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Items: 1 to 20 of 34


Conditional KCa3.1-transgene induction in murine skin produces pruritic eczematous dermatitis with severe epidermal hyperplasia and hyperkeratosis.

Lozano-Gerona J, Oliván-Viguera A, Delgado-Wicke P, Singh V, Brown BM, Tapia-Casellas E, Pueyo E, Valero MS, Garcia-Otín ÁL, Giraldo P, Abarca-Lachen E, Surra JC, Osada J, Hamilton KL, Raychaudhuri SP, Marigil M, Juarranz Á, Wulff H, Miura H, Gilaberte Y, Köhler R.

PLoS One. 2020 Mar 9;15(3):e0222619. doi: 10.1371/journal.pone.0222619. eCollection 2020.


KCa3.1 Transgene Induction in Murine Intestinal Epithelium Causes Duodenal Chyme Accumulation and Impairs Duodenal Contractility.

Valero MS, Ramón-Gimenez M, Lozano-Gerona J, Delgado-Wicke P, Calmarza P, Oliván-Viguera A, López V, Garcia-Otín ÁL, Valero S, Pueyo E, Hamilton KL, Miura H, Köhler R.

Int J Mol Sci. 2019 Mar 8;20(5). pii: E1193. doi: 10.3390/ijms20051193.


Plasma membrane insertion of KCa2.3 (SK3) is dependent upon the SNARE proteins, syntaxin-4 and SNAP23.

Bertuccio CA, Wang TT, Hamilton KL, Rodriguez-Gil DJ, Condliffe SB, Devor DC.

PLoS One. 2018 May 16;13(5):e0196717. doi: 10.1371/journal.pone.0196717. eCollection 2018.


Pharmacological activation of TRPV4 produces immediate cell damage and induction of apoptosis in human melanoma cells and HaCaT keratinocytes.

Olivan-Viguera A, Garcia-Otin AL, Lozano-Gerona J, Abarca-Lachen E, Garcia-Malinis AJ, Hamilton KL, Gilaberte Y, Pueyo E, Köhler R.

PLoS One. 2018 Jan 2;13(1):e0190307. doi: 10.1371/journal.pone.0190307. eCollection 2018.


AJP-Cell Physiology begins landmark reviews in cell physiology: an editorial from the senior editors of AJP-Cell Physiology.

Delpire E, Hamilton KL, Hawke TJ, Isenberg JS, Lotersztajn S, Yuan JX, Adams JC.

Am J Physiol Cell Physiol. 2018 Jan 1;314(1):C1-C2. doi: 10.1152/ajpcell.00256.2017. Epub 2017 Nov 14. No abstract available.


Modulation of Retrograde Trafficking of KCa3.1 in a Polarized Epithelium.

Lee BS, Devor DC, Hamilton KL.

Front Physiol. 2017 Jul 18;8:489. doi: 10.3389/fphys.2017.00489. eCollection 2017.


The Role of the Cytoskeleton and Myosin-Vc in the Targeting of KCa3.1 to the Basolateral Membrane of Polarized Epithelial Cells.

Farquhar RE, Rodrigues E, Hamilton KL.

Front Physiol. 2017 Jan 4;7:639. doi: 10.3389/fphys.2016.00639. eCollection 2016.


50 Years of renal physiology from one man and the perfused tubule: Maurice B. Burg.

Hamilton KL, Moore AB.

Am J Physiol Renal Physiol. 2016 Aug 1;311(2):F291-304. doi: 10.1152/ajprenal.00198.2016. Epub 2016 Apr 27.


New life in overactive bladder. Focus on "Novel regulatory mechanism in human urinary bladder: central role of transient receptor potential melastatin 4 channels in detrusor smooth muscle function".

Hamilton KL.

Am J Physiol Cell Physiol. 2016 Apr 1;310(7):C597-9. doi: 10.1152/ajpcell.00039.2016. Epub 2016 Feb 17. No abstract available.


The Role of MicroRNAs in the Regulation of K(+) Channels in Epithelial Tissue.

Pilmore E, Hamilton KL.

Front Physiol. 2015 Dec 1;6:352. doi: 10.3389/fphys.2015.00352. eCollection 2015. Review.


Cleavage: what's up with prostasin and ENaC these days?

Hamilton KL.

Am J Physiol Renal Physiol. 2014 Dec 1;307(11):F1196-7. doi: 10.1152/ajprenal.00522.2014. Epub 2014 Sep 24. No abstract available.


Distinct action of flavonoids, myricetin and quercetin, on epithelial Cl⁻ secretion: useful tools as regulators of Cl⁻ secretion.

Sun H, Niisato N, Nishio K, Hamilton KL, Marunaka Y.

Biomed Res Int. 2014;2014:902735. doi: 10.1155/2014/902735. Epub 2014 Apr 10.


Anterograde trafficking of KCa3.1 in polarized epithelia is Rab1- and Rab8-dependent and recycling endosome-independent.

Bertuccio CA, Lee SL, Wu G, Butterworth MB, Hamilton KL, Devor DC.

PLoS One. 2014 Mar 14;9(3):e92013. doi: 10.1371/journal.pone.0092013. eCollection 2014.


Even an old technique is suitable in the molecular world of science: the everted sac preparation turns 60 years old.

Hamilton KL.

Am J Physiol Cell Physiol. 2014 Apr 15;306(8):C715-20. doi: 10.1152/ajpcell.00041.2014. Epub 2014 Feb 26.


Glucose transport into everted sacs of the small intestine of mice.

Hamilton KL, Butt AG.

Adv Physiol Educ. 2013 Dec;37(4):415-26. doi: 10.1152/advan.00017.2013.


Cyclosporine A and lovastatin: the good and the bad, but who will be the winner?

Hamilton KL.

Am J Physiol Renal Physiol. 2013 Sep 1;305(5):F643-4. doi: 10.1152/ajprenal.00321.2013. Epub 2013 Jun 12. No abstract available.


Robert K. Crane-Na(+)-glucose cotransporter to cure?

Hamilton KL.

Front Physiol. 2013 Mar 22;4:53. doi: 10.3389/fphys.2013.00053. eCollection 2013.


Trafficking of intermediate (KCa3.1) and small (KCa2.x) conductance, Ca(2+)-activated K(+) channels: a novel target for medicinal chemistry efforts?

Balut CM, Hamilton KL, Devor DC.

ChemMedChem. 2012 Oct;7(10):1741-55. doi: 10.1002/cmdc.201200226. Epub 2012 Aug 7. Review.


βPix is a New Player in Renal Physiology.

Hamilton KL, Pao AC.

Front Physiol. 2012 Jul 20;3:268. doi: 10.3389/fphys.2012.00268. eCollection 2012. No abstract available.


A tool for multi-scale modelling of the renal nephron.

Nickerson DP, Terkildsen JR, Hamilton KL, Hunter PJ.

Interface Focus. 2011 Jun 6;1(3):417-25. doi: 10.1098/rsfs.2010.0032. Epub 2011 Mar 30.

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