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Items: 1 to 20 of 47

1.

Searching for improved mimetic peptides inhibitors preventing conformational transition of amyloid-β42 monomer.

Gera J, Szögi T, Bozsó Z, Fülöp L, Barrera EE, Rodriguez AM, Méndez L, Delpiccolo CML, Mata EG, Cioffi F, Broersen K, Paragi G, Enriz RD.

Bioorg Chem. 2018 Aug 18;81:211-221. doi: 10.1016/j.bioorg.2018.08.018. [Epub ahead of print]

PMID:
30144634
2.

Niosomes decorated with dual ligands targeting brain endothelial transporters increase cargo penetration across the blood-brain barrier.

Mészáros M, Porkoláb G, Kiss L, Pilbat AM, Kóta Z, Kupihár Z, Kéri A, Galbács G, Siklós L, Tóth A, Fülöp L, Csete M, Sipos Á, Hülper P, Sipos P, Páli T, Rákhely G, Szabó-Révész P, Deli MA, Veszelka S.

Eur J Pharm Sci. 2018 Oct 15;123:228-240. doi: 10.1016/j.ejps.2018.07.042. Epub 2018 Jul 20.

PMID:
30031862
3.

Peripheral cyclic β-amino acids balance the stability and edge-protection of β-sandwiches.

Olajos G, Hetényi A, Wéber E, Szögi T, Fülöp L, Martinek TA.

Org Biomol Chem. 2018 Aug 1;16(30):5492-5499. doi: 10.1039/c8ob01322e.

PMID:
30024580
4.

Exceptional in vivo catabolism of neurodegeneration-related aggregates.

Datki Z, Olah Z, Hortobagyi T, Macsai L, Zsuga K, Fulop L, Bozso Z, Galik B, Acs E, Foldi A, Szarvas A, Kalman J.

Acta Neuropathol Commun. 2018 Jan 29;6(1):6. doi: 10.1186/s40478-018-0507-3.

5.

GABAA receptor subunit deregulation in the hippocampus of human foetuses with Down syndrome.

Milenkovic I, Stojanovic T, Aronica E, Fülöp L, Bozsó Z, Máté Z, Yanagawa Y, Adle-Biassette H, Lubec G, Szabó G, Harkany T, Kovács GG, Keimpema E.

Brain Struct Funct. 2018 Apr;223(3):1501-1518. doi: 10.1007/s00429-017-1563-3. Epub 2017 Nov 22.

6.

Studies for Improving a Rat Model of Alzheimer's Disease: Icv Administration of Well-Characterized β-Amyloid 1-42 Oligomers Induce Dysfunction in Spatial Memory.

Kasza Á, Penke B, Frank Z, Bozsó Z, Szegedi V, Hunya Á, Németh K, Kozma G, Fülöp L.

Molecules. 2017 Nov 18;22(11). pii: E2007. doi: 10.3390/molecules22112007.

7.

β-Amyloid and the Pathomechanisms of Alzheimer's Disease: A Comprehensive View.

Penke B, Bogár F, Fülöp L.

Molecules. 2017 Oct 10;22(10). pii: E1692. doi: 10.3390/molecules22101692. Review.

8.

Biotin and Glutathione Targeting of Solid Nanoparticles to Cross Human Brain Endothelial Cells.

Veszelka S, Meszaros M, Kiss L, Kota Z, Pali T, Hoyk Z, Bozso Z, Fulop L, Toth A, Rakhely G, Deli MA.

Curr Pharm Des. 2017;23(28):4198-4205. doi: 10.2174/1381612823666170727144450. Review.

PMID:
28748755
9.

The Role of Sigma-1 Receptor, an Intracellular Chaperone in Neurodegenerative Diseases.

Penke B, Fulop L, Szucs M, Frecska E.

Curr Neuropharmacol. 2018;16(1):97-116. doi: 10.2174/1570159X15666170529104323. Review.

10.

Multivalent foldamer-based affinity assay for selective recognition of Aβ oligomers.

Olajos G, Bartus É, Schuster I, Lautner G, Gyurcsányi RE, Szögi T, Fülöp L, Martinek TA.

Anal Chim Acta. 2017 Apr 1;960:131-137. doi: 10.1016/j.aca.2017.01.013. Epub 2017 Jan 24.

PMID:
28193356
11.

Reversible Opening of Intercellular Junctions of Intestinal Epithelial and Brain Endothelial Cells With Tight Junction Modulator Peptides.

Bocsik A, Walter FR, Gyebrovszki A, Fülöp L, Blasig I, Dabrowski S, Ötvös F, Tóth A, Rákhely G, Veszelka S, Vastag M, Szabó-Révész P, Deli MA.

J Pharm Sci. 2016 Feb;105(2):754-765. doi: 10.1016/j.xphs.2015.11.018.

PMID:
26869428
12.

New small-size peptides modulators of the exosite of BACE1 obtained from a structure-based design.

Gutierrez LJ, Angelina E, Gyebrovszki A, Fülöp L, Peruchena N, Baldoni HA, Penke B, Enriz RD.

J Biomol Struct Dyn. 2017 Feb;35(2):413-426. doi: 10.1080/07391102.2016.1145143. Epub 2016 Mar 8.

PMID:
26813690
13.

Protein Folding and Misfolding, Endoplasmic Reticulum Stress in Neurodegenerative Diseases: in Trace of Novel Drug Targets.

Penke B, Bogár F, Fülöp L.

Curr Protein Pept Sci. 2016;17(2):169-82. Review.

PMID:
26521955
14.

Amyloid-like Fibril Formation by Trypsin in Aqueous Ethanol. Inhibition of Fibrillation by PEG.

Kotormán M, Simon ML, Borics A, Szabó MR, Szabó K, Szögi T, Fülöp L.

Protein Pept Lett. 2015;22(12):1104-10.

PMID:
26428300
15.

Acute intracerebral treatment with amyloid-beta (1-42) alters the profile of neuronal oscillations that accompany LTP induction and results in impaired LTP in freely behaving rats.

Kalweit AN, Yang H, Colitti-Klausnitzer J, Fülöp L, Bozsó Z, Penke B, Manahan-Vaughan D.

Front Behav Neurosci. 2015 May 6;9:103. doi: 10.3389/fnbeh.2015.00103. eCollection 2015.

16.

Amyloid-β1-42 Disrupts Synaptic Plasticity by Altering Glutamate Recycling at the Synapse.

Varga E, Juhász G, Bozsó Z, Penke B, Fülöp L, Szegedi V.

J Alzheimers Dis. 2015;45(2):449-56. doi: 10.3233/JAD-142367.

PMID:
25547631
17.

Abeta(1-42) enhances neuronal excitability in the CA1 via NR2B subunit-containing NMDA receptors.

Varga E, Juhász G, Bozsó Z, Penke B, Fülöp L, Szegedi V.

Neural Plast. 2014;2014:584314. doi: 10.1155/2014/584314. Epub 2014 Sep 3.

18.

IKKβ deficiency in myeloid cells ameliorates Alzheimer's disease-related symptoms and pathology.

Liu Y, Liu X, Hao W, Decker Y, Schomburg R, Fülöp L, Pasparakis M, Menger MD, Fassbender K.

J Neurosci. 2014 Sep 24;34(39):12982-99. doi: 10.1523/JNEUROSCI.1348-14.2014.

19.

Simultaneous changes of spatial memory and spine density after intrahippocampal administration of fibrillar aβ1-42 to the rat brain.

Borbély E, Horváth J, Furdan S, Bozsó Z, Penke B, Fülöp L.

Biomed Res Int. 2014;2014:345305. doi: 10.1155/2014/345305. Epub 2014 Jun 23.

20.

Exploiting aromatic interactions for β-peptide foldamer helix stabilization: a significant design element.

Mándity IM, Monsignori A, Fülöp L, Forró E, Fülöp F.

Chemistry. 2014 Apr 14;20(16):4591-7. doi: 10.1002/chem.201304448. Epub 2014 Mar 24.

PMID:
24664416

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