Chymase and Neutrophil Cathepsin G.

Fu Z, Thorpe M, Alemayehu R, Roy A, Kervinen J, de Garavilla L, Åbrink M, Hellman L.

J Immunol. 2017 Feb 15;198(4):1474-1483. doi: 10.4049/jimmunol.1601223. Epub 2017 Jan 4.

17.

Development of a novel therapeutic vaccine carrier that sustains high antibody titers against several targets simultaneously.

Saupe F, Reichel M, Huijbers EJ, Femel J, Markgren PO, Andersson CE, Deindl S, Danielson UH, Hellman LT, Olsson AK.

FASEB J. 2017 Mar;31(3):1204-1214. doi: 10.1096/fj.201600820R. Epub 2016 Dec 19.

PMID:
27993994
18.

Channel catfish granzyme-like I is a highly specific serine protease with metase activity that is expressed by fish NK-like cells.

Thorpe M, Akula S, Hellman L.

Dev Comp Immunol. 2016 Oct;63:84-95. doi: 10.1016/j.dci.2016.05.013. Epub 2016 May 20.

PMID:
27216028
19.

Asp-ase Activity of the Opossum Granzyme B Supports the Role of Granzyme B as Part of Anti-Viral Immunity Already during Early Mammalian Evolution.

Fu Z, Thorpe M, Akula S, Hellman L.

PLoS One. 2016 May 6;11(5):e0154886. doi: 10.1371/journal.pone.0154886. eCollection 2016.

20.

Correction: Granule Associated Serine Proteases of Hematopoietic Cells - An Analysis of Their Appearance and Diversification during Vertebrate Evolution.

Akula S, Thorpe M, Boinapally V, Hellman L.

PLoS One. 2015 Dec 22;10(12):e0145592. doi: 10.1371/journal.pone.0145592. eCollection 2015. No abstract available.

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