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Items: 11


Design, Modeling and Synthesis of 1,2,3-Triazole-Linked Nucleoside-Amino Acid Conjugates as Potential Antibacterial Agents.

Malkowski SN, Dishuck CF, Lamanilao GG, Embry CP, Grubb CS, Cafiero M, Peterson LW.

Molecules. 2017 Oct 10;22(10). pii: E1682. doi: 10.3390/molecules22101682.


Degradable hybrid materials based on cationic acylhydrazone dynamic covalent polymers promote DNA complexation through multivalent interactions.

Bouillon C, Paolantoni D, Rote JC, Bessin Y, Peterson LW, Dumy P, Ulrich S.

Chemistry. 2014 Nov 3;20(45):14705-14. doi: 10.1002/chem.201403695. Epub 2014 Sep 22.


Steric restrictions of RISC in RNA interference identified with size-expanded RNA nucleobases.

HernĂ¡ndez AR, Peterson LW, Kool ET.

ACS Chem Biol. 2012 Aug 17;7(8):1454-61. doi: 10.1021/cb300174c. Epub 2012 Jun 12.


Encoding phenotype in bacteria with an alternative genetic set.

Krueger AT, Peterson LW, Chelliserry J, Kleinbaum DJ, Kool ET.

J Am Chem Soc. 2011 Nov 16;133(45):18447-51. doi: 10.1021/ja208025e. Epub 2011 Oct 21.


Tyrosine-based 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]cytosine and -adenine ((S)-HPMPC and (S)-HPMPA) prodrugs: synthesis, stability, antiviral activity, and in vivo transport studies.

Zakharova VM, Serpi M, Krylov IS, Peterson LW, Breitenbach JM, Borysko KZ, Drach JC, Collins M, Hilfinger JM, Kashemirov BA, McKenna CE.

J Med Chem. 2011 Aug 25;54(16):5680-93. doi: 10.1021/jm2001426. Epub 2011 Aug 3.


Synthesis, transport and antiviral activity of Ala-Ser and Val-Ser prodrugs of cidofovir.

Peterson LW, Kim JS, Kijek P, Mitchell S, Hilfinger J, Breitenbach J, Borysko K, Drach JC, Kashemirov BA, McKenna CE.

Bioorg Med Chem Lett. 2011 Jul 1;21(13):4045-9. doi: 10.1016/j.bmcl.2011.04.126. Epub 2011 May 3.


Serine side chain-linked peptidomimetic conjugates of cyclic HPMPC and HPMPA: synthesis and interaction with hPEPT1.

Peterson LW, Sala-Rabanal M, Krylov IS, Serpi M, Kashemirov BA, McKenna CE.

Mol Pharm. 2010 Dec 6;7(6):2349-61. doi: 10.1021/mp100186b. Epub 2010 Oct 7.


Modifications to the dNTP triphosphate moiety: from mechanistic probes for DNA polymerases to antiviral and anti-cancer drug design.

McKenna CE, Kashemirov BA, Peterson LW, Goodman MF.

Biochim Biophys Acta. 2010 May;1804(5):1223-30. doi: 10.1016/j.bbapap.2010.01.005. Epub 2010 Jan 14. Review.


Puromycin-sensitive aminopeptidase: an antiviral prodrug activating enzyme.

Tehler U, Nelson CH, Peterson LW, Provoda CJ, Hilfinger JM, Lee KD, McKenna CE, Amidon GL.

Antiviral Res. 2010 Mar;85(3):482-9. doi: 10.1016/j.antiviral.2009.12.003. Epub 2009 Dec 5.


Prodrug approaches to improving the oral absorption of antiviral nucleotide analogues.

Peterson LW, McKenna CE.

Expert Opin Drug Deliv. 2009 Apr;6(4):405-20. doi: 10.1517/17425240902824808 . Review.


Serine peptide phosphoester prodrugs of cyclic cidofovir: synthesis, transport, and antiviral activity.

Eriksson U, Peterson LW, Kashemirov BA, Hilfinger JM, Drach JC, Borysko KZ, Breitenbach JM, Kim JS, Mitchell S, Kijek P, McKenna CE.

Mol Pharm. 2008 Jul-Aug;5(4):598-609. doi: 10.1021/mp8000099. Epub 2008 May 16.

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