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Items: 1 to 20 of 129

1.

A Comprehensive Review on Current Advances in Peptide Drug Development and Design.

Lee AC, Harris JL, Khanna KK, Hong JH.

Int J Mol Sci. 2019 May 14;20(10). pii: E2383. doi: 10.3390/ijms20102383. Review.

2.

Therapeutic cooperation between auranofin, a thioredoxin reductase inhibitor and anti-PD-L1 antibody for treatment of triple-negative breast cancer.

Raninga PV, Lee AC, Sinha D, Shih YY, Mittal D, Makhale A, Bain AL, Nanayakarra D, Tonissen KF, Kalimutho M, Khanna KK.

Int J Cancer. 2019 May 15. doi: 10.1002/ijc.32410. [Epub ahead of print]

PMID:
31090219
3.

Mechanisms of Genomic Instability in Breast Cancer.

Duijf PHG, Nanayakkara D, Nones K, Srihari S, Kalimutho M, Khanna KK.

Trends Mol Med. 2019 May 8. pii: S1471-4914(19)30090-5. doi: 10.1016/j.molmed.2019.04.004. [Epub ahead of print] Review.

PMID:
31078431
4.

MYB regulates the DNA damage response and components of the homology-directed repair pathway in human estrogen receptor-positive breast cancer cells.

Yang RM, Nanayakkara D, Kalimutho M, Mitra P, Khanna KK, Dray E, Gonda TJ.

Oncogene. 2019 Apr 10. doi: 10.1038/s41388-019-0789-3. [Epub ahead of print]

PMID:
30971760
5.

Blockade of PDGFRβ circumvents resistance to MEK-JAK inhibition via intratumoral CD8+ T-cells infiltration in triple-negative breast cancer.

Kalimutho M, Sinha D, Mittal D, Srihari S, Nanayakkara D, Shafique S, Raninga P, Nag P, Parsons K, Khanna KK.

J Exp Clin Cancer Res. 2019 Feb 18;38(1):85. doi: 10.1186/s13046-019-1075-5.

6.

RAD51 paralogs promote genomic integrity and chemoresistance in cancer by facilitating homologous recombination.

Harris JL, Rabellino A, Khanna KK.

Ann Transl Med. 2018 Dec;6(Suppl 2):S122. doi: 10.21037/atm.2018.12.30. No abstract available.

7.

Patterns of Genomic Instability in Breast Cancer.

Kalimutho M, Nones K, Srihari S, Duijf PHG, Waddell N, Khanna KK.

Trends Pharmacol Sci. 2019 Mar;40(3):198-211. doi: 10.1016/j.tips.2019.01.005. Epub 2019 Feb 6. Review.

PMID:
30736983
8.

Mitotic slippage: an old tale with a new twist.

Sinha D, Duijf PHG, Khanna KK.

Cell Cycle. 2019 Jan;18(1):7-15. doi: 10.1080/15384101.2018.1559557. Epub 2019 Jan 2.

PMID:
30601084
9.

Optimizing poly (ADP-ribose) polymerase inhibition through combined epigenetic and immunotherapy.

Prasanna T, Wu F, Khanna KK, Yip D, Malik L, Dahlstrom JE, Rao S.

Cancer Sci. 2018 Nov;109(11):3383-3392. doi: 10.1111/cas.13799. Epub 2018 Oct 20. Review.

10.

Serendipity, luck and hard work.

Khanna KK.

Nat Cell Biol. 2018 Sep;20(9):1004. doi: 10.1038/s41556-018-0170-8. No abstract available.

PMID:
30154556
11.

CEP55 is a determinant of cell fate during perturbed mitosis in breast cancer.

Kalimutho M, Sinha D, Jeffery J, Nones K, Srihari S, Fernando WC, Duijf PH, Vennin C, Raninga P, Nanayakkara D, Mittal D, Saunus JM, Lakhani SR, López JA, Spring KJ, Timpson P, Gabrielli B, Waddell N, Khanna KK.

EMBO Mol Med. 2018 Sep;10(9). pii: e8566. doi: 10.15252/emmm.201708566.

12.

Cep55 overexpression causes male-specific sterility in mice by suppressing Foxo1 nuclear retention through sustained activation of PI3K/Akt signaling.

Sinha D, Kalimutho M, Bowles J, Chan AL, Merriner DJ, Bain AL, Simmons JL, Freire R, Lopez JA, Hobbs RM, O'Bryan MK, Khanna KK.

FASEB J. 2018 Sep;32(9):4984-4999. doi: 10.1096/fj.201701096RR. Epub 2018 Apr 17.

PMID:
29683733
13.

The breast cancer antigen 5T4 interacts with Rab11, and is a target and regulator of Rab11 mediated trafficking.

Harris JL, Dave K, Gorman J, Khanna KK.

Int J Biochem Cell Biol. 2018 Jun;99:28-37. doi: 10.1016/j.biocel.2018.03.002. Epub 2018 Mar 13.

PMID:
29549047
14.

Characterization of a novel breast cancer cell line derived from a metastatic bone lesion of a breast cancer patient.

Johnson J, Bessette DC, Saunus JM, Smart CE, Song S, Johnston RL, Cocciardi S, Rozali EN, Johnstone CN, Vargas AC, Kazakoff SH, BioBank VC, Khanna KK, Lakhani SR, Chenevix-Trench G, Simpson PT, Nones K, Waddell N, Al-Ejeh F.

Breast Cancer Res Treat. 2018 Jul;170(1):179-188. doi: 10.1007/s10549-018-4719-9. Epub 2018 Feb 21.

PMID:
29468485
15.

Differentiation of Human Induced Pluripotent or Embryonic Stem Cells Decreases the DNA Damage Repair by Homologous Recombination.

Mujoo K, Pandita RK, Tiwari A, Charaka V, Chakraborty S, Singh DK, Hambarde S, Hittelman WN, Horikoshi N, Hunt CR, Khanna KK, Kots AY, Butler EB, Murad F, Pandita TK.

Stem Cell Reports. 2017 Nov 14;9(5):1660-1674. doi: 10.1016/j.stemcr.2017.10.002. Epub 2017 Nov 2.

16.

Corrigendum: Whole-genome landscape of pancreatic neuroendocrine tumours.

Scarpa A, Chang DK, Nones K, Corbo V, Patch AM, Bailey P, Lawlor RT, Johns AL, Miller DK, Mafficini A, Rusev B, Scardoni M, Antonello D, Barbi S, Sikora KO, Cingarlini S, Vicentini C, McKay S, Quinn MCJ, Bruxner TJC, Christ AN, Harliwong I, Idrisoglu S, McLean S, Nourse C, Nourbakhsh E, Wilson PJ, Anderson MJ, Fink JL, Newell F, Waddell N, Holmes O, Kazakoff SH, Leonard C, Wood S, Xu Q, Hiriyur Nagaraj S, Amato E, Dalai I, Bersani S, Cataldo I, Dei Tos AP, Capelli P, Vittoria Davì M, Landoni L, Malpaga A, Miotto M, Whitehall VLJ, Leggett BA, Harris JL, Harris J, Jones MD, Humphris J, Chantrill LA, Chin V, Nagrial AM, Pajic M, Scarlett CJ, Pinho A, Rooman I, Toon C, Wu J, Pinese M, Cowley M, Barbour A, Mawson A, Humphrey ES, Colvin EK, Chou A, Lovell JA, Jamieson NB, Duthie F, Gingras MC, Fisher WE, Dagg RA, Lau LMS, Lee M, Pickett HA, Reddel RR, Samra JS, Kench JG, Merrett ND, Epari K, Nguyen NQ, Zeps N, Falconi M, Simbolo M, Butturini G, Van Buren G, Partelli S, Fassan M; Australian Pancreatic Cancer Genome Initiative, Khanna KK, Gill AJ, Wheeler DA, Gibbs RA, Musgrove EA, Bassi C, Tortora G, Pederzoli P, Pearson JV, Waddell N, Biankin AV, Grimmond SM.

Nature. 2017 Oct 26;550(7677):548. doi: 10.1038/nature24026. Epub 2017 Sep 27.

PMID:
28953865
17.

Multidimensional phenotyping of breast cancer cell lines to guide preclinical research.

Saunus JM, Smart CE, Kutasovic JR, Johnston RL, Kalita-de Croft P, Miranda M, Rozali EN, Vargas AC, Reid LE, Lorsy E, Cocciardi S, Seidens T, McCart Reed AE, Dalley AJ, Wockner LF, Johnson J, Sarkar D, Askarian-Amiri ME, Simpson PT, Khanna KK, Chenevix-Trench G, Al-Ejeh F, Lakhani SR.

Breast Cancer Res Treat. 2018 Jan;167(1):289-301. doi: 10.1007/s10549-017-4496-x. Epub 2017 Sep 9.

PMID:
28889351
18.

Signaling to the Epigenome: New Insights into the Roles of Nuclear Signaling Kinases in the Context of the Immune System and Cancer.

Lim PS, Khanna KK, Rao S.

Front Immunol. 2017 Aug 21;8:980. doi: 10.3389/fimmu.2017.00980. eCollection 2017. No abstract available.

19.

Panel sequencing of 264 candidate susceptibility genes and segregation analysis in a cohort of non-BRCA1, non-BRCA2 breast cancer families.

Li J, Li H, Makunin I; kConFab Investigators, Thompson BA, Tao K, Young EL, Lopez J, Camp NJ, Tavtigian SV, John EM, Andrulis IL, Khanna KK, Goldgar D, Chenevix-Trench G.

Breast Cancer Res Treat. 2017 Dec;166(3):937-949. doi: 10.1007/s10549-017-4469-0. Epub 2017 Aug 24.

20.

Long Noncoding RNAs CUPID1 and CUPID2 Mediate Breast Cancer Risk at 11q13 by Modulating the Response to DNA Damage.

Betts JA, Moradi Marjaneh M, Al-Ejeh F, Lim YC, Shi W, Sivakumaran H, Tropée R, Patch AM, Clark MB, Bartonicek N, Wiegmans AP, Hillman KM, Kaufmann S, Bain AL, Gloss BS, Crawford J, Kazakoff S, Wani S, Wen SW, Day B, Möller A, Cloonan N, Pearson J, Brown MA, Mercer TR, Waddell N, Khanna KK, Dray E, Dinger ME, Edwards SL, French JD.

Am J Hum Genet. 2017 Aug 3;101(2):255-266. doi: 10.1016/j.ajhg.2017.07.007.

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