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Items: 1 to 20 of 52

1.

Innate immune responses triggered by nucleic acids inspire the design of immunomodulatory nucleic acid nanoparticles (NANPs).

Chandler M, Johnson MB, Panigaj M, Afonin KA.

Curr Opin Biotechnol. 2019 Nov 25;63:8-15. doi: 10.1016/j.copbio.2019.10.011. [Epub ahead of print] Review.

PMID:
31778882
2.

Erratum: Hong, E., et al. Toll-Like Receptor-Mediated Recognition of Nucleic Acid Nanoparticles (NANPs) in Human Primary Blood Cells. Molecules 2019, 24, 1094.

Hong E, Halman JR, Shah A, Cedrone E, Truong N, Afonin KA, Dobrovolskaia MA.

Molecules. 2019 Oct 25;24(21). pii: E3852. doi: 10.3390/molecules24213852.

3.

A cationic amphiphilic co-polymer as a carrier of nucleic acid nanoparticles (Nanps) for controlled gene silencing, immunostimulation, and biodistribution.

Halman JR, Kim KT, Gwak SJ, Pace R, Johnson MB, Chandler MR, Rackley L, Viard M, Marriott I, Lee JS, Afonin KA.

Nanomedicine. 2019 Oct 25;23:102094. doi: 10.1016/j.nano.2019.102094. [Epub ahead of print]

PMID:
31669854
4.

Aptamers as Modular Components of Therapeutic Nucleic Acid Nanotechnology.

Panigaj M, Johnson MB, Ke W, McMillan J, Goncharova EA, Chandler M, Afonin KA.

ACS Nano. 2019 Nov 26;13(11):12301-12321. doi: 10.1021/acsnano.9b06522. Epub 2019 Nov 5.

PMID:
31664817
5.

Editorial for the Special Issue on "Nucleic Acid Architectures for Therapeutics, Diagnostics, Devices and Materials".

Halman JR, Afonin KA.

Nanomaterials (Basel). 2019 Jun 30;9(7). pii: E951. doi: 10.3390/nano9070951.

6.

RNA Fibers as Optimized Nanoscaffolds for siRNA Coordination and Reduced Immunological Recognition.

Rackley L, Stewart JM, Salotti J, Krokhotin A, Shah A, Halman JR, Juneja R, Smollett J, Lee L, Roark K, Viard M, Tarannum M, Vivero-Escoto J, Johnson PF, Dobrovolskaia MA, Dokholyan NV, Franco E, Afonin KA.

Adv Funct Mater. 2018 Nov 28;28(48). pii: 1805959. doi: 10.1002/adfm.201805959. Epub 2018 Oct 9.

7.

Small-Angle Scattering as a Structural Probe for Nucleic Acid Nanoparticles (NANPs) in a Dynamic Solution Environment.

Oliver RC, Rolband LA, Hutchinson-Lundy AM, Afonin KA, Krueger JK.

Nanomaterials (Basel). 2019 May 2;9(5). pii: E681. doi: 10.3390/nano9050681. Review.

8.

First Step Towards Larger DNA-Based Assemblies of Fluorescent Silver Nanoclusters: Template Design and Detailed Characterization of Optical Properties.

Yourston LE, Lushnikov AY, Shevchenko OA, Afonin KA, Krasnoslobodtsev AV.

Nanomaterials (Basel). 2019 Apr 13;9(4). pii: E613. doi: 10.3390/nano9040613.

9.

Smart-Responsive Nucleic Acid Nanoparticles (NANPs) with the Potential to Modulate Immune Behavior.

Chandler M, Afonin KA.

Nanomaterials (Basel). 2019 Apr 12;9(4). pii: E611. doi: 10.3390/nano9040611. Review.

10.

Toll-Like Receptor-Mediated Recognition of Nucleic Acid Nanoparticles (NANPs) in Human Primary Blood Cells.

Hong E, Halman JR, Shah A, Cedrone E, Truong N, Afonin KA, Dobrovolskaia MA.

Molecules. 2019 Mar 20;24(6). pii: E1094. doi: 10.3390/molecules24061094. Erratum in: Molecules. 2019 Oct 25;24(21):.

11.

Multimodal Polysilsesquioxane Nanoparticles for Combinatorial Therapy and Gene Delivery in Triple-Negative Breast Cancer.

Juneja R, Lyles Z, Vadarevu H, Afonin KA, Vivero-Escoto JL.

ACS Appl Mater Interfaces. 2019 Apr 3;11(13):12308-12320. doi: 10.1021/acsami.9b00704. Epub 2019 Mar 19.

PMID:
30844224
12.

RNA-DNA fibers and polygons with controlled immunorecognition activate RNAi, FRET and transcriptional regulation of NF-κB in human cells.

Ke W, Hong E, Saito RF, Rangel MC, Wang J, Viard M, Richardson M, Khisamutdinov EF, Panigaj M, Dokholyan NV, Chammas R, Dobrovolskaia MA, Afonin KA.

Nucleic Acids Res. 2019 Feb 20;47(3):1350-1361. doi: 10.1093/nar/gky1215.

13.

Broccoli Fluorets: Split Aptamers as a User-Friendly Fluorescent Toolkit for Dynamic RNA Nanotechnology.

Chandler M, Lyalina T, Halman J, Rackley L, Lee L, Dang D, Ke W, Sajja S, Woods S, Acharya S, Baumgarten E, Christopher J, Elshalia E, Hrebien G, Kublank K, Saleh S, Stallings B, Tafere M, Striplin C, Afonin KA.

Molecules. 2018 Dec 2;23(12). pii: E3178. doi: 10.3390/molecules23123178.

14.

Magnetic nanoparticles loaded with functional RNA nanoparticles.

Cruz-Acuña M, Halman JR, Afonin KA, Dobson J, Rinaldi C.

Nanoscale. 2018 Sep 27;10(37):17761-17770. doi: 10.1039/c8nr04254c.

PMID:
30215080
15.

Structure and Composition Define Immunorecognition of Nucleic Acid Nanoparticles.

Hong E, Halman JR, Shah AB, Khisamutdinov EF, Dobrovolskaia MA, Afonin KA.

Nano Lett. 2018 Jul 11;18(7):4309-4321. doi: 10.1021/acs.nanolett.8b01283. Epub 2018 Jun 20.

16.

Dynamic Behavior of RNA Nanoparticles Analyzed by AFM on a Mica/Air Interface.

Sajja S, Chandler M, Fedorov D, Kasprzak WK, Lushnikov A, Viard M, Shah A, Dang D, Dahl J, Worku B, Dobrovolskaia MA, Krasnoslobodtsev A, Shapiro BA, Afonin KA.

Langmuir. 2018 Dec 11;34(49):15099-15108. doi: 10.1021/acs.langmuir.8b00105. Epub 2018 Apr 30.

17.

Label-Free Single-Molecule Thermoscopy Using a Laser-Heated Nanopore.

Yamazaki H, Hu R, Henley RY, Halman J, Afonin KA, Yu D, Zhao Q, Wanunu M.

Nano Lett. 2017 Nov 8;17(11):7067-7074. doi: 10.1021/acs.nanolett.7b03752. Epub 2017 Oct 10.

PMID:
28975798
18.

Programmable Nucleic Acid Based Polygons with Controlled Neuroimmunomodulatory Properties for Predictive QSAR Modeling.

Johnson MB, Halman JR, Satterwhite E, Zakharov AV, Bui MN, Benkato K, Goldsworthy V, Kim T, Hong E, Dobrovolskaia MA, Khisamutdinov EF, Marriott I, Afonin KA.

Small. 2017 Nov;13(42). doi: 10.1002/smll.201701255. Epub 2017 Sep 18.

19.

Picomolar Fingerprinting of Nucleic Acid Nanoparticles Using Solid-State Nanopores.

Alibakhshi MA, Halman JR, Wilson J, Aksimentiev A, Afonin KA, Wanunu M.

ACS Nano. 2017 Oct 24;11(10):9701-9710. doi: 10.1021/acsnano.7b04923. Epub 2017 Sep 11.

20.

Preparation of a Conditional RNA Switch.

Zakrevsky P, Parlea L, Viard M, Bindewald E, Afonin KA, Shapiro BA.

Methods Mol Biol. 2017;1632:303-324. doi: 10.1007/978-1-4939-7138-1_20.

PMID:
28730448

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