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Health Benefits of Lactobacillus gasseri CP2305 Tablets in Young Adults Exposed to Chronic Stress: A Randomized, Double-Blind, Placebo-Controlled Study.

Nishida K, Sawada D, Kuwano Y, Tanaka H, Rokutan K.

Nutrients. 2019 Aug 10;11(8). pii: E1859. doi: 10.3390/nu11081859.


HnRNPA1 interacts with G-quadruplex in the TRA2B promoter and stimulates its transcription in human colon cancer cells.

Nishikawa T, Kuwano Y, Takahara Y, Nishida K, Rokutan K.

Sci Rep. 2019 Jul 16;9(1):10276. doi: 10.1038/s41598-019-46659-x.


A novel long non-coding RNA from the HOXA6-HOXA5 locus facilitates colon cancer cell growth.

Saijo S, Kuwano Y, Tange S, Rokutan K, Nishida K.

BMC Cancer. 2019 Jun 3;19(1):532. doi: 10.1186/s12885-019-5715-0.


ZNF350 promoter methylation accelerates colon cancer cell migration.

Tanaka H, Kuwano Y, Nishikawa T, Rokutan K, Nishida K.

Oncotarget. 2018 Dec 4;9(95):36750-36769. doi: 10.18632/oncotarget.26353. eCollection 2018 Dec 4.


Nucleolin facilitates nuclear retention of an ultraconserved region containing TRA2β4 and accelerates colon cancer cell growth.

Satake Y, Kuwano Y, Nishikawa T, Fujita K, Saijo S, Itai M, Tanaka H, Nishida K, Rokutan K.

Oncotarget. 2018 Jun 1;9(42):26817-26833. doi: 10.18632/oncotarget.25510. eCollection 2018 Jun 1.


Role of geranylgeranylacetone as non-toxic HSP70 inducer in liver surgery: clinical application.

Tashiro S, Miyake H, Rokutan K.

J Hepatobiliary Pancreat Sci. 2018 May;25(5):269-274. doi: 10.1002/jhbp.549. Epub 2018 Apr 15. Review.


Geranylgeranylacetone prevents stress-induced decline of leptin secretion in mice.

Itai M, Kuwano Y, Nishikawa T, Rokutan K, Kensei N.

J Med Invest. 2018;65(1.2):103-109. doi: 10.2152/jmi.65.103.


RNA Binding Proteins and Genome Integrity.

Nishida K, Kuwano Y, Nishikawa T, Masuda K, Rokutan K.

Int J Mol Sci. 2017 Jun 23;18(7). pii: E1341. doi: 10.3390/ijms18071341. Review.


Effects of milk product intake on thigh muscle strength and NFKB gene methylation during home-based interval walking training in older women: A randomized, controlled pilot study.

Masuki S, Nishida K, Hashimoto S, Morikawa M, Takasugi S, Nagata M, Taniguchi S, Rokutan K, Nose H.

PLoS One. 2017 May 17;12(5):e0176757. doi: 10.1371/journal.pone.0176757. eCollection 2017.


Response Predictors of S-1, Cisplatin, and Docetaxel Combination Chemotherapy for Metastatic Gastric Cancer: Microarray Analysis of Whole Human Genes.

Kitamura S, Tanahashi T, Aoyagi E, Nakagawa T, Okamoto K, Kimura T, Miyamoto H, Mitsui Y, Rokutan K, Muguruma N, Takayama T.

Oncology. 2017;93(2):127-135. doi: 10.1159/000464329. Epub 2017 May 17.


Adverse parenting is associated with blunted salivary cortisol awakening response and altered expression of glucocorticoid receptor β and β2-adrenergic receptor mRNAs in leukocytes in Japanese medical students.

Kawai T, Kuwano Y, Masuda K, Fujita K, Tanaka H, Nishikawa T, Rokutan K, Nishida K.

Stress. 2017 Mar;20(2):159-166. doi: 10.1080/10253890.2017.1297415. Epub 2017 Mar 12.


Downregulation of microRNA-100/microRNA-125b is associated with lymph node metastasis in early colorectal cancer with submucosal invasion.

Fujino Y, Takeishi S, Nishida K, Okamoto K, Muguruma N, Kimura T, Kitamura S, Miyamoto H, Fujimoto A, Higashijima J, Shimada M, Rokutan K, Takayama T.

Cancer Sci. 2017 Mar;108(3):390-397. doi: 10.1111/cas.13152.


Homeodomain-Interacting Protein Kinase-2: A Critical Regulator of the DNA Damage Response and the Epigenome.

Kuwano Y, Nishida K, Akaike Y, Kurokawa K, Nishikawa T, Masuda K, Rokutan K.

Int J Mol Sci. 2016 Sep 27;17(10). pii: E1638. Review.


Serine/arginine-rich splicing factor 7 regulates p21-dependent growth arrest in colon cancer cells.

Saijo S, Kuwano Y, Masuda K, Nishikawa T, Rokutan K, Nishida K.

J Med Invest. 2016;63(3-4):219-26. doi: 10.2152/jmi.63.219.


Morphological Characteristics and Location of Missed, Advanced Colorectal Neoplasms after Colonoscopy.

Kawamura T, Uno K, Tanaka K, Ueda Y, Sakiyama N, Nishida K, Rokutan K, Yasuda K.

J Med Invest. 2016;63(3-4):163-70. doi: 10.2152/jmi.63.163.


Fermented Milk Containing Lactobacillus casei Strain Shirota Preserves the Diversity of the Gut Microbiota and Relieves Abdominal Dysfunction in Healthy Medical Students Exposed to Academic Stress.

Kato-Kataoka A, Nishida K, Takada M, Kawai M, Kikuchi-Hayakawa H, Suda K, Ishikawa H, Gondo Y, Shimizu K, Matsuki T, Kushiro A, Hoshi R, Watanabe O, Igarashi T, Miyazaki K, Kuwano Y, Rokutan K.

Appl Environ Microbiol. 2016 May 31;82(12):3649-58. doi: 10.1128/AEM.04134-15. Print 2016 Jun 15.


HuR regulates alternative splicing of the TRA2β gene in human colon cancer cells under oxidative stress.

Akaike Y, Masuda K, Kuwano Y, Nishida K, Kajita K, Kurokawa K, Satake Y, Shoda K, Imoto I, Rokutan K.

Mol Cell Biol. 2014 Aug;34(15):2857-73. doi: 10.1128/MCB.00333-14. Epub 2014 May 27.


Oxidative stress-inducible truncated serine/arginine-rich splicing factor 3 regulates interleukin-8 production in human colon cancer cells.

Kano S, Nishida K, Kurebe H, Nishiyama C, Kita K, Akaike Y, Kajita K, Kurokawa K, Masuda K, Kuwano Y, Tanahashi T, Rokutan K.

Am J Physiol Cell Physiol. 2014 Feb 1;306(3):C250-62. doi: 10.1152/ajpcell.00091.2013. Epub 2013 Nov 27.


Truncated serine/arginine-rich splicing factor 3 accelerates cell growth through up-regulating c-Jun expression.

Kano S, Nishida K, Nishiyama C, Akaike Y, Kajita K, Kurokawa K, Masuda K, Kuwano Y, Tanahashi T, Rokutan K.

J Med Invest. 2013;60(3-4):228-35.


Chronic academic stress increases a group of microRNAs in peripheral blood.

Honda M, Kuwano Y, Katsuura-Kamano S, Kamezaki Y, Fujita K, Akaike Y, Kano S, Nishida K, Masuda K, Rokutan K.

PLoS One. 2013 Oct 9;8(10):e75960. doi: 10.1371/journal.pone.0075960. eCollection 2013.

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