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Items: 1 to 20 of 136

1.

A 13-week subchronic toxicity study of hexyl acetate in SD rats.

Toyoda T, Cho YM, Matsushita K, Tachibana S, Senuma M, Akagi JI, Ogawa K.

J Toxicol Pathol. 2019 Jul;32(3):205-212. doi: 10.1293/tox.2019-0002. Epub 2019 Mar 29.

2.

A 13-week subchronic toxicity study of vanillin propylene glycol acetal in F344 rats.

Matsushita K, Toyoda T, Morikawa T, Ogawa K.

Food Chem Toxicol. 2019 Oct;132:110643. doi: 10.1016/j.fct.2019.110643. Epub 2019 Jun 26.

PMID:
31252024
3.

Dimethylarsinic acid may promote prostate carcinogenesis in rats.

Suzuki S, Toyoda T, Kato H, Naiki-Ito A, Yamashita Y, Akagi JI, Cho YM, Ogawa K, Takahashi S.

J Toxicol Pathol. 2019 Apr;32(2):73-77. doi: 10.1293/tox.2018-0050. Epub 2018 Dec 21.

4.

DNA modifications that do not cause gene mutations confer the potential for mutagenicity by combined treatment with food chemicals.

Ishii Y, Yokoo Y, Kijima A, Takasu S, Ogawa K, Umemura T.

Food Chem Toxicol. 2019 Jul;129:144-152. doi: 10.1016/j.fct.2019.04.011. Epub 2019 Apr 25.

PMID:
31029721
5.

Effects of inhibition of hepatic sulfotransferase activity on renal genotoxicity induced by lucidin-3-O-primeveroside.

Ishii Y, Kijima A, Takasu S, Ogawa K, Umemura T.

J Appl Toxicol. 2019 Apr;39(4):650-657. doi: 10.1002/jat.3755. Epub 2018 Dec 12.

PMID:
30874336
6.

Twist1 was detected in mesenchymal cells of mammary fibroadenoma and invasive components of breast carcinoma in rats.

Funahashi S, Okazaki Y, Nagai H, Chew SH, Ogawa K, Toyoda T, Cho YM, Toyokuni S.

J Toxicol Pathol. 2019 Jan;32(1):19-26. doi: 10.1293/tox.2018-0029. Epub 2018 Sep 1.

7.

4-Methylthio-3-butenyl isothiocyanate (MTBITC) induced apoptotic cell death and G2/M cell cycle arrest via ROS production in human esophageal epithelial cancer cells.

Hirata T, Cho YM, Suzuki I, Toyoda T, Akagi JI, Nakamura Y, Numazawa S, Ogawa K.

J Toxicol Sci. 2019;44(2):73-81. doi: 10.2131/jts.44.73.

8.

Immunohistochemistry of γ-H2AX as a method of early detection of urinary bladder carcinogenicity in mice.

Sone M, Toyoda T, Cho YM, Akagi JI, Matsushita K, Mizuta Y, Morikawa T, Nishikawa A, Ogawa K.

J Appl Toxicol. 2019 Jun;39(6):868-876. doi: 10.1002/jat.3775. Epub 2019 Jan 31.

PMID:
30701581
9.

Distinct differences in the mechanisms of mucosal damage and γ-H2AX formation in the rat urinary bladder treated with o-toluidine and o-anisidine.

Toyoda T, Matsushita K, Morikawa T, Yamada T, Miyoshi N, Ogawa K.

Arch Toxicol. 2019 Mar;93(3):753-762. doi: 10.1007/s00204-019-02396-8. Epub 2019 Jan 17.

PMID:
30656379
10.

Molecular Pathological Differences in Global Gene Expression between Two Sustained Proliferative Lesions, Nodular Regenerative Hepatocellular Hyperplasia and Hepatocellular Adenoma, in Mice.

Takasu S, Yokoo Y, Ishii Y, Kijima A, Ogawa K, Umemura T.

Toxicol Pathol. 2019 Jan;47(1):44-52. doi: 10.1177/0192623318810200. Epub 2018 Dec 20.

PMID:
30572783
11.

Subchronic toxicity evaluation of isoeugenyl methyl ether in F344/DuCrj rats by 13-week oral administration.

Akagi JI, Cho YM, Mizuta Y, Tatebe C, Sato K, Ogawa K.

Regul Toxicol Pharmacol. 2019 Mar;102:34-39. doi: 10.1016/j.yrtph.2018.12.001. Epub 2018 Dec 5.

PMID:
30529462
12.

A 13-week subchronic toxicity study of 2-ethylbutanal in F344 rats.

Matsushita K, Toyoda T, Morikawa T, Takahashi M, Inoue K, Ogawa K.

Regul Toxicol Pharmacol. 2018 Dec;100:118-126. doi: 10.1016/j.yrtph.2018.10.012. Epub 2018 Oct 22.

PMID:
30359703
13.

Subchronic toxicity evaluation of 5-hexenyl isothiocyanate, a nature identical flavoring substance from Wasabia japonica, in F344/DuCrj rats.

Akagi JI, Cho YM, Mizuta Y, Toyoda T, Ogawa K.

Food Chem Toxicol. 2018 Dec;122:80-86. doi: 10.1016/j.fct.2018.09.060. Epub 2018 Sep 25.

PMID:
30266315
14.

Using RNA-Seq with 11 marker genes to evaluate 1,4-dioxane compared with typical genotoxic and non-genotoxic rat hepatocarcinogens.

Furihata C, Toyoda T, Ogawa K, Suzuki T.

Mutat Res Genet Toxicol Environ Mutagen. 2018 Oct;834:51-55. doi: 10.1016/j.mrgentox.2018.07.002. Epub 2018 Aug 17.

PMID:
30173864
15.

A 13-week subchronic toxicity study of acetaminophen using an obese rat model.

Toyoda T, Cho YM, Akagi JI, Mizuta Y, Matsushita K, Nishikawa A, Imaida K, Ogawa K.

J Toxicol Sci. 2018;43(7):423-433. doi: 10.2131/jts.43.423.

16.

Mechanisms Underlying Exacerbation of Osmotic Nephrosis Caused by Pre-existing Kidney Injury.

Matsushita K, Takasu S, Kuroda K, Ishii Y, Kijima A, Ogawa K, Umemura T.

Toxicol Sci. 2018 Oct 1;165(2):420-430. doi: 10.1093/toxsci/kfy151.

PMID:
29947792
17.

Size-dependent acute toxicity of silver nanoparticles in mice.

Cho YM, Mizuta Y, Akagi JI, Toyoda T, Sone M, Ogawa K.

J Toxicol Pathol. 2018 Jan;31(1):73-80. doi: 10.1293/tox.2017-0043. Epub 2017 Nov 19.

18.

Methods for the analysis of organophosphorus flame retardants-Comparison of GC-EI-MS, GC-NCI-MS, LC-ESI-MS/MS, and LC-APCI-MS/MS.

Tokumura M, Miyake Y, Wang Q, Nakayama H, Amagai T, Ogo S, Kume K, Kobayashi T, Takasu S, Ogawa K.

J Environ Sci Health A Tox Hazard Subst Environ Eng. 2018 Apr 16;53(5):475-481. doi: 10.1080/10934529.2017.1410419. Epub 2018 Jan 5.

PMID:
29303426
19.

Hypersensitivity of mouse embryonic fibroblast cells defective for DNA polymerases η, ι and κ to various genotoxic compounds: Its potential for application in chemical genotoxic screening.

Akagi J, Yokoi M, Cho YM, Toyoda T, Ohmori H, Hanaoka F, Ogawa K.

DNA Repair (Amst). 2018 Jan;61:76-85. doi: 10.1016/j.dnarep.2017.11.006. Epub 2017 Nov 26.

20.

Proof of concept testing of a positive reference material for in vivo and in vitro skin irritation testing.

Nomura Y, Lee M, Fukui C, Watanabe K, Olsen D, Turley A, Morishita Y, Kawakami T, Yuba T, Fujimaki H, Inoue K, Yoshida M, Ogawa K, Haishima Y.

J Biomed Mater Res B Appl Biomater. 2018 Nov;106(8):2807-2814. doi: 10.1002/jbm.b.34061. Epub 2017 Dec 11.

PMID:
29226582

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