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Items: 1 to 20 of 175

1.

High-throughput method to analyze tegafur and 5-fluorouracil in human tears and plasma using hydrophilic interaction liquid chromatography-tandem mass spectrometry.

Shiokawa R, Lee XP, Yamada M, Fujishiro M, Sakamaki H, Hasegawa C, Ishida H, Ikeda K, Fujita KI, Iwabuchi S, Onda H, Kumazawa T, Sasaki Y, Sato K, Matsuyama T.

Rapid Commun Mass Spectrom. 2019 Jul 19. doi: 10.1002/rcm.8531. [Epub ahead of print]

PMID:
31323696
2.

Rabeprazole intake does not affect systemic exposure to capecitabine and its metabolites, 5'-deoxy-5-fluorocytidine, 5'-deoxy-5-fluorouridine, and 5-fluorouracil.

Sekido M, Fujita KI, Kubota Y, Ishida H, Takahashi T, Ohkuma R, Tsunoda T, Ishikawa F, Shibanuma M, Sasaki Y.

Cancer Chemother Pharmacol. 2019 Jun;83(6):1127-1135. doi: 10.1007/s00280-019-03837-y. Epub 2019 Apr 9.

PMID:
30972456
3.

Pazopanib interacts with irinotecan by inhibiting UGT1A1-mediated glucuronidation, but not OATP1B1-mediated hepatic uptake, of an active metabolite SN-38.

Iwase M, Fujita KI, Nishimura Y, Seba N, Masuo Y, Ishida H, Kato Y, Kiuchi Y.

Cancer Chemother Pharmacol. 2019 May;83(5):993-998. doi: 10.1007/s00280-019-03784-8. Epub 2019 Feb 13.

PMID:
30810774
4.

Influx and Efflux Transporters Contribute to the Increased Dermal Exposure to Active Metabolite of Regorafenib After Repeated Oral Administration in Mice.

Al-Shammari AH, Masuo Y, Fujita KI, Yoshikawa Y, Nakamichi N, Kubota Y, Sasaki Y, Kato Y.

J Pharm Sci. 2019 Jun;108(6):2173-2179. doi: 10.1016/j.xphs.2019.01.018. Epub 2019 Jan 24.

PMID:
30685396
5.

Evaluation of Inhibitory Activities of UK-2A, an Antimycin-Type Antibiotic, and Its Synthetic Analogues against the Production of Anti-inflammatory Cytokine IL-4.

Usuki Y, Ishii S, Ijiri M, Yoshida KI, Satoh T, Horigome S, Yoshida I, Mishima T, Fujita KI.

J Nat Prod. 2018 Nov 26;81(11):2590-2594. doi: 10.1021/acs.jnatprod.8b00559. Epub 2018 Nov 12.

PMID:
30417645
6.

KRAS and EGFR Amplifications Mediate Resistance to Rociletinib and Osimertinib in Acquired Afatinib-Resistant NSCLC Harboring Exon 19 Deletion/T790M in EGFR.

Nakatani K, Yamaoka T, Ohba M, Fujita KI, Arata S, Kusumoto S, Taki-Takemoto I, Kamei D, Iwai S, Tsurutani J, Ohmori T.

Mol Cancer Ther. 2019 Jan;18(1):112-126. doi: 10.1158/1535-7163.MCT-18-0591. Epub 2018 Oct 15.

PMID:
30322949
7.

Coadministration of cytotoxic chemotherapeutic agents with irinotecan is a risk factor for irinotecan-induced cholinergic syndrome in Japanese patients with cancer.

Tsuboya A, Fujita KI, Kubota Y, Ishida H, Taki-Takemoto I, Kamei D, Iwai S, Sasaki Y.

Int J Clin Oncol. 2019 Feb;24(2):222-230. doi: 10.1007/s10147-018-1347-7. Epub 2018 Sep 22.

PMID:
30244364
8.

123I-iomazenil whole-body imaging to detect hepatic carboxylesterase drug-metabolizing enzyme activity.

Mizutani A, Kobayashi M, Fujita KI, Takahashi K, Hokama T, Takasu H, Nishi K, Nishii R, Shikano N, Fukuchi K, Kawai K.

Nucl Med Commun. 2018 Sep;39(9):825-833. doi: 10.1097/MNM.0000000000000875.

PMID:
29877992
9.

Effect of nagilactone E on cell morphology and glucan biosynthesis in budding yeast Saccharomyces cerevisiae.

Hayashi K, Yamaguchi Y, Ogita A, Tanaka T, Kubo I, Fujita KI.

Fitoterapia. 2018 Jul;128:112-117. doi: 10.1016/j.fitote.2018.05.003. Epub 2018 May 14.

PMID:
29772300
10.

Organic Cation Transporter 1 Is Responsible for Hepatocellular Uptake of the Tyrosine Kinase Inhibitor Pazopanib.

Ellawatty WEA, Masuo Y, Fujita KI, Yamazaki E, Ishida H, Arakawa H, Nakamichi N, Abdelwahed R, Sasaki Y, Kato Y.

Drug Metab Dispos. 2018 Jan;46(1):33-40. doi: 10.1124/dmd.117.076554. Epub 2017 Oct 31.

PMID:
29089306
11.

Reversible Interconversion between 2,5-Dimethylpyrazine and 2,5-Dimethylpiperazine by Iridium-Catalyzed Hydrogenation/Dehydrogenation for Efficient Hydrogen Storage.

Fujita KI, Wada T, Shiraishi T.

Angew Chem Int Ed Engl. 2017 Aug 28;56(36):10886-10889. doi: 10.1002/anie.201705452. Epub 2017 Jul 27.

PMID:
28748606
12.

Involvement of Irreversible Vacuolar Membrane Fragmentation in the Lethality of Food Emulsifier Diglycerol Monolaurate against Budding Yeast.

Ikegawa C, Ogita A, Doi T, Kumazawa F, Fujita KI, Tanaka T.

J Agric Food Chem. 2017 Jul 19;65(28):5650-5656. doi: 10.1021/acs.jafc.7b01580. Epub 2017 Jul 3.

PMID:
28671839
13.

Involvement of the Transporters P-Glycoprotein and Breast Cancer Resistance Protein in Dermal Distribution of the Multikinase Inhibitor Regorafenib and Its Active Metabolites.

Fujita KI, Masuo Y, Yamazaki E, Shibutani T, Kubota Y, Nakamichi N, Sasaki Y, Kato Y.

J Pharm Sci. 2017 Sep;106(9):2632-2641. doi: 10.1016/j.xphs.2017.04.064. Epub 2017 May 4.

PMID:
28479358
14.

Vacuolar H+-ATPase subunit Vma1p functions as the molecular ligand in the vacuole-targeting fungicidal activity of polymyxin B.

Iida M, Yamada K, Nango Y, Yamaguchi Y, Ogita A, Fujita KI, Tanaka T.

Microbiology. 2017 Apr;163(4):531-540. doi: 10.1099/mic.0.000450.

PMID:
28443813
15.

Toxicities of Receptor Tyrosine Kinase Inhibitors in Cancer Pharmacotherapy: Management with Clinical Pharmacology.

Fujita KI, Ishida H, Kubota Y, Sasaki Y.

Curr Drug Metab. 2017;18(3):186-198. doi: 10.2174/1389200218666170105165832. Review.

PMID:
28059038
16.

Cost-minimization analysis of adjuvant chemotherapy regimens given to patients with colorectal cancer in Japan.

Takata K, Fujita KI, Kubota Y, Ishida H, Ichikawa W, Shimada K, Sekikawa T, Taki-Takemoto I, Kamei D, Iwai S, Sasaki Y.

J Pharm Health Care Sci. 2016 Nov 9;2:30. eCollection 2016.

17.

Investigation of Bioequivalence Between Brand-name and Generic Irinotecan Products.

Saito KI, Inoue Y, Ikegami Y, Nanbo I, Onozuka M, Sano K, Yoshida H, Sakamoto T, Tatebayashi E, Fujita KI, Sasaki Y, Kitazawa T.

Anticancer Res. 2016 Nov;36(11):5957-5963.

PMID:
27793921
18.

Anethole potentiates dodecanol's fungicidal activity by reducing PDR5 expression in budding yeast.

Fujita KI, Ishikura T, Jono Y, Yamaguchi Y, Ogita A, Kubo I, Tanaka T.

Biochim Biophys Acta Gen Subj. 2017 Feb;1861(2):477-484. doi: 10.1016/j.bbagen.2016.09.010. Epub 2016 Sep 12.

PMID:
27632201
19.

Cytoskeletal impairment during isoamyl alcohol-induced cell elongation in budding yeast.

Murata W, Kinpara S, Kitahara N, Yamaguchi Y, Ogita A, Tanaka T, Fujita K.

Sci Rep. 2016 Aug 10;6:31127. doi: 10.1038/srep31127.

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