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Items: 1 to 20 of 143


Methylene blue as a far-red light-mediated photocleavable multifunctional ligand.

Dao HM, Whang CH, Shankar VK, Wang YH, Khan IA, Walker LA, Husain I, Khan SI, Murthy SN, Jo S.

Chem Commun (Camb). 2020 Feb 6;56(11):1673-1676. doi: 10.1039/c9cc08916k.


In search for potential antidiabetic compounds from natural sources: docking, synthesis and biological screening of small molecules from Lycium spp. (Goji).

Yalamanchili C, Chittiboyina AG, Haider S, Vasquez Y, Khan S, do Carmo JM, da Silva AA, Pinkerton M, Hall JE, Walker LA, Khan IA.

Heliyon. 2019 Dec 27;6(1):e02782. doi: 10.1016/j.heliyon.2019.e02782. eCollection 2020 Jan.


NPC1161B, an 8-Aminoquinoline Analog, Is Metabolized in the Mosquito and Inhibits Plasmodium falciparum Oocyst Maturation.

Hamerly T, Tweedell RE, Hritzo B, Nyasembe VO, Tekwani BL, Nanayakkara NPD, Walker LA, Dinglasan RR.

Front Pharmacol. 2019 Oct 25;10:1265. doi: 10.3389/fphar.2019.01265. eCollection 2019.


Paradoxical Patterns of Sinusoidal Obstruction Syndrome-Like Liver Injury in Aged Female CD-1 Mice Triggered by Cannabidiol-Rich Cannabis Extract and Acetaminophen Co-Administration.

Ewing LE, McGill MR, Yee EU, Quick CM, Skinner CM, Kennon-McGill S, Clemens M, Vazquez JH, McCullough SS, Williams DK, Kutanzi KR, Walker LA, ElSohly MA, James LP, Gurley BJ, Koturbash I.

Molecules. 2019 Jun 17;24(12). pii: E2256. doi: 10.3390/molecules24122256.


Hepatotoxicity of a Cannabidiol-Rich Cannabis Extract in the Mouse Model.

Ewing LE, Skinner CM, Quick CM, Kennon-McGill S, McGill MR, Walker LA, ElSohly MA, Gurley BJ, Koturbash I.

Molecules. 2019 Apr 30;24(9). pii: E1694. doi: 10.3390/molecules24091694.


Formation primaquine-5,6-orthoquinone, the putative active and toxic metabolite of primaquine via direct oxidation in human erythrocytes.

Fasinu PS, Nanayakkara NPD, Wang YH, Chaurasiya ND, Herath HMB, McChesney JD, Avula B, Khan I, Tekwani BL, Walker LA.

Malar J. 2019 Jan 30;18(1):30. doi: 10.1186/s12936-019-2658-5.


Metabolism of primaquine in normal human volunteers: investigation of phase I and phase II metabolites from plasma and urine using ultra-high performance liquid chromatography-quadrupole time-of-flight mass spectrometry.

Avula B, Tekwani BL, Chaurasiya ND, Fasinu P, Dhammika Nanayakkara NP, Bhandara Herath HMT, Wang YH, Bae JY, Khan SI, Elsohly MA, McChesney JD, Zimmerman PA, Khan IA, Walker LA.

Malar J. 2018 Aug 13;17(1):294. doi: 10.1186/s12936-018-2433-z.


Unequivocal determination of caulamidines A and B: application and validation of new tools in the structure elucidation tool box.

Milanowski DJ, Oku N, Cartner LK, Bokesch HR, Williamson RT, Saurí J, Liu Y, Blinov KA, Ding Y, Li XC, Ferreira D, Walker LA, Khan S, Davies-Coleman MT, Kelley JA, McMahon JB, Martin GE, Gustafson KR.

Chem Sci. 2017 Nov 6;9(2):307-314. doi: 10.1039/c7sc01996c. eCollection 2018 Jan 14.


Emerging therapeutic potential of graviola and its constituents in cancers.

Qazi AK, Siddiqui JA, Jahan R, Chaudhary S, Walker LA, Sayed Z, Jones DT, Batra SK, Macha MA.

Carcinogenesis. 2018 Apr 5;39(4):522-533. doi: 10.1093/carcin/bgy024. Review.


Modulation of Cytochrome P450, P-glycoprotein and Pregnane X Receptor by Selected Antimalarial Herbs-Implication for Herb-Drug Interaction.

Fasinu PS, Manda VK, Dale OR, Egiebor NO, Walker LA, Khan SI.

Molecules. 2017 Nov 23;22(12). pii: E2049. doi: 10.3390/molecules22122049.


Interactions of Desmethoxyyangonin, a Secondary Metabolite from Renealmia alpinia, with Human Monoamine Oxidase-A and Oxidase-B.

Chaurasiya ND, León F, Ding Y, Gómez-Betancur I, Benjumea D, Walker LA, Cutler SJ, Tekwani BL.

Evid Based Complement Alternat Med. 2017;2017:4018724. doi: 10.1155/2017/4018724. Epub 2017 Aug 24.


PXR mediated induction of CYP3A4, CYP1A2, and P-gp by Mitragyna speciosa and its alkaloids.

Manda VK, Avula B, Dale OR, Ali Z, Khan IA, Walker LA, Khan SI.

Phytother Res. 2017 Dec;31(12):1935-1945. doi: 10.1002/ptr.5942. Epub 2017 Oct 26.


Inhibitors of ubiquitin E3 ligase as potential new antimalarial drug leads.

Jain J, Jain SK, Walker LA, Tekwani BL.

BMC Pharmacol Toxicol. 2017 Jun 2;18(1):40. doi: 10.1186/s40360-017-0147-4.


Cannabis cultivation: Methodological issues for obtaining medical-grade product.

Chandra S, Lata H, ElSohly MA, Walker LA, Potter D.

Epilepsy Behav. 2017 May;70(Pt B):302-312. doi: 10.1016/j.yebeh.2016.11.029. Epub 2017 Feb 13. Review.


Both Phenolic and Non-phenolic Green Tea Fractions Inhibit Migration of Cancer Cells.

Seo EJ, Wu CF, Ali Z, Wang YH, Khan SI, Walker LA, Khan IA, Efferth T.

Front Pharmacol. 2016 Nov 3;7:398. doi: 10.3389/fphar.2016.00398. eCollection 2016.


Proteoform-Specific Protein Binding of Small Molecules in Complex Matrices.

Gil G, Mao P, Avula B, Ali Z, Chittiboyina AG, Khan IA, Walker LA, Wang D.

ACS Chem Biol. 2017 Feb 17;12(2):389-397. doi: 10.1021/acschembio.6b01018. Epub 2016 Dec 21.


Mechanism for neurotropic action of vorinostat, a pan histone deacetylase inhibitor.

Shukla S, Shariat-Madar Z, Walker LA, Tekwani BL.

Mol Cell Neurosci. 2016 Dec;77:11-20. doi: 10.1016/j.mcn.2016.09.003. Epub 2016 Sep 24.


Isolation of Acacetin from Calea urticifolia with Inhibitory Properties against Human Monoamine Oxidase-A and -B.

Chaurasiya ND, Gogineni V, Elokely KM, León F, Núñez MJ, Klein ML, Walker LA, Cutler SJ, Tekwani BL.

J Nat Prod. 2016 Oct 28;79(10):2538-2544. Epub 2016 Oct 18.


Pathway-specific inhibition of primaquine metabolism by chloroquine/quinine.

Fasinu PS, Tekwani BL, Avula B, Chaurasiya ND, Nanayakkara NP, Wang YH, Khan IA, Walker LA.

Malar J. 2016 Sep 13;15:466. doi: 10.1186/s12936-016-1509-x.


Single-Dose Primaquine in a Preclinical Model of Glucose-6-Phosphate Dehydrogenase Deficiency: Implications for Use in Malaria Transmission-Blocking Programs.

Wickham KS, Baresel PC, Marcsisin SR, Sousa J, Vuong CT, Reichard GA, Campo B, Tekwani BL, Walker LA, Rochford R.

Antimicrob Agents Chemother. 2016 Sep 23;60(10):5906-13. doi: 10.1128/AAC.00600-16. Print 2016 Oct.

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