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Items: 1 to 20 of 243

1.

Carbapenem-resistant Klebsiella pneumoniae in a Febrile Neutropenia Patient With Acute Myelogenous Leukemia After Hematopoietic Stem Cell Transplantation.

Asai S, Ohshima T, Iwashita H, Ishii Y, Aoki K, Minakawa Y, Machida S, Umezawa K, Tateda K, Miyachi H.

Infect Dis Clin Pract (Baltim Md). 2018 Sep;26(5):e38-e39. doi: 10.1097/IPC.0000000000000633. Epub 2018 Apr 21. No abstract available.

PMID:
30245563
2.

Development of a sensitive immunochromatographic kit using fluorescent silica nanoparticles for rapid serodiagnosis of amebiasis.

Tachibana H, Kakino A, Kazama M, Feng M, Asai S, Umezawa K, Nozaki T, Makiuchi T, Kamada T, Watanabe H, Horiki N, Cheng X, Masuda G.

Parasitology. 2018 May 9:1-6. doi: 10.1017/S0031182018000690. [Epub ahead of print]

PMID:
29739480
3.

Corrigendum to "poly (ADP-ribose) polymerase inhibition synergizes with the NF-κB inhibitor DHMEQ to kill hepatocellular carcinoma cells" [Biochim. Biophys. Acta 1853(12)(2015) 3224-3234].

Lampiasi N, Umezawa K, Montalto G, Cervello M.

Biochim Biophys Acta Mol Cell Res. 2018 Jul;1865(7):1023. doi: 10.1016/j.bbamcr.2018.04.004. Epub 2018 Apr 21. No abstract available.

PMID:
29685431
4.

DTCM-glutarimide delays growth and radiosensitizes glioblastoma.

Roberto GM, Paiva HH, Botelho de Souza LE, Pezuk JA, Vieira GM, Francisco de Oliveira H, Umezawa K, Tone LG, Brassesco MS.

Anticancer Agents Med Chem. 2018 Apr 22. doi: 10.2174/1871520618666180423105740. [Epub ahead of print]

PMID:
29683097
5.

Inhibition of Late and Early Phases of Cancer Metastasis by the NF-κB Inhibitor DHMEQ Derived from Microbial Bioactive Metabolite Epoxyquinomicin: A Review.

Lin Y, Ukaji T, Koide N, Umezawa K.

Int J Mol Sci. 2018 Mar 3;19(3). pii: E729. doi: 10.3390/ijms19030729. Review.

6.

Therapeutic activity of plant-derived alkaloid conophylline on metabolic syndrome and neurodegenerative disease models.

Umezawa K, Kojima I, Simizu S, Lin Y, Fukatsu H, Koide N, Nakade Y, Yoneda M.

Hum Cell. 2018 Apr;31(2):95-101. doi: 10.1007/s13577-017-0196-4. Epub 2017 Dec 16. Review.

PMID:
29249016
7.

The Implementation of a Hospital-wide Practice for the Selective Use of Carbapenems Based on the Monitoring of Susceptibility of Pseudomonas aeruginosa Isolates.

Ohshima T, Asai S, Miyazawa M, Yamamoto Y, Hisada A, Kumazawa C, Hashimoto M, Fukawa K, Iwashita H, Umezawa K, Yamada S, Yamamoto Y, Miyachi H.

Tokai J Exp Clin Med. 2017 Dec 20;42(4):176-181.

8.

Antineoplastic Effects of NF-κB Inhibition by DHMEQ (Dehydroxymethylepoxyquinomicin) Alone and in Co-treatment with Radio-and Chemotherapy in Medulloblastoma Cell Lines.

Ramos PMM, Pezuk JA, Castro-Gamero AM, Oliveira HF, Scrideli CA, Umezawa K, Tone LG.

Anticancer Agents Med Chem. 2018;18(4):541-549. doi: 10.2174/1871520617666171113151335.

PMID:
29141555
9.

Microenvironmental stromal cells abrogate NF-κB inhibitor-induced apoptosis in chronic lymphocytic leukemia.

Simon-Gabriel CP, Foerster K, Saleem S, Bleckmann D, Benkisser-Petersen M, Thornton N, Umezawa K, Decker S, Burger M, Veelken H, Claus R, Dierks C, Duyster J, Zirlik K.

Haematologica. 2018 Jan;103(1):136-147. doi: 10.3324/haematol.2017.165381. Epub 2017 Nov 9.

10.

The unfolded protein response mediated by PERK is casually related to the pathogenesis of intervertebral disc degeneration.

Fujii T, Fujita N, Suzuki S, Tsuji T, Takaki T, Umezawa K, Watanabe K, Miyamoto T, Horiuchi K, Matsumoto M, Nakamura M.

J Orthop Res. 2018 May;36(5):1334-1345. doi: 10.1002/jor.23787. Epub 2017 Nov 28.

PMID:
29080374
11.

Novel p-terphenyl glycoside with a rare 2,6-dideoxyhexopyranose moiety from Actinomycete strain SF2911 that inhibits cancer cell migration.

Wang L, Li M, Tang J, Lin Y, Sidthipong K, Sumida N, Kushida N, Umezawa K.

J Antibiot (Tokyo). 2017 Oct;70(10):987-990. doi: 10.1038/ja.2017.83. Epub 2017 Jul 19.

PMID:
28951608
12.

A novel inhibitor of farnesyltransferase with a zinc site recognition moiety and a farnesyl group.

Tanaka A, Radwan MO, Hamasaki A, Ejima A, Obata E, Koga R, Tateishi H, Okamoto Y, Fujita M, Nakao M, Umezawa K, Tamanoi F, Otsuka M.

Bioorg Med Chem Lett. 2017 Aug 15;27(16):3862-3866. doi: 10.1016/j.bmcl.2017.06.047. Epub 2017 Jun 20.

PMID:
28666734
13.

Conophylline inhibits non-alcoholic steatohepatitis in mice.

Nakade Y, Sakamoto K, Yamauchi T, Inoue T, Kobayashi Y, Yamamoto T, Ishii N, Ohashi T, Sumida Y, Ito K, Nakao H, Fukuzawa Y, Umezawa K, Yoneda M.

PLoS One. 2017 Jun 8;12(6):e0178436. doi: 10.1371/journal.pone.0178436. eCollection 2017.

14.

Clinical Serum Therapy: Benefits, Cautions, and Potential Applications.

Hifumi T, Yamamoto A, Ato M, Sawabe K, Morokuma K, Morine N, Kondo Y, Noda E, Sakai A, Takahashi J, Umezawa K.

Keio J Med. 2017 Dec 25;66(4):57-64. doi: 10.2302/kjm.2016-0017-IR. Epub 2017 Apr 28. Review.

15.

External application of NF-κB inhibitor DHMEQ suppresses development of atopic dermatitis-like lesions induced with DNCB/OX in BALB/c mice.

Jiang X, Lan Y, Wei B, Dai C, Gu Y, Ma J, Liu X, Umezawa K, Zhang Y.

Immunopharmacol Immunotoxicol. 2017 Jun;39(3):157-164. doi: 10.1080/08923973.2017.1312436.

PMID:
28418286
16.

Simultaneous and multi-point measurement of ammonia emanating from human skin surface for the estimation of whole body dermal emission rate.

Furukawa S, Sekine Y, Kimura K, Umezawa K, Asai S, Miyachi H.

J Chromatogr B Analyt Technol Biomed Life Sci. 2017 May 15;1053:60-64. doi: 10.1016/j.jchromb.2017.03.034. Epub 2017 Apr 2.

PMID:
28411465
17.

Abnormal differentiation of stem cells into enteroendocrine cells in rats with DSS-induced colitis.

El-Salhy M, Umezawa K, Hatlebakk JG, Gilja OH.

Mol Med Rep. 2017 Apr;15(4):2106-2112. doi: 10.3892/mmr.2017.6266. Epub 2017 Mar 1.

18.

Inhibition of MMP-2-mediated cellular invasion by NF-κB inhibitor DHMEQ in 3D culture of breast carcinoma MDA-MB-231 cells: A model for early phase of metastasis.

Ukaji T, Lin Y, Okada S, Umezawa K.

Biochem Biophys Res Commun. 2017 Mar 25;485(1):76-81. doi: 10.1016/j.bbrc.2017.02.022. Epub 2017 Feb 8.

PMID:
28188787
19.

Inhibition of NF-kappaB with Dehydroxymethylepoxyquinomicin modifies the function of human peritoneal mesothelial cells.

Sosińska P, Baum E, Maćkowiak B, Staniszewski R, Jasinski T, Umezawa K, Bręborowicz A.

Am J Transl Res. 2016 Dec 15;8(12):5756-5765. eCollection 2016.

20.

Rational design, synthesis and in vitro evaluation of novel exo-methylene butyrolactone salicyloylamide as NF-κB inhibitor.

Sidthipong K, Ma J, Yu WL, Wang YF, Kobayashi S, Kishino S, Koide N, Yokochi T, Kato K, Okada S, Umezawa K.

Bioorg Med Chem Lett. 2017 Feb 1;27(3):562-566. doi: 10.1016/j.bmcl.2016.12.017. Epub 2016 Dec 8.

PMID:
28003138

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