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Items: 1 to 20 of 84


Altering Antibiotic Regimen as Additional Control Measure in Suspected Multi-Drug-Resistant Enterobacter cloacae Outbreak in a Neonatal Intensive Care Unit.

Eichel V, Papan C, Boutin S, Pöschl J, Heeg K, Nurjadi D.

J Hosp Infect. 2019 Sep 13. pii: S0195-6701(19)30388-3. doi: 10.1016/j.jhin.2019.09.007. [Epub ahead of print]


Molecular characterization of carbapenem-resistant Acinetobacter baumannii using WGS revealed missed transmission events in Germany from 2012-15.

Eigenbrod T, Reuter S, Gross A, Kocer K, Günther F, Zimmermann S, Heeg K, Mutters NT, Nurjadi D.

J Antimicrob Chemother. 2019 Aug 31. pii: dkz360. doi: 10.1093/jac/dkz360. [Epub ahead of print]


Streptococcal Pyrogenic Exotoxin A-Stimulated Monocytes Mediate Regulatory T-Cell Accumulation through PD-L1 and Kynurenine.

Giesbrecht K, Förmer S, Sähr A, Heeg K, Hildebrand D.

Int J Mol Sci. 2019 Aug 13;20(16). pii: E3933. doi: 10.3390/ijms20163933.


Host-Derived Delta-Like Canonical Notch Ligand 1 as a Novel Diagnostic Biomarker for Bacterial Sepsis-Results From a Combinational Secondary Analysis.

Hildebrand D, Decker SO, Koch C, Schmitt FCF, Ruhrmann S, Schneck E, Sander M, Weigand MA, Brenner T, Heeg K, Uhle F.

Front Cell Infect Microbiol. 2019 Jul 23;9:267. doi: 10.3389/fcimb.2019.00267. eCollection 2019.


Silencing SOCS1 via Liposome-Packed siRNA Sustains TLR4-Ligand Adjuvant.

Hildebrand D, Metz-Zumaran C, Jaschkowitz G, Heeg K.

Front Immunol. 2019 Jun 4;10:1279. doi: 10.3389/fimmu.2019.01279. eCollection 2019.


Increase in the prevalence of Panton-Valentine leukocidin and clonal shift in community-onset methicillin-resistant Staphylococcus aureus causing skin and soft-tissue infections in the Rhine-Neckar Region, Germany, 2012-2016.

Klein S, Menz MD, Zanger P, Heeg K, Nurjadi D.

Int J Antimicrob Agents. 2019 Mar;53(3):261-267. doi: 10.1016/j.ijantimicag.2018.10.026. Epub 2018 Nov 6.


The Interplay of Notch Signaling and STAT3 in TLR-Activated Human Primary Monocytes.

Hildebrand D, Uhle F, Sahin D, Krauser U, Weigand MA, Heeg K.

Front Cell Infect Microbiol. 2018 Jul 10;8:241. doi: 10.3389/fcimb.2018.00241. eCollection 2018.


Hsa-miR-99b/let-7e/miR-125a Cluster Regulates Pathogen Recognition Receptor-Stimulated Suppressive Antigen-Presenting Cells.

Hildebrand D, Eberle ME, Wölfle SM, Egler F, Sahin D, Sähr A, Bode KA, Heeg K.

Front Immunol. 2018 Jun 18;9:1224. doi: 10.3389/fimmu.2018.01224. eCollection 2018.


Cross-specificity of protective human antibodies against Klebsiella pneumoniae LPS O-antigen.

Rollenske T, Szijarto V, Lukasiewicz J, Guachalla LM, Stojkovic K, Hartl K, Stulik L, Kocher S, Lasitschka F, Al-Saeedi M, Schröder-Braunstein J, von Frankenberg M, Gaebelein G, Hoffmann P, Klein S, Heeg K, Nagy E, Nagy G, Wardemann H.

Nat Immunol. 2018 Jun;19(6):617-624. doi: 10.1038/s41590-018-0106-2. Epub 2018 May 14.


Draft Genome Sequence of Staphylococcus aureus Strain HD1410, Isolated from a Persistent Nasal Carrier.

Nurjadi D, Boutin S, Dalpke A, Heeg K, Zanger P.

Genome Announc. 2018 May 10;6(19). pii: e00411-18. doi: 10.1128/genomeA.00411-18.


Significant increase in cultivation of Gardnerella vaginalis, Alloscardovia omnicolens, Actinotignum schaalii, and Actinomyces spp. in urine samples with total laboratory automation.

Klein S, Nurjadi D, Horner S, Heeg K, Zimmermann S, Burckhardt I.

Eur J Clin Microbiol Infect Dis. 2018 Jul;37(7):1305-1311. doi: 10.1007/s10096-018-3250-6. Epub 2018 Apr 13.


A Trial of Antibiotics for Smaller Skin Abscesses.

Nurjadi D, Heeg K, Zanger P; Staph Trav Network.

N Engl J Med. 2017 Dec 28;377(26):e36. doi: 10.1056/NEJMc1711124. No abstract available.


IL-1β As Mediator of Resolution That Reprograms Human Peripheral Monocytes toward a Suppressive Phenotype.

Giesbrecht K, Eberle ME, Wölfle SJ, Sahin D, Sähr A, Oberhardt V, Menne Z, Bode KA, Heeg K, Hildebrand D.

Front Immunol. 2017 Aug 3;8:899. doi: 10.3389/fimmu.2017.00899. eCollection 2017.


Transmission of ST8-USA300 Latin American Variant Methicillin-Resistant Staphylococcus aureus on a Neonatal Intensive Care Unit: Recurrent Skin and Soft- Tissue Infections as a Marker for Epidemic Community-Associated-MRSA Colonization.

Nurjadi D, Klein S, Zimmermann S, Heeg K, Zanger P.

Infect Control Hosp Epidemiol. 2017 Jul;38(7):883-885. doi: 10.1017/ice.2017.88. Epub 2017 May 18. No abstract available.


Improvement of infection control management by routine molecular evaluation of pathogen clusters.

Mutters NT, Heeg K, Späth I, Henny N, Günther F.

Diagn Microbiol Infect Dis. 2017 May;88(1):82-87. doi: 10.1016/j.diagmicrobio.2017.01.013. Epub 2017 Jan 26.


Ratio of T-Helper Type 1 (Th1) to Th17 Cytokines in Whole Blood Is Associated With Human β-Defensin 3 Expression in Skin and Persistent Staphylococcus aureus Nasal Carriage.

Nurjadi D, Kain M, Marcinek P, Gaile M, Heeg K, Zanger P.

J Infect Dis. 2016 Dec 1;214(11):1744-1751. Epub 2016 Sep 19.


Pasteurella multocida Toxin Manipulates T Cell Differentiation.

Hildebrand D, Heeg K, Kubatzky KF.

Front Microbiol. 2015 Nov 19;6:1273. doi: 10.3389/fmicb.2015.01273. eCollection 2015.


T-cell activation or tolerization: the Yin and Yang of bacterial superantigens.

Sähr A, Förmer S, Hildebrand D, Heeg K.

Front Microbiol. 2015 Oct 20;6:1153. doi: 10.3389/fmicb.2015.01153. eCollection 2015.


Inhibition of Histone Deacetylases Permits Lipopolysaccharide-Mediated Secretion of Bioactive IL-1β via a Caspase-1-Independent Mechanism.

Stammler D, Eigenbrod T, Menz S, Frick JS, Sweet MJ, Shakespear MR, Jantsch J, Siegert I, Wölfle S, Langer JD, Oehme I, Schaefer L, Fischer A, Knievel J, Heeg K, Dalpke AH, Bode KA.

J Immunol. 2015 Dec 1;195(11):5421-31. doi: 10.4049/jimmunol.1501195. Epub 2015 Oct 30.


Contributing and Terminating Factors of a Large RSV Outbreak in an Adult Hematology and Transplant Unit.

RSV Outbreak Investigation Team; RSV Outbreak Investigation Team.

PLoS Curr. 2014 Sep 19;6. pii: ecurrents.outbreaks.3bc85b2a508d205ecc4a5534ecb1f9be. doi: 10.1371/currents.outbreaks.3bc85b2a508d205ecc4a5534ecb1f9be. Erratum in: PLoS Curr. 2017 Feb 27;9:.

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