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Items: 1 to 20 of 122

1.

Rif1 promotes association of G-quadruplex (G4) by its specific G4 binding and oligomerization activities.

Masai H, Fukatsu R, Kakusho N, Kanoh Y, Moriyama K, Ma Y, Iida K, Nagasawa K.

Sci Rep. 2019 Jun 13;9(1):8618. doi: 10.1038/s41598-019-44736-9.

2.

Impact of Small Molecules on Intermolecular G-Quadruplex Formation.

Gyawali P, Gc K, Ma Y, Abeysirigunawardena S, Nagasawa K, Balci H.

Molecules. 2019 Apr 20;24(8). pii: E1570. doi: 10.3390/molecules24081570.

3.

Stereoselective Synthesis of Four Calcitriol Lactone Diastereomers at C23 and C25.

Nagata A, Akagi Y, Masoud SS, Yamanaka M, Kittaka A, Uesugi M, Odagi M, Nagasawa K.

J Org Chem. 2019 Jun 21;84(12):7630-7641. doi: 10.1021/acs.joc.9b00403. Epub 2019 Apr 24.

PMID:
30985122
4.

Model studies for isolation of G-quadruplex-forming DNA sequences through a pull-down strategy with macrocyclic polyoxazole.

Iida K, Tsushima Y, Ma Y, Sedghi Masoud S, Sakuma M, Yokoyama T, Yoshida W, Ikebukuro K, Nagasawa K.

Bioorg Med Chem. 2019 Apr 15;27(8):1742-1746. doi: 10.1016/j.bmc.2019.02.056. Epub 2019 Mar 1.

PMID:
30842030
5.

Synthesis and Telomeric G-Quadruplex-Stabilizing Ability of Macrocyclic Hexaoxazoles Bearing Three Side Chains.

Ma Y, Iida K, Sasaki S, Hirokawa T, Heddi B, Phan AT, Nagasawa K.

Molecules. 2019 Jan 11;24(2). pii: E263. doi: 10.3390/molecules24020263.

6.

Synthesis of All Stereoisomers of RK460 and Evaluation of Their Activity and Selectivity as Abscisic Acid Receptor Antagonists.

Mikame Y, Yoshida K, Hashizume D, Hirai G, Nagasawa K, Osada H, Sodeoka M.

Chemistry. 2019 Mar 7;25(14):3496-3500. doi: 10.1002/chem.201806056. Epub 2019 Feb 12.

PMID:
30589135
7.

i-Motif-Binding Ligands and Their Effects on the Structure and Biological Functions of i-Motif.

Sedghi Masoud S, Nagasawa K.

Chem Pharm Bull (Tokyo). 2018;66(12):1091-1103. doi: 10.1248/cpb.c18-00720. Review.

8.

Random Formation of G-Quadruplexes in the Full-Length Human Telomere Overhangs Leads to a Kinetic Folding Pattern with Targetable Vacant G-Tracts.

Abraham Punnoose J, Ma Y, Hoque ME, Cui Y, Sasaki S, Guo AH, Nagasawa K, Mao H.

Biochemistry. 2018 Dec 26;57(51):6946-6955. doi: 10.1021/acs.biochem.8b00957. Epub 2018 Dec 11.

PMID:
30480434
9.

Binding of a Telomestatin Derivative Changes the Mechanical Anisotropy of a Human Telomeric G-Quadruplex.

Jonchhe S, Ghimire C, Cui Y, Sasaki S, McCool M, Park S, Iida K, Nagasawa K, Sugiyama H, Mao H.

Angew Chem Int Ed Engl. 2019 Jan 14;58(3):877-881. doi: 10.1002/anie.201811046. Epub 2018 Dec 12.

PMID:
30476359
10.

Molecular architecture of G-quadruplex structures generated on duplex Rif1-binding sequences.

Masai H, Kakusho N, Fukatsu R, Ma Y, Iida K, Kanoh Y, Nagasawa K.

J Biol Chem. 2018 Nov 2;293(44):17033-17049. doi: 10.1074/jbc.RA118.005240. Epub 2018 Sep 14.

PMID:
30217821
11.

A force sensor that converts fluorescence signal into force measurement utilizing short looped DNA.

Mustafa G, Chuang CY, Roy WA, Farhath MM, Pokhrel N, Ma Y, Nagasawa K, Antony E, Comstock MJ, Basu S, Balci H.

Biosens Bioelectron. 2018 Dec 15;121:34-40. doi: 10.1016/j.bios.2018.08.073. Epub 2018 Aug 31.

PMID:
30195120
12.

Development of G-quadruplex ligands for selective induction of a parallel-type topology.

Ma Y, Tsushima Y, Sakuma M, Sasaki S, Iida K, Okabe S, Seimiya H, Hirokawa T, Nagasawa K.

Org Biomol Chem. 2018 Oct 17;16(40):7375-7382. doi: 10.1039/c8ob01702f.

PMID:
30187070
13.

Analysis of Interactions between Telomeric i-Motif DNA and a Cyclic Tetraoxazole Compound.

Sedghi Masoud S, Yamaoki Y, Ma Y, Marchand A, Winnerdy FR, Gabelica V, Phan AT, Katahira M, Nagasawa K.

Chembiochem. 2018 Nov 2;19(21):2268-2272. doi: 10.1002/cbic.201800425. Epub 2018 Oct 12.

14.

Esterification of PQQ Enhances Blood-Brain Barrier Permeability and Inhibitory Activity against Amyloidogenic Protein Fibril Formation.

Tsukakoshi K, Yoshida W, Kobayashi M, Kobayashi N, Kim J, Kaku T, Iguchi T, Nagasawa K, Asano R, Ikebukuro K, Sode K.

ACS Chem Neurosci. 2018 Dec 19;9(12):2898-2903. doi: 10.1021/acschemneuro.8b00355. Epub 2018 Aug 8.

PMID:
30074759
15.

Asymmetric Epoxidation of 1,4-Naphthoquinones Catalyzed by Guanidine-Urea Bifunctional Organocatalyst.

Kawaguchi M, Nakano K, Hosoya K, Orihara T, Yamanaka M, Odagi M, Nagasawa K.

Org Lett. 2018 May 18;20(10):2811-2815. doi: 10.1021/acs.orglett.8b00641. Epub 2018 May 2.

PMID:
29717876
16.

Synthesis of 2,6,7-Trisubstituted Prenylated indole.

Shiozawa M, Iida K, Odagi M, Yamanaka M, Nagasawa K.

J Org Chem. 2018 Jul 6;83(13):7276-7280. doi: 10.1021/acs.joc.7b03273. Epub 2018 Mar 14.

PMID:
29516739
17.

Identification of G-quadruplex clusters by high-throughput sequencing of whole-genome amplified products with a G-quadruplex ligand.

Yoshida W, Saikyo H, Nakabayashi K, Yoshioka H, Bay DH, Iida K, Kawai T, Hata K, Ikebukuro K, Nagasawa K, Karube I.

Sci Rep. 2018 Feb 15;8(1):3116. doi: 10.1038/s41598-018-21514-7.

18.

Author Correction: FAN1 interaction with ubiquitylated PCNA alleviates replication stress and preserves genomic integrity independently of BRCA2.

Porro A, Berti M, Pizzolato J, Bologna S, Kaden S, Saxer A, Ma Y, Nagasawa K, Sartori AA, Jiricny J.

Nat Commun. 2017 Dec 21;8(1):2285. doi: 10.1038/s41467-017-02130-x.

19.

Targeting STUB1-tissue factor axis normalizes hyperthrombotic uremic phenotype without increasing bleeding risk.

Shashar M, Belghasem ME, Matsuura S, Walker J, Richards S, Alousi F, Rijal K, Kolachalama VB, Balcells M, Odagi M, Nagasawa K, Henderson JM, Gautam A, Rushmore R, Francis J, Kirchhofer D, Kolandaivelu K, Sherr DH, Edelman ER, Ravid K, Chitalia VC.

Sci Transl Med. 2017 Nov 22;9(417). pii: eaam8475. doi: 10.1126/scitranslmed.aam8475.

20.

FAN1 interaction with ubiquitylated PCNA alleviates replication stress and preserves genomic integrity independently of BRCA2.

Porro A, Berti M, Pizzolato J, Bologna S, Kaden S, Saxer A, Ma Y, Nagasawa K, Sartori AA, Jiricny J.

Nat Commun. 2017 Oct 20;8(1):1073. doi: 10.1038/s41467-017-01074-6. Erratum in: Nat Commun. 2017 Dec 21;8(1):2285.

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